David Baker, PhD
Director, Institute for Protein Design
Investigator, Howard Hughes Medical Institute
Henrietta and Aubrey Davis Endowed Professor of Biochemistry, University of Washington School of Medicine
Adjunct Professor, Genome Sciences, Bioengineering, Chemical Engineering, Computer Science, and Physics, University of Washington
Mohamad Abedi
Postdoc
mabedi
Mohamad is designing proteins to understand and manipulate cell signaling networks
Stephanie Adaniya
Grad Student
sadaniya
Green Ahn
Postdoc
greenahn
Green is designing proteins to modulate cellular processes involved in cancer.
Han Raut Altae-Tran
Postdoc
altaeth
Han is studying nucleic acids and design methods
Kim Anjarwalla
Undergrad
jka43
Kim is working on small molecule binders this summer.
Samaira Bakshi
Undergrad
samaira
Samaira is designing de novo protein circuits
Pooja Bandawane
Grad Student
banda14
Pooja is working on solubilizing membrane proteins for therapeutic and vaccine design, and designing a ph-switch.
Roman Barth
Postdoc
robarth
Roman is designing novel enzymatic molecular motors.
Magnus Bauer
Postdoc
magnusb
Magnus is exploring the design of kinases and protein-based inhibitors to decode and manipulate cellular logic.
Riti Biswas
Grad Student
ritib
Riti is working on antibody design to accelerate biologic therapeutics R&D.
Yang Bo
Postdoc
yangbo
Yang is designing proteins for tissue-specific drug delivery.
Julia Bonzanini
Grad Student
jbonz
Julia is making proteins that can specifically bind to peptide-MHC molecules for cancer immunotherapy.
Rafi Brent
Grad Student
rib7
Rafi is working on deep learning methods for antibody structure prediction and design.
Jasper Butcher
Grad Student
jbutch
Lazlo Camou
Undergrad
lcamou
Lazlo is working on de novo beta-barrel nanopores for small molecule sensing.
Adam Chazin-Gray
Postdoc
achazing
Adam is using protein design tools to develop novel antimicrobial therapeutics and combat multidrug resistant bacterial pathogens.
Wei Chen
Postdoc
wchen108
Wei is designing proteins to modulate gene expression
Jie Chen
Grad Student
jiechen7
Anqi Chen
Postdoc
achen918
Anqi is interested in generating very specific proteases.
Ganyu Chen
Postdoc
gchen321
Ganyu is designing new protein motors.
Hojae Choi
Grad Student
hojaec
Hojae is working on sequence-specific protease design
Juyoung Choi
Grad Student
juyoung1
Juyoung is designing protein nanomachines — including protein cilia and shape-morphing materials — powered by light-driven protein motors.
Jungho Chun
Postdoc
jhchun
Jungho is designing proteins that modulate immune cells to differentiate into specific cell stages and elicit desired immune responses.
Nathaniel Corley
Grad Student
ncorley
Nate is developing deep-learning methods for all-atom protein structure prediction and design, with an emphasis on enzymes
Alexis Courbet
Acting Instructor
acourbet
Alexis is a protein nanomachine designer and AI-based protein design researcher, exploring the field from first principles to translation.
Brian Coventry
Staff
bcov
Brian is trying to understand the forces that stick proteins together
Kate Crawford
Postdoc
katecraw
Kate is developing modular enzymes to produce new-to-nature products.
Wenzhao Dai
Postdoc
wendai
Elliot Delfosse
Grad Student
delfo
Helen Eisenach
Grad Student
heisen
Helen is developing deep learning-based design methods for self-assembling symmetric nanomaterials.
Steven Engelbretson
Undergrad
sengel6
Steven is designing de novo small molecule binders over the summer
Declan Evans
Postdoc
dme5188
Declan is designing enzymes for reactions not observed in Nature
Marc Exposit
Grad Student
mexposit
Marc is designing de novo cytokines
Timo Fluegel
Postdoc
fluegelt
Timo is designing acyltransferases to synthesize amide and ester bonds.
