WO2002000001A3 - HUMAN G PROTEIN-COUPLED RECEPTOR IGPcR20, AND USES THEREOF - Google Patents

HUMAN G PROTEIN-COUPLED RECEPTOR IGPcR20, AND USES THEREOF Download PDF

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Publication number
WO2002000001A3
WO2002000001A3 PCT/EP2001/007533 EP0107533W WO0200001A3 WO 2002000001 A3 WO2002000001 A3 WO 2002000001A3 EP 0107533 W EP0107533 W EP 0107533W WO 0200001 A3 WO0200001 A3 WO 0200001A3
Authority
WO
WIPO (PCT)
Prior art keywords
igpcr20
protein
receptor
coupled receptor
express
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2001/007533
Other languages
French (fr)
Other versions
WO2002000001A2 (en
Inventor
Frank Wattler
Sigrid Wattler
Paul Trommler
Michael C Nehls
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ingenium Pharmaceuticals GmbH
Original Assignee
Ingenium Pharmaceuticals GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ingenium Pharmaceuticals GmbH filed Critical Ingenium Pharmaceuticals GmbH
Priority to AU2001287574A priority Critical patent/AU2001287574A1/en
Publication of WO2002000001A2 publication Critical patent/WO2002000001A2/en
Publication of WO2002000001A3 publication Critical patent/WO2002000001A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Reproductive Health (AREA)
  • Zoology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Cell Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

A novel human G protein-coupled receptor (GPcR) protein, IGPcR20, is identified and characterized. IGPcR20-encoding nucleotides, IGPcR20 proteins and fusion proteins, antibodies to the receptor, host cell expression systems, animal models in which the IGPcR20 gene is mutated, recombinant knock-out animals that do not express IGPcR20 and transgenic animals that express an IGPcR20 transgene are encompasssed by the invention, as are compounds that modulate gene expression or receptor activity of IGPcR20 and their use for drug screening, and diagnosis or treatment of diseases and disorders, particularly cancer, reproductive disorders and infertility related to epididymal dysfunction.
PCT/EP2001/007533 2000-06-30 2001-07-02 HUMAN G PROTEIN-COUPLED RECEPTOR IGPcR20, AND USES THEREOF Ceased WO2002000001A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001287574A AU2001287574A1 (en) 2000-06-30 2001-07-02 Human g protein-coupled receptor igpcr20, and uses thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21577700P 2000-06-30 2000-06-30
US60/215,777 2000-06-30

Publications (2)

Publication Number Publication Date
WO2002000001A2 WO2002000001A2 (en) 2002-01-03
WO2002000001A3 true WO2002000001A3 (en) 2002-08-22

Family

ID=22804341

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/007533 Ceased WO2002000001A2 (en) 2000-06-30 2001-07-02 HUMAN G PROTEIN-COUPLED RECEPTOR IGPcR20, AND USES THEREOF

Country Status (2)

Country Link
AU (1) AU2001287574A1 (en)
WO (1) WO2002000001A2 (en)

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DE202016006615U1 (en) 2016-10-26 2018-01-30 WIK - ELEKTROGERÄTE Entwicklungs- und Service-GmbH & Co. KG Hair styling device for applying a care substance by means of compressed air
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11690853B2 (en) 2015-06-29 2023-07-04 Reveragen Biopharma, Inc. Non-hormonal steroid modulators of NF-κβ for treatment of disease

Also Published As

Publication number Publication date
WO2002000001A2 (en) 2002-01-03
AU2001287574A1 (en) 2002-01-08

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