Biochemistry Page 1 of 9
Biochemistry Page 1 of 9
          a. 40oC                     b. 60oC                   c. 37oC                d. 10oC                              a. energy requiring reaction b. energy producing reaction c. no energy is involved
38. Glucose is stored in the liver as:                                                                                      d. energy is absorbed
          a. galactose                b. glycogen               c. lactose             d. fructose              56.   Which of the following is a characteristic of lipid?
39. The enzyme conformation adapts to the incoming substrate in                                                             a. zwitterions          b. amphiphilic          c. hydrophobic          d. hydrophilic
          a. Lock and Key theory b. Induced fit theory c. competitive inhibition                                57.   It is a condition that results when sugar level is below normal
          d. noncompetitive inhibition                                                                                      a. hypoglycemia              b. hyperglycemia            c. ketonuria                 d. uremia
40. The process of converting glucose into glycogen is called:                                                  58.   An example of globular protein
          a. gluconeogenesis          b. glycogenesis       c. glycolysis          d. glycogenolysis                        a. albumin                   b. collagen                 c. fibrin                    d. silk
41. All are pyrimidine bases except:                                                                            59.   Complementary base pairs in the DNA double helix are bonded by
          a. guanine                  b. cytosine               c. uracil                    d. thymine                     a. H-bond               b. ester bond           c. Van der Waals            d. dipole- dipole
42. Glucose, amino acid and fatty acid enter the citric acid cycle by their conversion into:                    60.   Which nitrogen base is not found in DNA?
          a. pyruvate                 b. acetyl CoA         c. acetoacetyl CoA d. palmitic acid                             a. thymine                   b. cytosine             c. uracil                    d. guanine
43. A hormone which stimulates glycogenesis:                                                                    61.   An organic cofactor in an enzyme
          a. insulin                  b. glucagons          c. epinephrine         d. vasopressin                           a. vitamins             b. coenzymes            c. a and b              d. none of these
44. Chemicals extracted from organism such as bacteria and can inhibit growth or destroy other                  62.   At what stage of glucose oxidation is most of the energy produced?
microorganism:                                                                                                              a. glycolysis           b. aerobic stage        c. glycogenesis         d. glygenolysis
          a. antibiotic               b. enzyme             c. hormone             d. vitamins                  63.   The best known building blocks of RNA and DNA are:
45. The gland or tissue that regulates the blood glucose level:                                                             a. purines                   b. pyrimidines              c. fatty acids               d. a and b
          a. parathyroid              b. thyroid                c. pancreas                  d. adrenal         64.   It is responsible for the storage and transmission of genetic information
46. Which vitamin is formed in the body by exposure to ultraviolet irradiation or sunlight?                                 a. adenine              b. RNA                  c. DNA                  d. nucleic acid
          a. vitamin A                b. vitamin B              c. Vitamin C                 d. vitamin         65.   Build up of urea in the kidney is called
47. Excess vitamin A and D is stored in the body, but excess vitamin B and C is readily excreted.                           a. ketonuria            b. glycemia             c. uremia               d. all of these
What property shows this?                                                                                       66.   The transfer of genetic information from DNA by the formation of mRNA
          a. vit. C and B are water-soluble b. vit. A and D are fat –soluble c. both a and b                                a. transcription        b. translation          c. trans-amination          d. replication
          d. none of these                                                                                      67.   What is the end product of electron transport chain?
