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A WRAP for biology’s greasiest problem
A new way to solubilize membrane proteins without detergents using computationally designed “WRAPs,” making some of biology’s most challenging proteins easier to study.
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Programming proteins with viral geometry
Computationally designed proteins can self-assemble into large, tunable nanocages inspired by viral capsids.
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Mohamad Abedi Receives Michelson Prize: Next Generation Grant
Mohamad is advancing innovative immunology research and therapeutic design.
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Jonas Wilhelm and Chuanyun Xu receive WRF Postdoc Fellowships
Jonas and Chuan are building new climate solutions and tools for neurobiology.
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Building calcium channels from scratch
Even complex biochemical functions that remain only partially understood can now be built from first principles using AI.
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Building protein on/off switches
Medicines that can be rapidly toggled on and off could help end the trade-off between creating powerful drugs and safe ones.
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Helping immune cells spot disease
New peptide-MHC binding proteins promote targeted immune activation.
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Hitting ‘undruggable’ disease targets
Generative AI can be used to create proteins that bind disordered proteins and peptides with atomic precision.