Compare the Top EDI Software in the USA as of November 2025

What is EDI Software in the USA?

EDI (Electronic Data Interchange) software is software that automates the exchange of business documents, such as invoices, purchase orders, and shipping notices, between companies in standardized electronic formats. It eliminates the need for manual data entry, reducing errors and improving the speed and accuracy of business transactions. EDI providers offer platforms and services that facilitate this seamless data exchange, integrating with existing ERP systems and ensuring compliance with industry standards. These providers also offer support for different communication protocols and data formats, enabling businesses to connect with various trading partners efficiently. By using EDI software and working with EDI providers, companies can streamline their supply chain operations, enhance collaboration, and reduce operational costs. Compare and read user reviews of the best EDI software in the USA currently available using the table below. This list is updated regularly.

  • 1
    EDI Power Reader

    EDI Power Reader

    EMS Healthcare Informatics

    EMS Healthcare Informatics provides effective middleware software, end-user-friendly EDI utilities, and custom application development for the healthcare industry. We specialize in the HIPAA transaction sets and focus on delivering actionable business data to the users. We have clients all over the United States, and in virtually every sub-industry of healthcare including those on the provider-side, the payer-side, as well as the extensive 3rd party community. EMS is a niche healthcare information technology firm that provides solutions for financial/administrative and clinical electronic transactions, full implementation and support services. EMS has been serving the needs of Healthcare Business and IT professionals since 1996. In addition to the EDI Power Tools Suite of readily deployable software utilities, EMS also develops custom applications tailored specifically to your needs: from unique single-purpose utilities, to Custom Enterprise Applications.
  • 2
    CustomsNow

    CustomsNow

    CustomsNow

    CustomsNow™ is focused purely on delivering trade solutions to drive costs out of your supply chain while improving compliance. Achieving 100% compliance at a fraction of the cost is your goal and our mantra. CustomsNow™, your direct filing solution, was built on the premise of superior customer service and the best, most secure and easy to use technology on the market. We are not just a technology company, rather a hybrid company that uniquely combines experience and technology in a format that delivers the importer the quickest return on investment at the lowest total cost of ownership. Our management team consists of professionals with diverse backgrounds, providing us with the breadth of experience fortifying our service model to meet the needs of an importer. Our pros have worked for the largest importers in the country, U.S. Customs and Border Protection, software companies, Customs Brokers and law firms.
  • 3
    SmartBorder

    SmartBorder

    SmartBorder

    Customs clearance technology for air, ocean, rail and truck imports and exports. Our intuitive applications allow you to manage your entire import/export operations with ease. And when you have questions - our knowledgeable support team led by licensed customs brokers will be there to back you up. Not every filer has the same operating procedures. SmartBorder is highly customizable and flexible to meet the most complex import requirements. We want to see our customers succeed. That means helping wherever we can – from answering technical questions to assisting a client with their first food entry. We have been developing and refining customs software for over 15 years. We stay one step ahead of the regulations so you can be sure you are compliant. SmartBorder was designed from the ground up to increase productivity and customs compliance for low and high volume brokers, carriers and importers.
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