I gotta say, I love this show. It was a little slow coming out of the gate, but I have been watching every one and I think it's awesome. I'm a Chelsea Handler fan, but I don't like watch Chelsea Lately every day... but I love that this kind of show exists at E! And I've never seen a show that blurs the lines of reality quite this way, which is interesting -- not everyone is a great actor, but the fact that they are real people playing themselves is fun enough to make up for it.
It's not for everyone, but it makes me laugh... and it reminds me of Larry Sanders Show, just meaner and more real. I have fun watching these people because they sound like real people, like ridiculous conversations I have with my friends, and it feels natural, like people talking, like in The Office.
I guess if you don't like these people, or if you just want more Chelsea Lately, this show won't be your cup of tea... but it works for me and I've been telling my friends about it. I hope it keeps going, it's way better than the other crap E! runs. I only watch E! for The Soup and Chelsea Lately... and now After Lately. Keep up the good work.