 48. It is the entire genetic make up of an organism                                                                        a. oxygen                    b. hydrogen             c. carbon dioxide            d. water
          a. gene                 b. anticodon              c. codon                   d. mutation              68.   The energy producing reaction
 49. The vitamin which is used in the prevention of degenerative changes in the central nervous                             a. metabolic                 b. catabolic                c. anabolic              d. all of these
system:                                                                                                         69.   It is the molecule that directs the activity of the cells
          a. vit. A                   b. vit. B complex         c. vit. C                    d. vit. D                      a. DNA                       b. RNA                      c. nucleoproteins         d. hormones
50. It is a model which best explains the enzyme-substrate action:                                              70.   The sugar involved in DNA
          a. lock and key             b. molecular              c. VSEPR                     d. Kreb                        a. ribose                    b. pentose                  c. deoxyribose               d. xylose
51. The activation of pepsinogen requires:                                                                      71.   The common metabolic pathway is
          a. pepsin                   b. NaOH                   c. enterokinase              d. HCl                         a. glycolysis           b. beta oxidation            c. Kreb’s cycle              d. glucogenesis
52. DNA is primarily found in the                                                                               72.   Rosenheim’s test is used to detect the presence of:
          a. cytosol          b. nucleus/mitochondria c. cell wall        d. endoplasmic reticulum                          a. ethanolamine         b. choline              c. cholesterol          d. glycone moiety
 53. It is the enzyme which hydrolyzes starch to dextrin and maltose:                                           73.   Detects the presence of alpha amino acids:
          a. catalase                 b. amylase                c. pepsin                    d. lactase                     a. Biuret               b. Molisch              c. Ninhydrin            d. Hopkins-cole
 54. A synthetic DNA is called
          a. replicated DNA           b. plasmid            c. Gene           d. recombinant DNA                74. The process of producing fats from acetyl Co-A is called:
 55. Hydrolysis of ATP is an                                                                                            a. glycolysis         b. lipogenesis        c. glycogenolysis                  d. glucogenesis
Biochemistry                                                                                               Page 3 of 9
75. The following are test reagents to detect the presence of amino acids, except:                                93. ID test to detect the presence of glycogen:
        a. Grignard’s           b. Xanthoproteic       c. Millon-Nasse              d. Sakaguchi                          a. phloroglucinol            b. molisch             c. iodine              d. seliwanoff
76. The condition that lowers the pH of the blood due to starvation is called                                    94. The only sugar readily forms insoluble osazone crystals:
        a. acidosis                  b. alkalosis                c. hyperglycemia          d. glycosuria                  a. lactose                   b. sucrose                  c. mannose                 d. sucrose
77. The substance responsible for the emulsion of fats is:                                                       95. Important structural material found in the exoskeletons of many lower animals:
        a. HCl                       b. bile acids               c. pepsin                    d. trypsin                  a. chnondroitin              b. heparin                  c. hyaluronic acid         d. chitin
78. Hubl’s solution if used to ascertain degree of:                                                              96. Hydrolysis of osazones produce:
        a. saturation                b. unsaturation             c. peroxidation              d. acidity                  a. phenylhydrazones          b. ozones              c. sugars          d. none of the above
79. IUPAC name of acrolein:                                                                                      97. General term for a group of polysaccharides present on the primary cell wall:
        a. pentenal                  b. propenal                 c. hexanal                   d. acetone                  a. xanthan                   b. mucilage                 c. pectin              d. carageenan
80. The positive indication for the presence of glycerol in acrolein test:                                       98. Specific test for galactose, due to the formation of highly insoluble crystals:
        a. yellow colored solution                     c. silver mirror formed in the test tube                           a. phenylhydrazine test      b. fermentation             c. mucic acid          d. molisch
        b. black markings in filter paper              d. play of colors from blue to shades of red               99. Type of RNA which serves as template for the amino acid sequence being synthesized:
81. Cerebrosides are positive in the following tests, except:                                                             a. mRNA                 b. tRNA                c. rRnNA           d. none of the above
        a. Molisch         b. Biuret               c. Lassaigne’s           d. none of the above                 100. Positive indication for Anthrone test:
82. Osmic test is used to detect the presence of ____ in lipids:                                                          a. purple ring               b. blue-green color         c. effervescence       d. yellow ppt
        a. metals                    b. prostate groups          c. unsaturated groups       d. glycerol         101. Differentiating test between helical and linear polysaccharides:
83. The most sensitive chemical test to detect the presence of cholesterol:                                               a. Molisch                   b. iodine                   c. Schweitzer          d. fermentation
        a. Liebermann-Burchard                     c. Formaldehyde-sulkfuric acid                                102. The difference between Benedict’s and Barfoed’s test reagent lies in:
        b. Salkowski reaction                      d. Colorimetric spectrophotometry                                      a. sequestering agent used        b. active component used        c. pH of the solution
84. The following are phopholipids, except:                                                                               d. alkali used
        a. plasmalogen               b. lecithin                 c. cephalin                  d. choline         103. Hydrolytic product of chitin:
