Best ELN Software in the USA
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Compare the Top ELN Software in the USA as of November 2025
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What is ELN Software in the USA?
Electronic lab notebook (ELN) software provides researchers with the tools to optimize data collection and storage, transcription processes, information placement, and analysis operations. Compare and read user reviews of the best ELN software in the USA currently available using the table below. This list is updated regularly.
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LabWare LIMS
LabWare
14,000 laboratories. 125 countries. 98% customer satisfaction! Improve your lab's productivity, throughput, efficiency, data integrity, and compliance with LabWare's suite of laboratory automation solutions. LabWare offers flexible deployment options. Laboratories who are eager to deploy within 30 days can choose the cost-optimized + fully validated SaaS LIMS that contains best practice workflows. Laboratories that need a fully customizable enterprise-level LIMS/ELN can choose between flexible cloud or self-hosted deployment options. LabWare users enjoy world class features such as: lot management, sample management, stability management, environmental monitoring, instrument interfacing, workflows and dashboards, inventory management, COAs, barcoding, and much more! -
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eLabNext
eLabNext
eLabNext is dedicated to transforming laboratories worldwide with innovative digital solutions. We offer a comprehensive Digital Lab Platform (DLP), which integrates the Electronic Lab Notebook (ELN), Laboratory Information Management Systems (LIMS), machine learning, and AI. Our platform is designed to seamlessly integrate with your lab’s equipment and software, offering flexibility, security, and exceptional efficiency. By centralizing and optimizing all your research and process development workflows in a compliant environment, we empower researchers to focus on making ground-breaking discoveries. Our team of lab digitalization specialists is here to support you throughout your digitalization journey. eLabNext is a brand of Bio-ITech BV, part of Eppendorf Group. -
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Lockbox LIMS
Third Wave Analytics
A sample tracking, test result capture, and inventory management cloud LIMS for life science research, biotech/NGS, and industrial QC labs. Includes regulatory support for CLIA, HIPAA, Part 11, and ISO 17025. Nothing is more critical to a lab’s success than the quality, security, and traceability of samples. The Lockbox LIMS system provides robust sample management functionality to laboratory professionals, giving them full visibility on every aspect of a sample’s journey, from accessioning to long-term storage. LIMS analysis is about more than just tracking results- Lockbox’s multi-layered sample storage and location management functionality allows you to define your lab’s storage framework using a variety of location options: rooms, storage units, shelves, racks, boxes, and positions.Starting Price: $175/user/month -
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WeLIMS
WeLIMS
WeLIMS is the LIMS for small companies. Small companies might not have the budget for a LIMS but they still need to be organized and efficient in the Quality Control area. WeLIMS is a simple and efficient LIMS or Quality Control software. WeLIMS contains all you need to get started right now! Methods Management, Product Management, and Quality Control. You can say goodbye to your Notebooks and Excel spreadsheets! WeLIMS will take care of maintaining your product data and your QC data safely! With WeLIMS you can set the right level of authorization in your organization. Predefined roles for Product specifications management, Recipes management or Quality Control are already set up. Workflows make everyone collaborate efficiently and seamlessly.Starting Price: $30/month/user -
5
Labguru
BioData
Labguru is a secure, cloud-based Electronic Lab Notebook (ELN), LIMS and informatics platform which offers a complete solution for life science research and industry. It records and manages laboratory data and inventory, includes molecular biology tools and chemistry tools, enables automation of the lab, insight into lab data making labs run more efficiently. With Labguru, scientists can design experiments and workflows, capture structured and unstructured data, manage projects, and share their work. Customizable experiment templates, integration of protocols, SOPs, and other cutting-edge features help to increase data quality, streamline workflows and reduce costs. Labguru is available on desktops and mobile devices via the cloud. Labguru is part of Holtzbrinck Publishing Group and serves over 100,000 scientists worldwide from startups, universities, research institutes up to some of the largest pharma companies. -
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LIMSey
LIMSey
LIMSey is a web-based software designed to help engineering and mechanical test labs manage their entire process within one system. Assign and schedule resources, track job progress, manage ever-changing priorities, generate custom test reports, support regulatory audits and accreditation, manage equipment, maintenance, calibrations, training records, and more. All features, updates, and support are always included with no additional modules to buy. We focus on continuous improvement and regularly meet with our existing customers to plan and discuss new features. This collaboration helps drive the development of LIMSey to solve more and more real world problems faced by test labs. Most of our new features come directly from customer requests/. We're also very familiar with ISO / IEC 17025 and would love to help with your initial accreditation or renewal. Call us today at 512-537-9323 for a demo or free trial and start managing your entire lab from one place. -
