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Johnny Galecki, Simon Helberg, Jim Parsons, and Kunal Nayyar in The Big Bang Theory (2007)

Goofs

The Focus Attenuation

The Big Bang Theory

Edit

Factual errors

Sheldon erroneously defines Negative Reinforcement as "withdrawal of a positive stimulus". In fact, this is Negative Punishment, e.g. denying a child his dessert because of a misbehaviour earlier in the day. Negative Reinforcement is the withdrawal of a NEGATIVE stimulus. For example, safe driving is "reinforced" by motorists' desire to avoid a traffic ticket .
Sheldon says that the geosynchronous satellite was inspired by science fiction. While the idea did come from the SF writer Arthur C. Clarke, it wasn't from a story but from an article in a technical magazine, Wireless World, in 1945.

Incorrectly regarded as goofs

Amy was placed on the no fly list for hitting a TSA agent, when the girls had a Vegas trip planned before, on the The Love Spell Potential (2013).

But since then, she could have been taken off the "no fly" list.

Revealing mistakes

Leonard claims that all the ideas the group thought of are written in a notebook and proceeds to read some of them out. However, as he flips over the pages, it is clear that they are all blank,

Miscellaneous

Sheldon Cooper states the term "Negative Reinforcement" is used incorrectly, however previously in The Gothowitz Deviation (2009), he uses the term "Negative Reinforcement" incorrectly too.
When Amy takes off with Penny's laptop through the door, Penny says that she (Amy) went into the walk in closet. However, when Amy opens the door, it's clearly not a closet. You can see a wall with a picture and light fixture hanging on it and Amy runs to the right of what appears to be a hallway.

Plot holes

A few seasons back, the guys did invent an algorithm app.

Character error

The guys devise verb tenses that the guys devise to describe events a t various points in a time-travelling timeline. However, even given that these are for comic effect, the word combinations that the use make no sense.
Leonard says "We sent the girls away so we could focus." They didn't send them. When they found out that the guys would be occupied, they themselves decided to go.

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