85. A mixed triglyceride contains:                                                                                        a. iduronatet       b. acetylgalactosamine c. acetylglucosamine d. glucuronic acid
        a. three similar fatty acids esterified with glycerol        c. three different fatty acids              104. Glucose and fructose are:
             esterified with glycerol                                                                                     a. anomers              b. epimers             c. geometric isomers        d. allosteres
        b. two similar fatty acids esterified with glycerol          d. all of the above choices                 105. The complementary strand of CGACCTTGATCGACGTCGA:
86. The central compound found in the structure of sphingolipids:                                                         a. TCGTTCCAGCTAGTAACTAG                                  c. AGCAAGGTCGATCATGATC
        a. glycerol             b. sphingosine         c. ceramide              d. phosphocholine                         b. GCTGGAACTAGCTGCAGCT                                   d. ATCAAGGTCGATCATGATC
87. Lipid whose specific test is the Furter-Meyer test:                                                          106. Alkaline bismuth reagent is used to detect the presence of:
        a. tocopherol                b. retinal             c. sphingomyelin        d. cerebroside                        a. polysaccharides b. disaccharides            c. reducing sugars      d. glycitols
88. Precipitate of _____ indicates the presence of phospholipids in the lipid sample:                            107. Action of dilute alkali on sugars:
        a. ammonium phosphomolybdate                   c. phosphorus triiodide                                            a. dehydration          b. hyperconjunction c. hydrolysis         d. tautomerization
        b. phosphorus periodate                        d. phospho-ammonium sulfate complex
89. The following are glycolipids, except:                                                                       108. The following are the components of DNA nucleosides, except:
        a. globosides                b. phosphatides        c. gangliosides              d. cerebrosides                 a. phosphoric acid         b. sugar                   c. adenine                d. cytosine
90. The parent compound of phospholipids:                                                                        109. Central dogma concept wherein the RNA molecule is used as template for the synthesis of
        a. glycerol        b. phosphatidic acid        c. ethanolamine          d. none of the above             DNA molecule:
91. A non-pentose sugar which is also positive for Tollen’s phloroglucinol test:                                         a. transcription      b. translation    c. mutation           d. none of the above
        a. galactose            b. glucose             c. fructose              d. cellobiose                    110. The following proteins are present in egg white, except:
92. The reagent present in Molisch test which is responsible for the dehydration reaction:                               a. ovomucin           b. ovoglobulin          c. albumin              d. osseomucoid
        a. sodium canbonate          b. magnesiumstearate        c. sulfuric acid             d. NaOH            111. Anaerobic glycolysis occurs in the:
Biochemistry                                                                                                     Page 4 of 9
          b. neutralization of chyme           d. destruction of bacteria                                       164. When starches are heated , they produce:
147. Transamination is:                                                                                                 a. sugars                b. glycogen             c. dextrins                  d. disaccharides
          a. conversion of amino acid to hydroxy acid             c. conversion of amino acids to keto          165. Check the incorrect statement:
               acids                                                                                                    a. ribose is an aldopentose                      c. galactose is an aldohexose
          b. loss of ammonia from amino acid                      d. formation of ammonium salt from                    b. maltose is a ketohexose                       d. glucose is an aldohexose
               ammonia                                                                                          166. The reducing property of sugars is due to this group:
148. The lipid that is converted to Vitamin D12 upon irradiation:                                                       a. aldehyde              b. nitro                c. carboxyl             d. methyl
          a. ergosterol          b. glycerol            c. cholesterol             d. all of the above          167. The monosaccharide most rapidly absorbed from the small intestine is:
149. The metabolic degradation of hemoglobin takes place principally in:                                                a. glucose               b. fructose             c. mannose              d. galactose
          a. the reticuloendothilial system        c. the white blood cells                                     168. A condition known as atherosclerosis results as an accumulation in the blood vessels of
          b. the red blood cells                   d. the liver cell                                                    a. calcium               b. pathogens            c. cholesterol          d. ketones
150. The amino acid that is an important precursor of hemoglobin is:                                            169. Ketoses can be differentiated from aldoses by this test:
          a. alanine             b. proline             c. glycine                 d. cysteine                          a. Molisch’s test        b. Benedict’s test      c. Seliwanoff’s test       d. Tollen’s test
151. Serine is converted to ethanolamine by the removal of:                                                     170. The clinical test for the determination of cholesterol:
          a. oxygen              b. ammonia             c. carbon dioxide          d. a carboxyl group                  a. Liebermann-Burchard b. Salkowski                   c. both a and b d. none of the above
152. Ninhydrin gives a blue coloration with:                                                                    171. Concentrated dehydrating acids change monosaccharides to:
          a. proteins            b. carbohydrates       c. amino acids             d. simple sugars                     a. simple sugars         b. saccharic acids c. furfurals d. uronic acids           e. aldaric acids
153. Which is the monomer unit of proteins?                                                                     172. A mucopolysaccharide which possesses an anticoagulant property:
          a. amino acid         b. monosaccharide            c. fatty acid              d. purine                       a. pectin      b. hyaluronic acid      c. heparin     d. chitin e. chondroitin sulfate
154. The proteinase that is found mostly in gastric juice of young animals:                                     173. Which of the following is the test for reducing sugars for urine?
