The African continent is regarded as the cradle of modern humans and African genomes
contain more genetic variation than those from any other continent, yet only a fraction of the …

Protein docking algorithms aim to calculate the three‐dimensional (3D) structure of a protein
complex starting from its unbound components. Although ab initio docking algorithms are …

Motivation: Aligning and comparing protein structures is important for understanding their
evolutionary and functional relationships. With the rapid growth of protein structure databases …

Motivation: In recent years, much structural information on protein domains and their pair-wise
interactions has been made available in public databases. However, it is not yet clear how …

Comparing, classifying and modelling protein structural interactions can enrich our
understanding of many biomolecular processes. This contribution describes Kbdock ( http://kbdock.…

… Fakim & Anisah W. … Anisah W. Ghoorah …

As the genomic profile across cancers varies from person to person, patient prognosis and
treatment may differ based on the mutational signature of each tumour. Thus, it is critical to …

Comparing and classifying protein domain interactions according to their three-dimensional
(3D) structures can help to understand protein structure-function and evolutionary …

The question of how best to compare and classify the (three‐dimensional) structures of proteins
is one of the most important unsolved problems in computational biology. To help tackle …

While the number of solved 3D protein structures continues to grow rapidly, the structural
rules that distinguish protein-protein interactions between different structural families are still …