Streptokinaza (SK ) je protein koji izlučuje nekoliko vrsta streptokoka. On se vezuje za i aktivira ljudski plazmin . SK se koristi kao efektivan i jeftin trombolitički lek u pojedinim slučajevima srčanog udara [ 2] i plućne embolije .[ 3] Streptokinaza pripada grupi lekova poznatih kao fibrinolitici .[ 4] [ 5]
↑ Rabijns A, De Bondt HL, De Ranter C (May 1997). „Three-dimensional structure of staphylokinase, a plasminogen activator with therapeutic potential”. Nat. Struct. Biol. 4 (5): 357–60. DOI :10.1038/nsb0597-357 . PMID 9145104 .
↑ Sikri N, Bardia A (2007). „A history of streptokinase use in acute myocardial infarction” . Tex Heart Inst J 34 (3): 318–27. PMC 1995058 . PMID 17948083 .
↑ Meneveau N, Schiele F, Vuillemenot A, et al. (July 1997). „Streptokinase vs alteplase in massive pulmonary embolism. A randomized trial assessing right heart haemodynamics and pulmonary vascular obstruction” . Eur. Heart J. 18 (7): 1141–8. PMID 9243149 .
↑ Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). „DrugBank 3.0: a comprehensive resource for omics research on drugs” . Nucleic Acids Res. 39 (Database issue): D1035-41. DOI :10.1093/nar/gkq1126 . PMC 3013709 . PMID 21059682 . edit
↑ David S. Wishart, Craig Knox, An Chi Guo, Dean Cheng, Savita Shrivastava, Dan Tzur, Bijaya Gautam, and Murtaza Hassanali (2008). „DrugBank: a knowledgebase for drugs, drug actions and drug targets” . Nucleic Acids Res 36 (Database issue): D901-6. DOI :10.1093/nar/gkm958 . PMC 2238889 . PMID 18048412 . edit