htmx gives you access to AJAX, CSS Transitions, WebSockets and Server Sent Events directly in HTML, using attributes, so you can build modern user interfaces with the simplicity and power of hypertexthtmx is small (~14k min.gz’d), dependency-free, extendable, IE11 compatible

Hyperscript is a scripting language for doing front end web development. It is designed to make it very easy to respond to events and do simple DOM manipulation in code that is directly embedded on elements on a web page.

Biff is a batteries-included web framework for Clojure. Launch new projects quickly without getting bogged down in complexity later.