Best Clinical Decision Support Systems

Compare the Top Clinical Decision Support Systems as of November 2025

What are Clinical Decision Support Systems?

Clinical decision support systems (CDSS) are computer systems that assist clinicians in making decisions and providing evidence-based recommendations. CDSS utilize clinical data, patient information, and evidence-based guidelines to provide clinicians with information that can aid their decision-making process. They may also be used to alert clinicians about potential risks or possible issues involving a patient’s care. CDSS offer the potential for improved accuracy and quality of healthcare services. Compare and read user reviews of the best Clinical Decision Support systems currently available using the table below. This list is updated regularly.

  • 1
    Tamanu

    Tamanu

    Beyond Essential Systems

    Tamanu is a free and open-source EHR for low-resource and remote settings. Built around five fundamental principles outlined below, users also experience ongoing, active software development by a dedicated, full-stack team. Highly experienced delivery team, zero cost licensing, with optional service level agreements. An international community of support, and an intuitive, modern, flexible interface. Contribute to the global development community, with the security of no one ‘owning’ your code. Out-of-the-box for inpatients, outpatients, and community, no 3rd-party plug-ins needed. HL7 FHIR is compliant. Integrates with mSupply, mSupply Mobile, Tupaia, and DHIS2. ICD-10, GS1 compatible. Work online or offline with no limits, syncing whenever the internet is available, and no latency. Industry-standard encryption protocols, powerful security features, fit-for-purpose. At the hospital level, a desktop-enabled version allows a full suite of functionality.
    Starting Price: $35 per month
  • 2
    Napier Hospital Information System
    Napier Hospital Information System (HIS) is built using a modern technology stack. It is a web-based, integrated, multi-facility, multi-lingual, and scalable platform. Leading with innovation, Napier HIS leverages state-of-the art Artificial Intelligence powered by Napier AI Inside. Today, Napier works with leading hospitals in Asia, Middle East, and Africa. Leveraging such experience, Napier HIS allows providers to implement world-class process out-of-the-box. With a quarterly routine to feature updates alongside Napier's unique voice-of-customer (VOC) tool, clients are empowered to become partners in the product development journey. Napier HIS will help: 1. Management to plan and chart top-line growth more effectively 2. Financial officers to achieve healthier bottom lines 3. Administrators to manage resources and staff with greater efficiency 4. Integration with other clinical and ancillary solutions through a standards based approach to connectivity
  • 3
    Verana Health

    Verana Health

    Verana Health

    Verana Health is a real‑world data platform that transforms structured and unstructured electronic health record information into de‑identified, curated, disease‑specific data modules via its clinician‑informed and AI‑enhanced VeraQ population health data engine. Aggregating data from strategic partnerships with leading medical registries (including the American Academies of Ophthalmology, Neurology, and Urological Association), it encompasses over 20,000 clinicians and roughly 90 million patient records, providing near real‑time, high‑quality datasets to power real‑world evidence generation, clinical trial site and subject identification, clinician quality reporting, and medical registry management. Accessible through cloud services such as AWS Data Exchange and Amazon Redshift, the platform offers self‑service API access, an intuitive dashboard, and customizable cohort discovery tools, while advanced AI/ML algorithms, robust data quality assessments.
  • 4
    WinMed EHR
    WinMed™ EHR is an ONC 2015 Certified EHR system that empowers medical providers with the tools they need to accurately document and maintain compliance while providing quality patient care. Reach across the scope of your practice with the Analytics Dashboard. Gather information and provide critical guidance to both providers and management. Enhance clinical compliance and improve quality of care with automated system recommendations that guide and accelerate provider documentation. Our Family Practice module is devoted to comprehensive health care for people of all ages and is specifically designed with an emphasis on both acute and chronic care. Preventive care management is the cornerstone of our Internal Medicine module which includes Clinical Decision Support and Population Management as key features for helping to improve patient outcomes. Patient Check-In permits the user to easily see when a patient has arrived in the clinic.
  • 5
    RAAPID

    RAAPID

    RAAPID INC

    Over 15+ years, we have been the pioneers in building successful clinical NLP platforms & their applications that delivers high accuracy and precision rates. Our core capability is to interpret unstructured notes, accurately and at scale. Tried & tested on billions of diverse and real clinical notes & documents. Explainable AI with reasoning, context & evidence for output. Medical knowledge infused NLP with 4M+ entities & 50M+ relationships. Built using innovative Machine Learning (ML) & Deep Learning (DL) models. Leverage a foundation of rich ontologies & clinician-specific terminologies. We have the ability to understand, interpret and extract context & meaning from the messy, inconsistent, non-standardized data within medical documents. Our Clinical domain experts continuously infuse knowledge graphs into our NLP by mapping all the clinical entities and the relationship between them. So far, we have more than 4 million entities and 50 million relationships.
  • 6
    Posos

    Posos

    Posos

    Posos is a leading AI clinical decision support solution that helps clinicians tailor every prescriptions to the individual patient profile with up-to-date and multi-sources medical data. Posos diminish providers’ workload while ensuring better patient safety by cross-referencing evidence-based data sources with EHR patient's data to identify iatrogenic risks and reduce over-alerting. It provides potential drugs substitutions for the same or similar conditions that minimize side-effects. Posos provides API modules can be seamlessly integrated into EHR or e-prescribing softwares. It is successfully embedded into 15 EHR and EMR. It relies on the first native multilingual and SNOMED-structured medical database.
  • 7
    TrakCare

    TrakCare

    InterSystems

    If you could reimagine care, what would you do to improve the experience for patients, improve the workplace for clinicians, and create a sustainable future for your organization? Healthcare needs transformation. Begin with InterSystems TrakCare. Transforming Care The TrakCare unified healthcare information system is for organizations that want to make a difference in care by transforming care delivery and the patient experience. It is for organizations that are serious about digital transformation. TrakCare provides clinical, administrative, and financial information as a single source of truth for each patient in one electronic patient record. Built-in integration technology keeps it up to date with data from across your organization. Easier access to the information that matters. TrakCare’s clear presentation of clinically relevant information, powerful clinical decision-support capabilities, and insightful analytics and reporting enable its users to make informed decisions.
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