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Coronavirus

Coronaviruses are a group of related RNA viruses that can cause respiratory infections in humans and birds ranging from mild to lethal. They also cause diarrhea in cows and pigs and hepatitis and encephalomyelitis in mice. Coronaviruses have a positive-sense single-stranded RNA genome and envelope with club-shaped spikes, and include genera such as alphacoronavirus, betacoronavirus, gammacoronavirus, and deltacoronavirus. There are currently no vaccines or antiviral drugs to prevent or treat human coronavirus infections.

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0% found this document useful (0 votes)
20 views2 pages

Coronavirus

Coronaviruses are a group of related RNA viruses that can cause respiratory infections in humans and birds ranging from mild to lethal. They also cause diarrhea in cows and pigs and hepatitis and encephalomyelitis in mice. Coronaviruses have a positive-sense single-stranded RNA genome and envelope with club-shaped spikes, and include genera such as alphacoronavirus, betacoronavirus, gammacoronavirus, and deltacoronavirus. There are currently no vaccines or antiviral drugs to prevent or treat human coronavirus infections.

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Coronavirus

This article is about the group of viruses. For the disease involved in the ongoing COVID-19
pandemic, see Coronavirus disease 2019. For the virus that causes this disease,
see Severe acute respiratory syndrome coronavirus 2.

Orthocoronavirinae

Transmission electron

micrograph of Avian coronavirus

Illustration of a SARS-CoV-2 virion[2]

  Red: spike proteins (S)

  Grey: lipid bilayer envelope

  Yellow: envelope proteins (E)

  Orange: membrane proteins (M)

Virus classification

(unranked): Virus
Realm: Riboviria

Kingdom: Orthornavirae

Phylum: Pisuviricota

Class: Pisoniviricetes

Order: Nidovirales

Family: Coronaviridae

Subfamily: Orthocoronavirinae

Genera[1]

 Alphacoronavirus
 Betacoronavirus
 Gammacoronavirus

 Deltacoronavirus

Synonyms[3][4]

 Coronavirinae

Coronaviruses are a group of related RNA viruses that cause diseases


in mammals and birds. In humans and birds, they cause respiratory tract infections that can
range from mild to lethal. Mild illnesses in humans include some cases of the common
cold (which is also caused by other viruses, predominantly rhinoviruses), while more lethal
varieties can cause SARS, MERS, and COVID-19. In cows and pigs they cause diarrhea,
while in mice they cause hepatitis and encephalomyelitis. There are as yet
no vaccines or antiviral drugs to prevent or treat human coronavirus infections.
Coronaviruses constitute the subfamily Orthocoronavirinae, in the family Coronaviridae,
order Nidovirales, and realm Riboviria.[5][4] They are enveloped viruses with a positive-sense
single-stranded RNA genome and a nucleocapsid of helical symmetry.[6] The genome size of
coronaviruses ranges from approximately 26 to 32 kilobases, one of the largest among RNA
viruses.[7] They have characteristic club-shaped spikes that project from their surface, which
in electron micrographs create an image reminiscent of the solar corona, from which their
name derives.[8]

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