Compare the Top SPC Software in the USA as of November 2025

What is SPC Software in the USA?

Statistical process control (SPC) software allows manufacturing companies to streamline the management, comparison and analysis of statistical data in order to optimize performance and make predictions. Compare and read user reviews of the best SPC software in the USA currently available using the table below. This list is updated regularly.

  • 1
    Shoplogix Smart Factory Platform
    Shoplogix is a smart, scalable platform trusted by manufacturers worldwide for over 20 years. It transforms real-time machine and production data into actionable insights, helping teams uncover hidden losses and drive rapid ROI. Features include intuitive visual dashboards, integrated analytics, and real-time alerts for fast, informed decisions. Shoplogix connects to any machine type, tracking downtime, scrap, throughput, and setup stages. Operators and managers can quickly spot issues, launch action plans, and improve efficiency on the fly. With built-in continuous improvement tools and seamless scaling from one line to multi-plant operations, Shoplogix empowers your team to eliminate bottlenecks, boost OEE, and achieve lasting operational excellence.
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  • 2
    MasterControl

    MasterControl

    MasterControl

    Bringing breakthrough products to market in highly regulated industries can feel like an endless series of trade-offs. MasterControl's software simplifies GxP workflows so you never have to sacrifice quality for cost or innovation for regulation. Complete and connected meets fast and flexible. From quality event management to document control and integrated training - MasterControl Quality Excellence transforms your quality data and processes into a competitive advantage. Modernizing your manufacturing operations starts with modern software. From work orders to work instructions and production records (EBR or eDHR) to logbooks, MasterControl Manufacturing Excellence is the simplest way to digitalize manufacturing.
    Starting Price: $25,000 / 1st year
  • 3
    QAD Redzone
    Redzone has taken the food, beverage, and CPG manufacturing markets by storm with a digital production system that was purpose built for lean manufacturing and continuous improvement. By empowering frontline workers as their productivity engine, customers regularly post and sustain 30+% productivity uplifts following their first 90-day deployment. Typical Outcomes: - Rapid double-digit productivity improvements - A collaborative workforce engagement system that reduces turnover - A culture of continuous improvement driven by your workers and sustained over the long term With specific modules for production, quality and maintenance all built on a social/mobile platform for everyone-to-everyone collaboration, you'll connect all levels of the business to catch concerns before they become issues and get them fixed!
  • 4
    Dot Compliance QMS

    Dot Compliance QMS

    QMS for Life Sciences

    Dot Compliance provides the industry’s first off-the-shelf QMS solution – ready to deploy from day one, with little to no setup required, while also incorporating industry best practices and standards that address the latest global regulatory requirements. Powered by the Salesforce.com platform, our solutions enable life science organizations to quickly digitize their quality and compliance processes including Document Management, Training Management, Change Control, CAPA, Customer Complaints. Compliant with 21 CFR part 11, EU-Annex 11 and support ISO 9001, 13485, 14971, 27001 & MORE! Processes included: ▶ Document Management ▶ Training Management ▶ Quality Event Management ▶ CAPA Management ▶ Change Management ▶ Complaint Management ▶ Audit Management ▶ Supplier Quality Management ▶ Risk Management ▶ Design Control ▶ Deviations/Non-conformances ✔ Seamless Install ✔ Cost Effective ✔ One-Stop-Shop
    Starting Price: $10,000 / Annually
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