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SciNote
SciNote
SciNote is a cloud-based electronic lab notebook (ELN) with built-in inventory, compliance, & team management tools. It is trusted by the FDA, USDA, European Commission, and 100K+ scientists in over 100 countries. Each premium plan comes with top-rated customer support, and a customer success manager who will work closely with you to ensure successful onboarding and implementation. SciNote provides a top-rated set of data management functionalities, such as inventory tracking & management, protocol & SOP management, compliance (CFR 21 part 11 & GxP), team management & collaboration, integrations and API, project management, safety & security of data and more. SciNote is based in Middleton, WI, USA, with offices in Europe. -
8
FindMolecule
FindMolecule
FindMolecule is an innovative online inventory and ELN platform for chemists and biologists. It is used in labs all around the world to improve their efficiency. Great for structure searches, barcode scanning, health & safety, orders management and much more. The electronic lab notebook is the most intuitive on the market. Our inventory management software and our ELN are very intuitive. FindMolecule is built to satisfy the requirements of the most security-sensitive organizations. Link your inventory to your electronic lab notebook in one click! Use our innovative drawing application to search your products by structure. No more excel files is requiered! Reduce errors and eliminate waste time of manual recordkeeping using barcodes. Use our chemical inventory management system and facilitate your work with our advanced features: the multiscan module, the structure and substructure search, the “Order” section including an impressive database. -
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GenoFAB
GenoFAB
Simplify your data collection processes by standardizing your operations. Integrate manual laboratory processes and computer-controlled instruments. Remove frictions in collaborations by giving your collaborators and services providers the data they need to do their job. Improve the reproducibility of your processes through standardization. Measure process reproducibility by comparing multiple repetitions of the exact same operations. Increase the statistical power of your experiments by producing more data points and reducing experimental errors. Increased statistical power is the difference between strong scientific results and anecdotal observations. Strong scientific results lead to stronger patent applications, higher impact publications, and accelerated development of better-performing products. Use the lab's dashboard to keep track of the work in process, the to-do list, and the list of backlogged requests.Starting Price: $2,995 one-time payment -
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Scilligence ELN
Scilligence
Scilligence ELN is a unified informatics platform that supports R&D effort across all scientific branches focusing on small molecules, mRNA, ADCs, DEL, and more. Our ELN provides an elegant solution to macromolecule work by leveraging the most advanced HELM implementations. With its purposeful design the Scilligence ELN is a platform that will help your lab elevate internal and external collaborative processes. Major Features • Large selection of user-vetted experiment templates • Proprietary indexing capabilities enable structure, HELM, and biosequence queries • Seamless integration with registration, inventory, and assay data warehouse • Proprietary informatics engine enables advanced HELM functionality and enhanced stereochemistry • Auto-extract information from flat files via our Data Reader technology for efficient data capturing and processing -
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LabCollector LIMS
AgileBio
LabCollector Lab Services Manager (LSM) is a cutting-edge network-based software solution that helps core facilities, laboratories, and biotechs. Simple and fully comprehensive, LabCollector LMS helps users manage a variety of useful day-to-day lab information. The solution comes with powerful modules, such as Strains & Cells Module, Plasmids Module, Sequences Module, Antibodies Module, Chemical Structures Module, Reagents & Supplies, Animals Module, Samples Module, Documents Module, Equipment Module, Address Book Module, and so much more.Starting Price: $2500.00/one-time/user -
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Xybion LIMS
Xybion
Xybion LIMS (formerly Labwise XD) is an all-inclusive LIMS, ELN, QMS, and DMS. Xybion LIMS drives lab workflows, instills consistency, improves data quality, and supports regulatory compliance with a complete laboratory management solution that connects with your operating systems with powerful laboratory information management and analytics. Xybion LIMS creates optimized workflows for the unique business needs of all regulated laboratories including research, diagnostics, quality control, stability studies, and more. -
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Labii ELN & LIMS
Labii