          a. rennin              c. steapsin            e. none of the above                                            a. Benedict’s test       b. acrolein test             c. Biuret test     d. Brown Ring test
          b. pepsin              d. ptyalin                                                                     174. Lactose can be differentiated from fructose by:
155. Conjugated proteins which are a combination of amino acids and carbohydrates:                                      a. Mucic acid test b. Barfoed’s test         c. Fehling’s test d. Iodine test e. Tollen’s test
          a. nucleoproteins      b. glycoproteins       c. phosphoproteins         d. chromoproteins            175. Polymers that are responsible for the metabolic capabilities and morphology of organisms are:
156. Gamma decarboxylation of aspartic acid produces:                                                                   a. carbohydrates         b. proteins        c. polysaccharides           d. nucleic acid
          a. alanine             b. asparagines         c. glutamic acid           d. glycine                   176. The product obtained from the partial hydrolysis of collagen:
157. Rotation of polarized light is caused by solutions of all of the following amino acids, except:                    a. myosin b. gelatin              c. actin       d. fibrinogen       e. thrombin
          a. alanine             b. glycine             c. leucine                 d. valine                    177. The main carbohydrate of the blood is:
158. It is a disease due to protein deficiency:                                                                         a. D-fructose            b. D-glucose       c. mannitol                  d. sorbitol
          a. Kwashiorkor         b. diabetes            c. albuminuria             d. jaundice                  178. A normal value of glucose in the blood:
159. Which of the following amino acids is not essential in mammals?                                                    a. 100 to 200 mg% b. 80–120 mg%                  c. 50–75 mg%            d. 200–300 mg%
          a. phenylaline         b. lysine              c. tyrosine                d. methionine                179. Butter becomes rancid upon exposure to air due to formation of:
160. The following are examples of chromopretien, except:                                                               a. acetic acid           b. butyric acid         c. formic acid          d. propionic acid
          a. chlorophyll         b. hemoglobin          c. cytochromes             d. heparin                   180. The cholesterol molecule is:
161. For the amino acid cysteine, choose the appropriate description of its side chain:                                 a. an aromatic ring b. a straight chain acid           c. a steroid     d. A tocopherol
          a. acidic              b. basic               c. aromatic                d. sulfur-containing         181. Which of the following is a phospholipid?
162. Which of the following amino acids has a net positive charge at physiologic        pH?                             a. glycogen              b. prostaglandin        c. sphingomyelin             d. oleic acid
          a. cysteine            b. glutamic acid       c. lysine                  d. valine                    182. The passage of the end products of digestion from the small intestine into the blood stream:
163. Sickle cell anemia is the clinical manifestation of homozygous genes for an abnormal                               a. metabolism b. digestion             c. absorption       d. oxidation       e. reduction
hemoglobin molecule. The mutational event responsible for the mutation in the beta chain is:                    183. Endocrine gland that is a small oval body situated at the base of the brain:
          a. crossing over       b. insertion           c. deletion                d. point mutation                    a. hypophysis            b. pancreas             c. adrenal              d. none of the above
Biochemistry                                                                                                   Page 6 of 9
184. Cellular elements of the blood devoid of nucleus:                                                               202. Which of the following is NOT an ID test for proteins and amino acids?
         a. RBC                  b. WBC                   c. thrombocytes          d. all of the above                        a. Ninhydrin                 b. Bial’s                   c. Biuret          d. Xanthoproteic
185. Is the sum total of all activities directed towards the maintenance of life:                                    203. What vitamin deficiency causes pellagra?
         a. catabolism      b. anabolism c. metabolism             d. photosynthesis e. fermentation                          a. riboflavin           b. thiamin              c. pantothenic acid       d. nicotinic acid
186. This substance accumulates in the muscles as a result of vigorous exercise:                                     204. All are pyrimidine base, except:
         a. muscle glycogen         b. amino acids        c. lactic acid          d. glucose                                  a. cytosine                  b. thymine                  c. uracil               d. guanine
187. A common intermediate of metabolism of carbohydrates, fatty acids and amino acids is:                           205. The sugar that yields only glucose when hydrolyzed is:
         a. glycerol b. acetyl CoA c. acetoacetate                d. oxaloacetate     e. acetylcholine                        a. galactose                 b. maltose                  c. fructose            d. sucrose
188. The principal site of glucose production in the human body is the :                                             206. Which is not a B-complex vitamin?
