Open Source Simulation Software

A simple yet powerful mesh generator based on MATLAB/GNU Octave language, creating finite-element mesh from surfaces or arbitrary 3D volumetric images (such as MRI/CT scans) with fully automatic workflows.

Analysis software for MRS/NMR data. Allows processing and fitting to be performed in a fully automatic workflow.

This is a sophisticated & integrated simulation and analysis environment for dynamical systems models of physical systems (ODEs, DAEs, maps, and hybrid systems). It supports symbolic math, optimization, continuation, data analysis, biological apps...

Open-source CT/ Radiography simulation package. XRaySim works seamlessly with commercial CAD packages and performs highly detailed scan simulations, with virtual X-ray sources and detectors, simulating cracks/ inclusions etc. very easily

GIMIAS is a workflow-oriented environment for solving advanced biomedical image computing and individualized simulation problems, which is extensible through the development of problem-specific plug-ins. In addition, GIMIAS provides an open source framework for efficient development of research and clinical software prototypes integrating contributions from the Physiome community while allowing business-friendly technology transfer and commercial product development.

Our goal is to create an open source framework and toolset for modeling dynamic cellular network functions, and to develop a user community committed to using, extending and exploiting these tools to further our knowledge of biologic processes.

OpenCell is a user interface for working with CellML models. Features: * Integrate models made up of ODEs. * Supports CellML 1.0 and 1.1, allowing you to build complex models using imports. * Plot and edit graphs. * And more ...

The OpenCMISS-Zinc Library (opencmiss.org/zinc), or Zinc, is a software library for building interactive graphical modelling and visualisation applications. Models are represented in Zinc as mathematical fields defined over domains, including finite elements with support for high-order basis functions, complex parameter mappings and time variation, and image-based fields. Further fields can be defined by mathematical expressions and algorithms on existing fields, including image processing filters. Zinc model data structures are dynamic, supporting interactive applications which programmatically create, destroy and modify parts of models.

SimThyr is a continuous simulation program for the human pituitary-thyroid feedback control system. Applications of this program cover research, including development of hypotheses, and education of students in biology and medicine, nurses and patients.

Cell Electrophysiology Simulation Environment (CESE)

Census is a comprehensive cross-platform project manager and integration hub for NONMEM, the gold standard tool for model-based pharmacometric data analysis.

The Disease Simulation Framework (DiSiF) represents a spatial simulation environment for infectious viral disease spread. The framework currently embodies a very simple framework for simulation in 2D space with focus on SARS and the Common Flu.

It is a sofware to admin al things about a sportive club, from the trainig to the economy. The first step will take care of individual sports: athletics and cycling. Later we will support team sports like football, basket, handball or rugby.

The Health Manager Java SDK is an interface definition to connect wireless medical devices with a Java application. It includes also an implementation that simulates real devices and a sample application demonstrating the usage.

A deterministic pandemic influenza simulator. Computes the effect of interventions like antiviral treatment of cases and social distancing. To be used for pandemic preparedness planning by health care offices. OS-independent Java/SWT/RCP/Applet.

The Integrative Biology VRE is a web-based graphical user interface and repository that provides an environment where biological simulation experiments can be constructed without the need for any knowledge of unix, cluster computing, or shell scripting.

MASyV (Multi-Agent System Visualization) enables one to write agent-based models/cellular automata, eg. in C, visualize them in real time & capture to movie file with MASyVs GUI & message passing lib. Includes examples: Hello World, ants, viral infection

A topological data structure to handle 2D, surfaces and 3D simplicial meshes. This data structure is implemented in C++ using templates. It is based on Corner-Table and CGAL data structure.

Moved to: http://parkermills.github.io/phagetherapy/

SpiNet is a neural simulation tool for large spiking networks with highly heterogeneous synapses. Neurons are modelled as I&F units with dual exponential synaptic conductances. Complex network models can be easily built using the included tool NetBuilder

Synapsodel is an agent-based model of synaptic neurotransmission.

The Tomographic Image Reconstruction Interface of the Universite de Sherbrooke (TIRIUS) is a Qt-based user-interface software for reconstructing 3D images from data generated by real apparatus or generated by the GATE Monte Carlo simulator.

Tissue Simulation Toolkit is a two-dimensional library for the Cellular Potts Model (Graner and Glazier 1992; Phys. Rev. Lett. 69, 2013), which is increasingly used by computational biologists to study tissue patterning and developmental mechanisms.

PharmML is a markup for pharmacometrics markup language documented at http://pharmml.org/. This project provides a converter between the conventional mathematical infix notation and the math markup used by PharmML. The online version has been disabled. Please download for offline use.

runsbml - Pathway Simulation Tool emulates the dynamics of biological pathways by calculating concentrations of biochemical compounds at different times and conditions.