Profile

Computational biologist with a PhD in bioinformatics and microbiology. I build pipelines and open-source tools in Nextflow, Python and R, and use them on large sequencing datasets.

My work covers metagenomics, transcriptomics, phylogenomics, functional annotation and machine learning. During my PhD I cleaned and analysed 19,720 metagenome-assembled genomes with a pipeline I wrote and released, and ran a year-long cultivation study to isolate the bacteria behind them.

Available from 1 October 2026.

Work Experience

Postdoctoral researcher

Medema group, Bioinformatics group, Wageningen University & Research

Research Consortium: COMBO
  • Mined marine sponge metagenomes for biosynthetic gene clusters, and selected candidates for downstream heterologous expression

PhD Candidate

Medema group & Detmer Sipkema lab, Bioinformatics group & Molecular Ecology group, Wageningen University & Research

Research Consortium: MARBLES

Project: Treasures of the deep — biosynthetic profiling and cultivation of marine host-associated Acidobacteriota

  • Planned and led a year-long, uninterrupted isolation study of sponge-associated bacteria under unconventional cultivation conditions, uncovering new physiological properties in the isolates
  • Built a Nextflow pipeline that takes raw MAGs through quality filtering, chimerism removal, dereplication and taxonomic classification — used it to reduce 19,720 public Acidobacteriota genomes to a clean, species-level set.
  • Mined biosynthetic gene clusters across that set with antiSMASH and BiG-SCAPE, and wrote the tooling to explore the results (an iTOL annotation generator and a BiG-SCAPE domain-co-occurrence app)
  • Analysed 488 marine genomes across 16 families to separate host adaptation from shared ancestry, combining phylogenomics, Pfam-based feature matrices and random forest models
  • Used functional predictions from the metagenomes to design the isolation media, closing the loop between the computational and the wet-lab work
  • Supervised 2 MSc and 1 BSc student across both computational and molecular work
  • Presented at 11 multidisciplinary conferences across microbiology, bioinformatics and natural products

Related Global biosynthetic potential of Acidobacteriota · Host adaptations of marine Acidobacteriota · Targeted bacteria isolation from the deep-sea sponge Geodia barretti

Technical Support Specialist

Information System Development

  • Reproduced and diagnosed reported bugs against testing servers in a regulated, HIPAA-compliant environment

Laboratory Technician

Ivan Franko National University of Lviv

  • Sequenced, assembled and annotated the complete genome of Streptomyces cyanogenus S136, producer of the anticancer angucycline landomycin A (published in 3 Biotech)
  • Wrote two open-source tools during this period — rRNADif and BGCViz — and carried out the phylogenetics and BGC mining behind them

Related rRNADif · BGCViz

Selected Software

Open source, documented, and on GitHub. Full list on the Tools page.

ashelper

Turns antiSMASH and BiG-SCAPE output into iTOL annotation files.

Python · antiSMASH · BiG-SCAPE · iTOL tests · packaged · released

MAG Cleaning Pipeline

Nextflow pipeline that takes a directory of metagenome-assembled genomes and returns a dereplicated, quality-filtered, taxonomically classified set

Nextflow · CheckM2 · GUNC · dRep

BGCViz

Six BGC prediction tools disagree about where the clusters are. BGCViz shows you the overlap on a circular genome plot, so you can see what everything agrees on and what only one tool found.

R · Shiny · BioCircos · antiSMASH tests · packaged · docs · released · live demo

pfam_tools

Scans proteomes against Pfam-A, builds a QC-filtered presence/absence matrix, and annotates it with GO terms

Python · pyhmmer · Pfam-A · GO / GO-Slim

Contributions to other projects

metaWRAP — A widely used metagenome binning and analysis pipeline. I contributed a processing of nanopore reads RepositoryMy commits

Arrower — Draws gene cluster arrow diagrams from a GenBank file as SVG. I revived an abandoned Python 2 script: ported it to Python 3, gave it a real CLI, and added category-based arrow colouring with a legend. GitHubMy commits

Technical Skills

Languages

Python, R, Bash, SQL

Workflows & reproducibility

Nextflow, Conda, Git, working on remote Linux servers, R packaging, Shiny

Bioinformatics

Large-scale metagenomics and metatranscriptomics, BGC mining (antiSMASH, BiG-SCAPE, MIBiG), phylogenomics, functional annotation (Pfam, GO, HMMER/pyhmmer)

Statistics & ML

Statistical analysis in R and Python, random forests, clustering, enrichment testing, data cleaning and exploration

Laboratory

Cultivation of slow-growing and marine bacteria, E. coli and Streptomyces work, heterologous expression, (q)PCR

Education

M.Sc. in Genetics and Biotechnology

Ivan Franko National University of Lviv

Diploma cum laude. Thesis: Genome of S.cyanogenus S136: secondary metabolism potential

  • Performed biosynthetic gene cluster mining in S.cyanogenus S136 genome
  • Developed software to support the analysis

B.Sc. in Biology

Ivan Franko National University of Lviv

Thesis: Genetical control of morphogenesis in S.cyanogenus S136

  • Performed heterologous expression of selected gene clusters
  • Analysed phylogeny of rodlins and chaplins in Streptomycetaceae

Teaching Experience

Practical Computing for Biologists - Teaching Assistant

Wageningen University & Research

  • Assisted with providing practical advice for students during the assignments

Research methods in microbiology - Teaching Assistant

Wageningen University & Research

  • Developed course materials for computational part of the course
  • Assisted with teaching and practicals for the part of the course
  • Graded assignments and provided detailed feedback

Practical Computing for Biologists - Teaching Assistant

Wageningen University & Research

  • Assisted with providing practical advice for students during the assignments

Awards & Honors

Invited speaker

Summer School for Natural Products research 2025

Grant

19th European Conference on Computational Biology participation grant, Barcelona, Spain

Top 3 projects

Data Engineering and Security winter school (DES 2020), Lviv, Ukraine

1st place

4th Advanced in silico Drug design workshop/hackaton 2019, Olomouc, Czech Republic

Languages

English

Advanced (C1)

Ukrainian

Native

Dutch

Beginner (A1)