User-friendly, fully customizable Electronic Lab Notebook and Laboratory Information Management System. Adding a record of your work is as simple as completing a form. The form fields are fully customizable. A record consists of multiple sections. Complete the details of each section by typing or uploading your own files. Once records are added, they can be managed in the list view. Labii provides several default features to help you document, manage, and interpret your data. External data can be imported into Labii. Labii supports *.tsv, *.xlsx files. Labii does not have any request on the number of columns. You will have options to match the headers with fields in Labii. Please use the first row as headers. We received a lot of requests to create all different kinds of exports, and here is the updated version.Starting Price: $10 per 100G per month -
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Logilab ELN
Agaram Technologies
Logilab® ELN is Agaram’s time-tested Electronic Lab Notebook (ELN) solution designed to make laboratories completely paperless by enabling them to record, execute & store their tests, experiments, and lab tasks in a secure secure central database. Logilab® ELN is used by laboratories conducting tests & experiments across various scientific fields, and by researchers/organizations involved in project & product development in regulated and non-regulated industries. It ensures that laboratory organizations can aim to achieve higher productivity, better quality and compliance to various statutory compliance standards as well as Good Lab Practices (GxP) principles of data integrity. It helps labs with the following: • Simple interface to design lab templates for tasks & experiments. • Dynamic Inventory Management • User-configured dynamic reports & document creation. • Automate instrument data captureStarting Price: $30 / Month / User -
15
RSpace
RSpace
Researchers need tools that enable effective capture, management and sharing of research data. These tools, moreover, must integrate with data storage platforms/applications, other research tools, from enterprise chat to domain-specific tools like protocols.io, and data repositories. RSpace, the Connected electronic notebook, is the only ELN designed to fit seamlessly into the research data infrastructure at modern research-driven universities. As an early stage biotech you need to make rapid progress towards your next milestone. You also need to capture and organize your research data to lay the foundation for longer term IP protection and effective presentation of results to collaborators and investors. RSpace connects with research tools and with other components of the research infrastructure, to ensure the data that researchers produce is not only captured, but also properly managed and eventually made publicly available for others to view, query and re-use.Starting Price: $120 per user per year -
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LabCloud
LabCloud
LabCloud™ is dramatically changing the world of lab informatics. Integration is fundamental to a successful operation and effective research. LabCloud™ provides a fully integrated platform that allows R&D organizations to better manage research pipelines. Drive innovation while reducing operational expenditures, increasing laboratory compliance, and improving transparency. LabCloud’s Lab Notebook provides scientists with state-of-the-art tools in order to manage all of your information in one place. Full inventory management, item & instrument management, linked to Lab Notebook. Access to dozens of vendors, links directly to inventory, process orders and invoices, plus export to your accounting system. Access your data in a safe and compliant environment. LabCloud's unique software platform allows unparalleled control over data traditionally residing in isolated data silos. Having precise data control enables informed decision-making while ensuring compliance with industry standards.Starting Price: $7,500 per year -
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Ansys Cloud Direct
Ansys
Access Ansys Cloud Direct anywhere, anytime to obtain endless simulation capabilities compatible with most Ansys solvers. Engineering simulation has long been constrained by fixed computing resources available on a desktop or cluster. Ansys Cloud provides access to on-demand, cloud-based computing resources, including both interactive workstations and HPC clusters, for faster, high-fidelity results offering greater performance insight. Ansys Cloud increases simulation throughput by removing the hardware barrier. Ansys Cloud Direct is a scalable and cost-effective approach to HPC in the cloud. To leverage the combined benefits of cloud computing and best-in-class engineering simulation, Ansys partnered with Microsoft® Azure™ to create a secure cloud solution. Within Ansys Mechanical, Ansys Fluent, Ansys Electronics Desktop, Ansys SPEOS, Ansys Discovery, Ansys LS-Dyna, Ansys LST, Ansys CFX and Ansys Lumerical, you can easily access HPC in the cloud directly from the applications -
18
Docollab
Docollab
Research makes the world better, you deserve better research tools. LIMS and ELN: collaboration, project management, tasks, documents and spreadsheets with revision history and 100% compliant and backed up across all devices. Today's researchers hack their research process using standalone programs, note-taking on OneNote pasted into MS Word and Excel, sharing files via Dropbox, project management tools like Asana, then printing everything into a binder for PI and company compliance. Since 2007 Docollab has worked with leading organizations and institutions, under stringent workflow and compliance requirements, to create the most intuitive and robust platform for all your research needs whether you're an individual, small research team or a multi-national corporation. Intuitive structure to manage, maintain, and archive everything in one place (Electronic Lab Notebook). Structure your work, projects and files into folders and sub-folders.Starting Price: $25 per month -