Katya Frazier
Undergrad
frazikat
Maximilian Gantz
Postdoc
mgantz
Max is designing enzymes for sustainable chemistry and CO2 fixation
Shilong Gao
Postdoc
sggao
Shilong is designing proteins to extend the chemical space accessible to biology.
Mariana Garcia Sanchez
Staff
marigs
Matthias Gloegl
Postdoc
mgloegl
Matthias is designing de novo antagonists and agonists for treatment of autoinflammatory disease and cancer.
Inna Goreshnik
Staff
ig1983
Shivansh Goyal
Postdoc
sgoyal24
William Grubbe
Postdoc
wgrubbe
Will is designing conditionally-active cytokines and other protein therapeutics.
Laura Guerrero
Grad Student
lgue26
Laura is designing peptide-MHC scaffolds to enable the understanding of peptide-specific disease associations.
Ella Haefner
Grad Student
ellahaef
Ella is designing proteins to modulate protein homeostasis.
Nikita Hanikel
Postdoc
nhanikel
Nikita is working on the design of de novo metalloproteins
Stephanie Hanna
Grad Student
hannas1
Xi He
Grad Student
hexi
Ricardo Heinzmann
Visitor
rheinz
Jonathan Held
Visitor
jheld
Jonathan is working on cytokine engineering.
Shingo Honda
Postdoc
shhonda
Shingo is designing asymmetric protein assembly aided by a peptide scaffold.
Yang Hsia
Staff
yhsia
Yang is interested in designing protein and protein-adjacent bio-materials across different length scales (nano- to macro-scale).
Evelyn Huddy
Staff
thuddy
Evie is making biomineral compartments and proteins that can be assembled sequentially
Abbas Idris
Grad Student
aidris1
I design programmable assembly and disassembly of protein nanoparticles
Zhazira Iskakova
Undergrad
jazira
Jihun Jeung
Grad Student
jeung
Jihun is interested in designing metalloenzymes and developing deep learning-based computational tools.
Shirley Ji
Grad Student
xji3
Indrek Kalvet
Staff
ikalvet
Indrek is designing new enzymes based on catalytic cofactor binding.
Max Kazman
Grad Student
mkazman
Sebastian Kenny
Postdoc
skenny97
Kenny is designing minibinder proteins to perform targeted protein degradation for novel therapeutic applications.
Ryan Kibler
Postdoc
rdkibler
Ryan is designing proteins for purifying non-biological compounds of industrial interest
Chan Johng Kim
Acting Instructor
chanjkim
Chan is designing cytokine mimics to boost anti-cancer immunity with fewer side effects, activating only in tumor-specific environments
Paul Kim
Grad Student
ptkim
Paul is working on generative models for design of DNA-binding-proteins, with the eventual goal of optimizing for specificity.
David Kim
Staff
dekim
Donghyo Kim
Postdoc
donghyo
Donghyo is designing de novo enzymes using deep learning methods.
Brianne King
Postdoc
brking
Brianne is designing enzymes for small molecule catalysis and bioremediation.
Yakov Kipnis
Staff
yak
Yakov is working on computational enzyme design.
Jeremy Koob
Postdoc
jkoob
I am engineering new-to-nature enzymes to tackle urgent environmental crises – currently focused on plastic upcycling.
Rohith Krishna
Postdoc
rohith
Rohith is developing neural networks for structure prediction and design.
Aditya Krishnakumar
Grad Student
aditya20
Aditya is designing de novo cytokines for autoimmune therapies
Andrew Kubaney
Grad Student
akubaney
Andrew is developing deep learning models for RNA sequence design and protein-DNA specificity prediction.
Riko Kusumi
Visitor
rk225
Paul Kwon
Grad Student
pkwon2
Paul is fine-tuning deep learning methods for protein-mineral interface design and incorporating interfaces into larger hybrid materials.
Seulhoo Lee
Postdoc
seulh
Seulhoo is developing metalloenzymes, including for plastic degradation.
