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Immunology news
Oncology & Cancer
Cancer-fighting bacterial product 'cocktails' may offer personalized treatment
Bacteria may be the next frontier in cancer treatment, according to a team led by researchers at Penn State that devised a new approach of creating bacteria-derived mixtures—or cocktails—to help fight bladder cancer. ...
17 hours ago
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Oncology & Cancer
Blocking Claudin-4 protein may help immune system fight aggressive ovarian cancer
Scientists at The University of Texas at El Paso have found a promising new target in the fight against high-grade serous carcinoma, an aggressive form of ovarian cancer. Less than 50% of women survive five years after diagnosis, ...
17 hours ago
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Study compares immune responses from three major COVID-19 vaccine types
A recent study has provided the first side-by-side comparison of how three major COVID-19 vaccine types differ in triggering immune responses and sustaining protection, according to an analysis published in JCI Insight.
15 hours ago
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Why some people with HIV achieve remission after antibody treatment
Researchers led by a team from Mass General Brigham and the Ragon Institute have discovered why some people living with HIV who are given a treatment called broadly neutralizing anti-HIV antibodies (bNAbs) can safely stop ...
Dec 1, 2025
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Long-term HIV control: Combination therapy points way to a possible cure
A new study from UC San Francisco shows it may be possible to control HIV without long-term antiviral treatment—an advance that points the way toward a possible cure for a disease that affects 40 million people around the ...
Dec 1, 2025
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Unexpected pathway for IgA antibody production may help improve vaccines
Scientists led by Stephanie Eisenbarth, MD, Ph.D., the Roy and Elaine Patterson Professor of Medicine and director of the Center for Human Immunobiology, have discovered how critical IgA antibodies are produced through unexpected ...
Dec 1, 2025
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Inflammation and metabolic stress combine to drive a new cell death pathway—mitoxyperilysis
In several disease conditions, including infections and cancers, innate immune activation and nutrient scarcity occur together. A study from St. Jude Children's Research Hospital, published in Cell, found that this combination ...
Dec 1, 2025
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Study investigates treatment safety in cases of late HIV diagnosis
About 40 million people worldwide are living with HIV infection. In the United Kingdom, there are approximately 100,000 people affected. If the infection is not treated, the body will eventually be unable to defend itself ...
Dec 1, 2025
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A molecule opens a breach in HIV, providing access to its reservoirs
An international team led by two Université de Montréal researchers has unveiled how a molecule capable of opening the "shell" of HIV improves the elimination of infected cells.
Dec 1, 2025
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Lack of dietary iron may impair immune cells' ability to fight influenza
New research published in The Journal of Immunology suggests that a lack of dietary iron can negatively affect the ability of immune cells to respond to viral infection in the lungs. In mice with dietary iron deficiency and ...
Dec 1, 2025
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How to stay healthy on HIV treatment, and what side effects to look out for
HIV treatment has delivered life-altering advantages. Antiretroviral therapy has led to a reduced mortality and improved life expectancy for people living with HIV. Nearly 41 million people were living with HIV in 2024. Eastern ...
Dec 1, 2025
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Predicting a rare but life-altering complication of common cancer treatment
A new study published in the Journal of Clinical Investigation has identified biomarkers that predict the likelihood of a patient developing checkpoint inhibitor-associated autoimmune diabetes before they are treated with ...
Nov 29, 2025
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RSV vaccines could offer protection against asthma
Belgian scientists from VIB and Ghent University (UGent), together with Danish collaborators, have uncovered compelling evidence that early-infancy infection with respiratory syncytial virus (RSV) significantly increases ...
Nov 28, 2025
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Healing the gut after cancer therapy: Immune cells turn damage into repair
Regulatory T cells (Treg cells), a specialized type of immune cell, are usually seen as "peacekeepers" that prevent excessive immune attacks. Surprisingly, a new study published in Signal Transduction and Targeted Therapy ...
Nov 28, 2025
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New protocol for Treg expansion uses targeted immunotherapy to reduce transplant complications
In preclinical studies, researchers found that priming the immune system with a Treg-expanding therapy before stem cell transplant boosted survival, protected vital organs, and promoted a balanced gut microbiome—offering ...
Nov 27, 2025
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Why certain arthritis drugs don't work in rheumatoid arthritis
Cedars-Sinai investigators may have figured out why certain immunosuppressive treatments don't work well in rheumatoid arthritis. In a study published in Science Immunology, scientists trace the problem to specific changes ...
Nov 26, 2025
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How a mitochondrial mutation rewires immune function
Scientists have discovered how a mitochondrial mutation rewires immune function in a model of inherited primary mitochondrial disorders, which often lead to severe disability and death. They have discovered that this single ...
Nov 26, 2025
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Fighting two infections at once: Hepatitis C cure may relieve immune strain in HIV patients
The hepatitis C virus—HCV—can persist in the livers of those infected and even lead to liver disease or failure in extreme cases. It affects tens of millions of people worldwide and there is no vaccine to prevent infection, ...
Nov 26, 2025
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How antibody therapy clears Alzheimer's plaques: Key immune mechanism identified
Lecanemab, sold under the name Leqembi, is a monoclonal antibody therapy for Alzheimer's disease that clears toxic amyloid plaques and delays cognitive decline. Researchers from VIB and KU Leuven have now demonstrated the ...
Nov 25, 2025
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Scientists develop one-product-fits-all immunotherapy for pancreatic cancer
Pancreatic cancer is among the deadliest forms of cancer, with most patients diagnosed after the disease has already spread throughout the body. The five-year survival rate for metastatic cases hovers around 2–3%, and median ...
Nov 25, 2025
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Why the 'gut brain' plays a central role for allergies
An international research team led by scientists from Bern and Charité—Universitätsmedizin Berlin has identified a previously unknown function of the intestinal nervous system.
Nov 25, 2025
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Newly identified immune cell type could hold key to preventing scar tissue buildup in wounds
Researchers at the University of Arizona have uncovered a previously unknown population of circulating immune cells that play a critical role in fibrosis, the buildup of scar tissue that can lead to organ failure and disfigurement. ...
Nov 25, 2025
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Myeloid mimicry enables kidney tumors to resist immunotherapy and worsen rapidly, study finds
Researchers at The University of Texas MD Anderson Cancer Center have found that renal medullary carcinoma (RMC) cells use an adaptive mechanism called "myeloid mimicry" to hide from the immune system and promote disease ...
Nov 25, 2025
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Too sick to socialize: How the brain and immune system promote staying in bed
"I just can't make it tonight. You have fun without me." Across much of the animal kingdom, when infection strikes, social contact shuts down. A new study details how the immune and central nervous systems implement this ...
Nov 25, 2025
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Research challenges idea that gene PTPN22 boosts production of interferons
A new paper from the University of Kansas overturns the idea that a "risk gene" carried by millions of people worldwide influences production of type 1 interferon, a workhorse of the immune system. The work is published in ...
Nov 25, 2025
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