Episode list

After a cargo ship docks in the harbor,a diamond smuggling crewman's body is found and it's loaded with Cholera. Locke and the police force must race against time to locate and quarantine all his shipmates, including his killer, lest they spread an epidemic through the city.

A lunatic is calling in false medical emergencies and killing the paramedics that respond. After losing his last partner, Dr. Locke is assigned Andrea, a colleague he formerly dated. Simon becomes overprotective but she insists she can do the job. The killer shows no partiality.

Dr. Simon Locke treats an extortionist Paul Shaver after he is shot. When he once again evades conviction, Simon works to have him brought to justice. Shaver's girlfriend Arline may provide the crucial information.

A politician witnesses a mob murder but lets his mistress Nora tell the police she saw it. Dr. Locke becomes involved after he says she has a medical condition to make that impossible but a hitman still goes after her.

Bill Grady is a exceptional hockey player but drugs and a gambling syndicate have their hold on him. Dr. Locke discovers his hidden addiction and after convincing a protective brother Ed of the situation, they take drastic action.

Dr. Simon Locke is called to treat a severely beaten woman. Persistent questioning by the physician reveals that Phyllis and Delbert are siblings who run a badger scheme. Their current target is a local politician who doesn't take kindly to being blackmailed.

Insurance agent Ben Grover stumbles onto a lucrative scam his bosses are using to steal from the company. Before he acts on it, an assassin is used to take him out, but they manage to only kill his wife instead. Grover then turns the tables seeking a deadly revenge.

Crime figure Tabor is in custody so his henchman kidnap prosecutor Paul Madden in front of his wife. Exton contacts Lt. Gordon and Locke to exchange the two but they decline. A wounded Madden needs rescuing before he dies.

Frank is a veteran beat cop who Dr. Locke discovers is slowly being poisoned after he collapses. The two team up to discover who is behind the attempt and why. The return of a drug kingpin may provide the answer.

Several nurses are killed and one disappears leading Dr. Locke to zero in on a charismatic young doctor. The hospital administrator John Warren defends him, eventually drawing attention to himself. Simon must evaluate the evidence to save a young woman's life.

Detective Richard Gar is accused of being a dirty cop in a mobster's memoir. He declares his innocence to Dr. Locke who believes him. But his actions to clear his name go too far.

A second rate, hot-headed lounge singer is injured when his girlfriend is abducted, but nobody believes it all isn't part of a cheap publicity stunt. Desperate, he begs his wealthy, but very much estranged father for the ransom money but gets turned down.

A mental block afflicts a museum guard who was the sole witness to a murder.

When innocent bystanders are wounded when a mob boss is gun down the overeaction of Lt. Gordon causes concern. Dr. Locke questions his boss but missing medication leads to the answer of Gordon's strange behavior.

Driving along, a girl is hijacked at gunpoint by a deranged woman escapee obsessed with her face, scarred from a childhood accident. She forces the girl up to the crumbling balcony of a condemned old building, threatening a murder suicide if anyone gets near, yet Locke must try to talk her down.

After a bulldozer errantly knocks down a wall at a demo project, the father of the demolition team is rushed to the hospital while his son, Niko (Chakiris), finds $200,000 in the debris. After some debate, Niko agrees to turn the money over to police. The only trouble is the money is from a nearby robbery, in which $300,000 was stolen. The culprits want the missing loot.

Careening off the road because of sabotaged brakes, a car crashes in a chemical warehouse. Locke and special fire rescue units try to extract a woman pinned in the wreck before explosive gases ignite, as her wheelchair-bound husband insists his business partner had to be responsible.

Gans is released from prison for securities theft and immediately collapses, drawing Dr. Locke to the scene. Kramer, an insurance investigator, is keeping close watch on Gans as the securities were never recovered. In addition Kramer used to date Jill Gans, his daughter.

An old black man and a white boy living on the fringe scrounge an auto wreck yard for things to paint,yet he becomes the target of an assassin.The boy is encouraged to keep silent, and it's revealed the old man has a huge amount of possible counterfeit cash.

Andy Carrigan, a student from Ireland, is warned to stop looking for his father who disappeared ten years earlier. Dr. Locke becoming involved after treating Andy's injured hand. John Carrigan makes contact with his son but needs to keep his distance because he is involved in human trafficking.

Dr. Simon Locke is called to a prominent citizen's house after a dead man is discovered. Police determine the man recently escaped from prison and his accomplice Frey is likely nearby and a murderer. Simon is instrumental in solving the case.

After a party, a millionaire's mansion is invaded and his prize painting is stolen, and a guard is wounded. His neglected wife turns out to have organized it as a prank, but it has spiraled out of control when the thief is determined to collect ransom.

Ed Morgan runs a construction business and has several near fatal "accidents". Dr. Locke patches him up but is determined to get to the source of the problem. Ed wants out of a syndicate smuggling opration but they consider him essential.

Charley is part of a loan shark operation but hasn't been turning in his client's payments. When several of them are severely beaten Dr. Locke is called in and he starts to add things up. Charley's daughter Ruth and her expensive tastes may be the problem.

No-account son-in-law of a wealthy drug dealer steals a car one day with a valuable shipment and his naive wife. They crash, and he must escape the hospital with the shipment in a suitcase, his father-in-law and the mob's wrath, as Dr. Locke tries to intervene.