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Benchling
Benchling
Legacy R&D software is a drain on scientific potential. It slows down R&D progress, scatters data across silos, and wipes out institutional knowledge. Benchling is the industry’s leading life sciences R&D cloud. Accelerate, measure, and forecast R&D – from discovery through bioprocessing – all in one place. A suite of seven natively unified applications that accelerate R&D at all levels. Codeless configuration, open integration, and dashboards tailored to your needs. Deep life science R&D and consulting expertise ensure ongoing success. Benchling is a unified R&D platform, so you spend less time entering and hunting for data, and more time working together to move your research forward. Scientists, managers, and executives can optimize R&D output with complete visibility into experimental context, program performance, and resource utilization. -
20
L7|ESP
L7 Informatics
L7 Enterprise Science Platform (L7|ESP®) is a unified platform that contextualizes data and eliminates business silos via process orchestration. It's a comprehensive solution that facilitates the digitalization of data and scientific processes in life sciences organizations. L7|ESP has native applications, including L7 LIMS, L7 Notebooks, L7 MES, L7 Scheduling, and more. It can integrate with existing third-party applications, lab instruments, and devices to capture all data in a single data model. It has a low-code/no-code workflow designer and hundreds of pre-built connectors to enable rapid time-to-value and end-to-end automation. By leveraging a single data model, L7|ESP enables advanced bioinformatics, AI, and ML to offer novel scientific and operational insights. L7|ESP addresses data and lab management needs in life sciences, particularly in: ● Research and Diagnostics ● Pharma and CDMO ● Clinical Sample Management Resource Center: l7informatics dot com/resource-center -
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Scispot
Scispot
Scispot powers life science labs with a unified LabOS™ platform, combining ELN, LIMS, SDMS, QMS, and AI in one configurable, no-code system. Built for CROs, Molecular Diagnostics, Pathology, Pharma QC, and Drug Discovery, Scispot streamlines sample management, inventory automation, and regulatory compliance. Connect with 200+ lab instruments and thousands of apps to eliminate data silos while maintaining FDA 21 CFR Part 11, GxP, GDPR, and HIPAA compliance. Scispot's AI tools transform experimental data into actionable insights, with flexible workflows that adapt as research evolves—without IT support. Trusted by 1000+ scientists globally, Scispot enables rapid deployment so teams focus on science, not administration. Accelerate discoveries, ensure compliance, and scale operations with a platform purpose-built for modern biotech innovation. -
22
Synthace
Synthace
The Synthace digital experiment platform lets you design powerful experiments, run them in your lab, then automatically build structured data. Synthace DOE is an adaptive design of experiments solution that makes sophisticated, multifactor experiments available to anyone–all defined, executed, and analyzed in one place. High throughput DOE automation and data isn't a pipe dream, it's already here. Unleash your equipment to work full pelt on the hardest problems you need to solve today, tomorrow, and every other day after that. Run V1 in the morning, then V2 after lunch. With Synthace's dynamic automation, you can update your experiments as often as you like, without (re)writing code: run your experiments this way, then that way, then back again. Act on your decisions with lightning speed. Automatically gather and structure your experiment designs, experimental data, and metadata, all in one platform. -
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Sapio ELN
Sapio Sciences
Sapio ELN is an electronic lab notebook that flexes to the needs of every scientific experiment by combining a built-in AI assistant, science-aware tools, no-code configurability, and powerful data integration and visualization into one unified platform. Its ELaiN chat assistant lets scientists create and configure experiments, manage consumables, integrate and query data, visualize results, optimize DNA sequences, and even generate custom code, all via natural-language conversation. The ELN includes an advanced molecular biology toolkit (CRISPR design, plasmid and compound design, PCR primer design, vector modification, genome browser), reusable experiment templates, free-form note taking, instrument integrations, real-time collaboration, and built-in statistical calculations. Science-aware searching lets users find structured and unstructured data, including substructure and similarity compound queries, and instantly generate interactive, scientific visualizations without SQL. -
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Labfolder
Labfolder
