Klinefelter syndrome
Klinefelter syndrome, 47, XXY, or XXY syndrome is a genetic disorder where people have an extra number of X chromosomes.[1] People who have Klinefelter's Syndrome are often called "XXY Males", or "47, XXY Males".[2]
Effects
[change | change source]Males who have this condition are almost always infertile. This means that they cannot father babies.[3]
In other organisms
[change | change source]Any male mammal can have Klinefelter's Syndrome. The mouse is one example.[4] Tortoiseshell or calico markings on male cats are an indicator of Klinefelter's syndrome. These cats are considered to be the model organism for Klinefelter syndrome, because the gene for a cat's orange/black coat markings is found on the X chromosome. [5]
References
[change | change source]- ↑ Kumar, Vinay; Abbas, Abul K.; Fausto, Nelson (2005). Robbins and Cotran pathologic basis of disease (7th ed.). Philadelphia: Elsevier/Saunders. ISBN 978-0-7216-0187-8.
- ↑ Bock, Robert (1993). "Understanding Klinefelter Syndrome: A Guide for XXY Males and their Families" (HTML). NIH Pub. No. 93-3202. Office of Research Reporting, NICHD. Retrieved 2007-04-07.
- ↑ Denschlag, Dominik, MD; Clemens, Tempfer, MD; Kunze, Myriam, MD; Wolff, Gerhard, MD; Keck, Christoph, MD (October 2004). "Assisted reproductive techniques in patients with Klinefelter syndrome: A critical review". Fertility and Sterility. 82 (4): 775–779. doi:10.1016/j.fertnstert.2003.09.085. PMID 15482743.
{{cite journal}}: CS1 maint: multiple names: authors list (link) - ↑ Russell, Liane Brauch (9 June 1961). "Genetics of Mammalian Sex Chromosomes MOUSE STUDIES THROW LIGHT ON THE FUNCTIONS AND ON THE OCCASIONALLY ABERRANT BEHAVIOR OF SEX CHROMOSOMES". Science. 133 (3467): 1795–1803. doi:10.1126/science.133.3467.1795. PMID 13744853. S2CID 33813090.
- ↑ Centerwall WR, Benirschke K (1975). "An animal model for the XXY Klinefelter's syndrome in man: Tortoiseshell and calico male cats". American Journal of Veterinary Research. 36 (9): 1275–1280. PMID 1163864.
Other websites
[change | change source]- "Klinefelter Syndrome at the Open Directory Project". dmoz.org. Archived from the original on 24 June 2010. Retrieved 27 July 2010.