         a. blood                b. liver                 c. pituitary gland      d. small intestine                          a. folic acid                b. nicotinic acid           c. riboflavin          d. ascorbic acid
189. The major buffer of the extracellular fluid:                                                                    207. The following sugars are aldohexoses except:
         a. bicarbonate-carbon dioxide b. amino acids c. phosphate                d. none of the above                        a. fructose                  b. galactose                c. glucose              d. mannose
190. Separates from cells when blood is coagulated:                                                                  208. All the amino acid below contain sulfur, except:
         a. fibrinogen      b. plasma           c. serum       d. thrombin        e. none of the above                        a. cystine                   b. methionine               c. cysteine            d. glycine
191. Glycolipids found in high concentrations in the brain and nerve cells especially in the myelin                  209. The following are essential fatty acids, except:
sheath:                                                                                                                       a. oleic acid           b. linoleic acid            c. linolenic acid       d. arachidonic acid
         a. lecithin             b. cephalins             c. cerebrosides             d. sphingolipids               210. This test detects the presence of two or more peptide bonds:
192. Alcohol in the body is :                                                                                                 a. Ninhydrin                 b. Fehling’s                c. Tollen’s            d. Biuret
         a. oxidized to CO2 and HOH                       c. excreted by kidneys                                     211. This vitamin easily undergoes oxidation:
         b. excreted mainly by lungs                      d. excreted by large intestine                                      a. vitamin A                 b. vitamin C                c. vitamin B12         d. vitamin B1
193. Which of the following tissues contains the enzyme glucose-6-phosphatase and is able to                         212. The end product of anaerobic glucose metabolism is:
supply glucose to the blood?                                                                                                  a. pyruvate                  b. lactate                  c. carbon dioxide         d. water
         a. heart           b. brain            c. liver       d. none of the above                                  213. The inactive form of an enzyme is sometimes called:
194. Complete digestion of all foodstuffs occurs in the :                                                                     a. zymogen                   b. holoenzyme               c. apoenzyme           d. coenzyme
         a. large intestine      b. stomach c. mouth          d. small intestine      e. pancreas                    214. Photosynthesis is a process involved in the manufacture of:
195. This compound is not a normal constituent of urine:                                                                      a. carbohydrates             b. fats                c. proteins             d. all of the above
         a. sodium chloride            b. albumin              c. urea            d. uric acid                       215. The major extracellular cation is:
196. Decomposition of carbohydrates brought about by the action of enzymes liberating                  ethyl                  a. potassium                 b. sodium                   c. calcium            d. iron
alcohol and CO2:                                                                                                     216. Which sugar will not give a red precipitate with cupric oxide when heated with Benedict’s
         a. fermentation         b. adsorption       c. detoxification       d. hydrolysis                           solution?
         e. saponification                                                                                                    a. glucose                   b. sucrose                  c. maltose             d. fructose
197. Blood clotting can be prevented by:                                                                             217. Night blindness is a symptom of a deficiency in this vitamin:
         a. sodium chloride            b. potassium chloride        c. sodium citrate                                         a. vitamin A                 b. vitamin C                c. vitamin B           d. vitamin D
198. This hormone elevates blood sugar concentration:                                                                218. The activation of pepsinogen requires:
         a. insulin                    b. progesterone              c. estrogen        d. glucagons                           a. NaOH                      b. bicarbonate              c. acetic acid         d. HCl
199. Deficiency in this vitamin causes red blood cell fragility:                                                     219. Nucleosides upon hydrolysis will yield:
         a. vitamin A                  b. vitamin K                 c. Vitamin D       d. vitamin E                           a. adenine + phosphate b. quanine + phosphate c. histones + ribose
200. The end-product in the hydrolysis of glycogen is:                                                                        d. cytosine + ribose
         a. galactose                  b. mannose                   c. glucose          d. arabinose                 220. Protein digestion starts in the:
201. In which form is glucose stored in the liver?                                                                            a. mouth                     b. small intestine     c. stomach         d. large intestine
         a. glycogen                   b. glucose (unchanged) c. sucrose              d. starch                      221. Major form of utilizable energy in all cells:
Biochemistry                                                                                                 Page 7 of 9