Drag & Drop all file formats into your electronic notebook and have your results side by side with your experimental procedure. Access your data anywhere in the world and download it from any computer. Import, preview, and extract Word and Excel files in Labfolder’s ELN. Work on these documents inside Labfolder while always keeping a copy of the original file. View images inside your lab notebook and take advantage of a vast array of annotation tools to always highlight what you want. Your annotations are stored on a separate layer, guaranteeing that your original image is always preserved. Your content does not need to be static once you create it. Drag and drop different elements within your entry to rearrange the layout. Labfolder is a browser-based ELN software and therefore compatible with all operating systems and most popular browsers. Access your data anywhere in the world and always be up to date with the latest developments of your research. -
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STARLIMS
STARLIMS
We simplify the complexity of your entire product lifecycle management process. Easy-to-use and adaptable to your organization’s needs, the STARLIMS brand of lab informatics solutions support the rapidly changing data management needs across your organization. Our laboratory information management solutions (LIMS software) can integrate with your current systems, while also identifying opportunities to improve processes so you can bring high quality and safe products to market faster. -
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Alchemy Cloud
Alchemy
Alchemy is an enterprise SaaS company helping to modernize the $1 trillion global specialty chemicals industry. Alchemy helps specialty chemicals companies accelerate their formula development and commercialization processes, be more responsive to customers, and grow top line revenue. With Alchemy's Chemistry Acceleration Software, customers increase lab capacity, accelerate chemistry innovation, and grow sales. From concept to chemistry, Alchemy accelerates product development and improves service delivery for chemicals and materials companies. Whether you’re working on fundamental R&D, new products or helping customers get the most from your current products, Alchemy accelerates your lab, sales and service processes so you can speed time to revenue on new product development, decrease lab cost per sale and improve customer responsiveness. Industry-specific software to accelerate chemistry development, sales and service. -
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CDD Vault
Collaborative Drug Discovery
With CDD Vault, you can intuitively organize chemical structures and biological study data, and collaborate with internal or external partners through an easy to use web interface. Start your free trial and see first hand how easy it is to manage drug discovery data. Tailored for you Affordable Scales with your project team(s) Activity & Registration * Electronic Lab Notebook (ELN) * Visualization * Inventory * APIs * Secure Online Hosting -
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Signals Notebook
Revvity Signals
Signals Notebook has a modern user interface like the ones on all your personal apps, the need for training is negligible. You will be up and running in no time. That’s part of the reason Signals Notebook is the electronic lab notebook of choice for companies as to whether it’s a team of 4-5 research scientists to the largest biotechs and pharmaceutical companies in the world. Flexibility and breadth to support wide range of workflows now and in the future — including both chemistry, biology, formulations, analytical sciences, and materials sciences. Over 1 million scientists at 4000 organizations count on Signals Notebook to help them streamline their workflows. Structured data capture with APIs and interfaces for integration with instruments, in-house systems, and databases. -
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ScienceDesk
ScienceDesk
ScienceDesk data automation demystifies the use of artificial intelligence in materials sciences. A practical tool for your team to add and apply the newest AI algorithms on an everyday basis. Customizable properties, universal identifiers, QR-codes and a powerful textual-numeric search engine that links sample and experimental data. ScienceDesk is an innovative platform for scientists and engineers to interact with, collaborate on and obtain insights into their experimental data. Unfortunately, the potential of this asset is not fully exploited due to the variety of data formats and the strong dependence on experts to manually extract specific information. The ScienceDesk research data management system solves this problem by combining documentation and data analysis in a cleverly-engineered data structure. Researchers and scientists are empowered by our algorithms to gain total control of their data. They can not only share datasets, but even the analysis know-how. -
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StackWave
StackWave
StackWave's Laboratory Information Management System (LIMS), Electronic Laboratory Notebook (ELN), and Scientific Data Management System (SDMS) are modern, flexible, and innovative software solutions that will increase the overall efficiency of your laboratory. Let the team at StackWave help you automate all of your tedious scientific processes so your team can focus on what really matters. StackWave's laboratory software is the perfect fit for labs in any industry and of any size. Our solutions support a diverse range of processes. We've worked with teams at fledgling biotechs, large pharmaceutical companies, and everything in between. Leveraging the latest in web, database, and software technologies, the StackWave LIMS is the most modern laboratory information management system available. Built on StackWave’s proven software infrastructure, the StackWave LIMS provides the flexibility, reliability, and performance to meet your most demanding information management challenges.