David Lee
Grad Student
davidsl
David is designing a modular protein toolkit to generate specific cell signaling outcomes.
Drew Levitt
Grad Student
levitt
Yanjing Li
Grad Student
yanjing
Jia Liang
Grad Student
jyliang
Caixuan Liu
Postdoc
lcx425
Caixuan is designing proteins that bind to intrinsically disordered peptide targets.
Bingxu Liu
Postdoc
bxliu
Bingxu is working on transforming living system evolution logic from try-and-error to rational design.
Edward Lopatto
Postdoc
elopatto
Edward is designing proteins to treat bacterial infections
Peik Lund-Andersen
Grad Student
peikl
Peik is designing redox enzymes and electron transport proteins for artificial photosynthesis
Meg Lunn-Halbert
Grad Student
mlunn1
Meg is a BPSD graduate student in the King and Baker labs. She is working to improve vaccine efficacy using de novo protein design.
Janani Maheswaran
Undergrad
jananiii
Janani is working on redesigning cytokines of the IL-12 family
David Mai
Postdoc
damai
David is interested in tools to direct cell state and function.
Nora McNamara-Bordewick
Grad Student
noramcb
Nora is working on using protein design to create new therapeutics that target "undruggable" proteins and allow for new delivery modalities
Amelie Medeiros
Undergrad
amedeiro
Amelie is designing transmembrane beta-barrel proteins for ion transport.
Ljubica Mihaljevic
Postdoc
ljubim
Lj extracts intact native proteins from membranes and precisely reinserts membrane proteins made from scratch using de novo protein design
Joe Min
Grad Student
joemin
Joe is interested in developing methods to redesign native enzymes to combat the effects of climate change.
Noah Mitton
Undergrad
nmitt
Noah Mitton is a undergraduate researcher focusing on de novo binder design.
Stanislav Moroz
Grad Student
stanim
Aiko Muraishi
Grad Student
aimura
Aiko is developing all-atom generative models for symmetric enzyme designs.
Edin Muratspahic
Postdoc
edinm2
Edin is working on de novo design of binders targeting G protein-coupled receptors (GPCRs)
Hung Nguyen
Undergrad
hoangn28
Annika Philomin
Grad Student
aphilo
Annika is designing transmembrane beta barrel proteins for polymer membranes and ion separation
Yuliya Politanska
Grad Student
ypolit
Yuliya is working on the computational design of DNA binding proteins with a goal of developing de novo transcription factors.
Harley Pyles
Staff
pylesh
Harley is designing and characterizing proteins to control the formation of minerals
Jason Qian
Postdoc
jq01
enzyme design
Tingli Qian
Grad Student
tlqian
Xiangli Qu
Postdoc
xiangliq
Xiangli is interested in designing protein binders to modulate the function of membrane proteins like GPCRs
Riley Quijano
Grad Student
rnquijan
Riley is using both DNA-binder design and enzyme design to make de novo nucleases capable of cutting new recognition sites.
Shawn Ralyn
Grad Student
ralyn
Shawn is working on de novo enzyme design for sustainable chemical bioproduction
Nicole Roullier
Staff
roullnl
Nicole is optimizing yeast workflows to better identify useful de novo proteins
Antonia Ruder
Visitor
aruder2
Shayan Sadre
Grad Student
ssadre
Shayan is interested in designing binders to modulate protein homeostasis.
Saman Salike
Grad Student
ssalike
Stephanie Sansbury
Postdoc
ssans
Steph is engineering nanoparticle-compatible designs to facilitate efficient delivery of intracellularly-targeted therapeutic cargos
Christina Savvides
Grad Student
savvides
Christina is interested in designing immunomodulators to treat autoimmune diseases.
DeJenae See
Grad Student
dlsee
DeJenae works on antibody and nanobody design.
Enisha Sehgal
Grad Student
esehgal
Enisha is designing DNA binding proteins to modulate gene expression and edit genomes.
