Pavlo Hrab

Computational biologist, PhD | Pipelines and tools for microbial genomics

Computational biologist (PhD) working across microbiology and bioinformatics. I build reproducible pipelines and tools in R, Python, and Nextflow to make sense of large, messy biological datasets. My work covers metagenomics, transcriptomics, phylogenetics, functional annotation, and machine learning. I also work at the bench, culturing slow-growing bacteria, so I understand the data from both sides.

Pavlo Hrab

What I do

Pipelines & data engineering

Reproducible Nextflow workflows for working with metagenomics data

Genome mining

Biosynthetic gene clusters mining at scale with antiSMASH, and BiG-SCAPE, including lineages nobody has mined before

Multi-omics & ML

Metagenomics, metatranscriptomics and phylogenomics. Applying statistics and machine learning to draw a conclusion from them

Wet lab

Cultivation of slow-growing bacteria, PCR and sequencing - I generate data as well as analyse it

Featured Projects

Current research projects and ongoing work

Recent Publications

Selected recent research papers and conference proceedings.

New insights into the microbiome of the deep-sea sponge Inflatella pellicula and the secondary metabolic potential of metagenome-assembled genomes and the wider microbiome

Jackson, S. A., Hrab, P., Zdouc, M. M., Clarke, D. J., & Dobson, A. D. W.

Microbial Genomics, 12(1), 001602, 2026

MIBiG 4.0: advancing biosynthetic gene cluster curation through global collaboration

Mitja M Zdouc, Kai Blin, .... Pavlo Hrab,... Tilmann Weber, Marnix H Medema

Nucleic Acids Research 53(D1):D678–D690, 2025

Complete genome sequence of Streptomyces cyanogenus S136, producer of anticancer angucycline landomycin A.

Hrab, P., Rückert, C., Busche, T., Ostash, I., Kalinowski, J., Fedorenko, V., Yushchuk, O., & Ostash, B.

3 Biotech, 11(6), 282, 2021

Latest News

Recent updates, talks, and academic activities.