Billed as the final entry in what is called The Unicron Trilogy (with the first two shows being Armada and Energon), Cybertron is a show I saw some of, but not all due to Cartoon Network placing it in a timeslot that is after the Adult Swim block goes off the air.
In this series, the destruction of Unicron has created a black hole that threatens to swallow Cybertron, the population evacuates to Earth after one of the Autobots, Landmine, is warped there by Vector Prime during a battle with the Decepticons. Now in hiding and with air of three human kids, Coby, Bud, and Lori, the Autobots must collect the four Cyber Planet Keys, one on Earth and the other three on different planets with their own Transformers, to save Cybertron from destruction. However, the Decepticons also seek the keys, but instead of saving Cybertron, they seek to use it to destroy the Autobots and rule the galaxy.
This anime can get a bit bumpy. While this was connected to Armada and Energon in America, for its Japanese release as Transformers Galaxy Force, it was made as a different continuity, thus requiring a lot of additional scenes and script edits for the English dub in order to connect it to the past two series. Also, while some of the voice actors do return, some of them end up giving their characters foreign accents (Jetfire now speaks in an Australian accent, while Red Alert, who was in Armada, but absent from Energon, is made British), a move possibly done to show Transformers can be different in more ways than how they look. The show mixes traditional animation for the human characters with the CGI used for the Transformers, and it makes it work. Coby, Bud, and Lori serve as replacements for Rad, Carlos, Alexis, and Kicker (which is due to the Japanese version being its own universe), and thankfully, they are better than Kicker, and even have more of a role aiding the Autobots in some situations. And while the script has some continuity errors, they are well written, and the show does explore other planets (like Jungle Planet, a planet with Transformers who adapted animals as their alternate mode). While not as good as Armada, Transformers Cybertron fixes the many mistakes that Energon (considered the worst of the trilogy in my book) made.