Shajesh Sharma
Grad Student
shajesh
Shajesh is designing new proteins that bind and sense small molecules
Kathryn Shelley
Postdoc
ks427
Kathryn is designing proteins that undergo light-driven conformational change.
Hao Shen
Postdoc
shenh2
Hao is designing self-assembling protein filament nanomaterials
Alexander Shida
Grad Student
ashida
Alex is combining conformational dynamics with enzyme design
Hojeong Shin
Postdoc
hojshin
Hojeong is designing proteins to modulate immune cells in a tumor-specific manner
Shirin Shivaei
Postdoc
sshivaei
Ellen Shrock
Postdoc
eshrock
Ellen is studying determinants of immunogenicity.
Abhishek Singh
Postdoc
as393
Abhishek is exploring how to create highly asymmetric protein assemblies with precise control over shape and size.
Zihao Song
Grad Student
zhsong
Zihao is interested in designing a synthetic proteome and an artificial cell
Ria Sonigra
Grad Student
rias04
Ria is working on designing transmembrane proteins for biosensing applications
Belen Sotomayor
Postdoc
belenst
Belen is working on the de novo design of carbohydrate-active enzymes for therapeutic applications
Chase Suiter
Postdoc
ccsuiter
Chase is developing methods for high-throughput functional characterization of de novo proteins.
Eric Sun
Grad Student
suneric
Eric is developing and testing methods for antibody design.
Avi Swartz
Grad Student
azswartz
Avi is designing new photosystems for artificial photosynthesis
Mia Switzer
Staff
miaswit
Alan Talavera
Undergrad
atalav2
Tabitha Tcheau
Grad Student
ttcheau
Kirsten Thompson
Grad Student
kathomps
Kirsten is working on de novo protein and cellular cancer immunotherapies.
Tuscan Rock Thompson
Grad Student
tuscant
Tuscan is developing design methods for noncanonical peptides.
Long Tran
Grad Student
lhtran
Eva Trapido
Undergrad
evat20
Dionne Vafeados
Staff
vafeados
Preetham Venkatesh
Postdoc
preetham
Preetham is designing sequence-specific proteases
Kelly Wang
Grad Student
keyiwang
Xingzao Wang
Postdoc
xwang257
Anny Wang
Undergrad
annyw1
Anny Wang is a summer intern working under Stephanie Sansbury to develop a transcriptional activation-based readout for cytosolic delivery.
Carl Wang
Postdoc
carlwang
Carl is designing enzymes to clean up forever chemicals
Yujia Wang
Acting Instructor
yujiaw21
Yujia is interested in designing enzymes to address challenges in biotechnology and organic synthesis.
Weijin Wang
Postdoc
wewang
Weijin is designing enzymes with abiotic activities
Roni Weissman
Grad Student
ronimw
Roni is working on designing new nanocage modalities for delivery.
Jonas Wilhelm
Postdoc
jonaswil
Jonas is designing enzymes that catalyze new-to-nature reactions
Gde Bimananda Mahardika Wisna
Postdoc
gwisna
Bima is interested in designing de novo oligomeric protein motors fueled by enzymatic reactions.
Seth Woodbury
Grad Student
woodbuse
Seth is designing de novo (metallo)enzymes from quantum chemistry theozymes for diverse catalytic and photocatalytic applications.
Kejia Wu
Postdoc
kejiawu
Kejia is on method development for binding peptides/intrinsically disordered regions, and functionalizing the binders.
Chuanyun Xu
Postdoc
chuanyxu
Chuanyun is designing modular transmembrane components for sensing, manipulating, and transporting.
Avery Yang
Grad Student
averyyy
Avery is designing C-C bond-forming enzymes
Tracy Yu
Postdoc
tracyy2
Tracy is working on developing bone-mimetic materials via hydroxyapatite mineralization proteins.
Yuyang Zhang
Visitor
yyzhang1
Jingyi Zhu
Postdoc
jyz1
Jingyi is designing ligand-binding proteins for fluorescent biosensors