PATHOLOGY

VOLUME 1
Cell adaptation, injury and death
1 Infarct and gangrene (2) *2
2 . Dystrophic calcification (2)
3 Liquefactive necrosis and coagulative necrosis (2)
4 Fatty change (2) *3
SNecrosis and apoptosis (2) *4
6. Dystrophic and metastatic calcification (2)*5
Free radical injury (2) *4
& Reversible and irreversible injury (2) *2
9Apoptosis (2)
L0.Hypertrophy and hyperplasia (2)
JACoagulative necrosis (2)
j2Describe morphological patterns of tissue necrosis with their causes and
examples (4)
13.Mechanism of fatty change of liver (2)
J4Dry and wet gangrene (2)
(15.Hypertrophy and atrophy (2)

Inflammation and repair

Enlist chemical mediator of acute inflammation and describe arachidonic
acid metabolites in detail. (4)
Transudate and Exudate (2) *4
3 Healing of primary and secondary intention (2) *5
AChemotaxis (2)
5Define inflammation and describe cellular events of acute inflammation
(4) *4
Cytokines (2) *3
(7. Granuloma and granulomatous tissue (2)
Factors affecting healing ofwound (2) *2
9. Vascular events of acute inflammation (2)
J9.Define inflammation and describe vascular events in acute inflammation
(4)
 Hemodynamic disorders
tPathogenesis of renal edema (2)
2. Hypovolemic shock (2)
3. Red and white infarct (2) *2
4. Septic shock (2)
S Arterial and venous thrombus (2) *3
6. Describe the pathogenetic factors involved in thrombus formation (4)
7. Fat embolism (2))
8. Hyperemia and congestion (2)
9. Mechanism of ascites and portal hypertension (2)
10.Air embolism (2)

Genetic disorders
1. Klinefelter syndrome (2) *3
2. Turner syndrome (2) *2
3 Barr bodies (2)
4. Autosomal dominant and autosomal recessive disorders (2)
5. Down syndrome (2)

Immunopathology
1. Sentinel lymph node and its importance (2) Beat
2 T and B cells (2)
3/Type Il hypersensitivity (2)
4. Granuloma (2) *2 9fahiu- S Kej
SXype I hypersensitivity reaction (2)
6/Amyloid stains (2) *2
KHypersensitivity reaction I and IV (2) *2
Z Primary and secondary amyloidosis (2)
9. Atopy (2)
1OSago spleen (2)
Define hypersensitivity. Classify hypersensitivity reactions with

examples. (4)
2Primary amyloidosis (2)
13/1ype TV hypersensitivity (2)
JAGranulomatous inflammation (2) *2

h|la mtio » h
 anu

*2
J5.Type I and III hypersensitivity (2)
i6.AA and AL amyloid (2)
17.Mechanism of evolution of granuloma ( 2 ) 9ah. F r efe

18.Opportunistic infections in AIDS (2)

19.Primary tuberculosis (2)
for establishing HIV
of transmission of HIV infection and
tests
20Modes
infection (2)
M,Cell mediated and humoral immunity (2)
Secondary amyloidosis (2)
23.Classification of amyloidosis with examples (3)
Pie Ai rdo
24.Causes of splenomegaly and hypersplenism (2).
25.

Neoplasia
X. Define neoplasia and describe
metastasis of tumours (4) *2
*8
Benign and malignant tumour (2)
of spread of tumour (4)
Define metastasis and describe pathways
Paraneoplastic syndrome (2)*2
SMetaplasia and dysplasia (2)
*2

6umour suppressor genes (2)

Tumour metastasis (2)
metastasis in neoplasia (4)
&Discuss the mechanism of invasion and
*2
9. Carcinoma and sarcoma (2)
10Teratoma (2) *2
(11)Major genetic properties of cancer (2)
M.Role of Epstein Barr virus (2)
.Tumour markers (2) *2
tumour (2)
4.Routes of spread of malignant
metastasis (2)
J5.Mechanism of

Infectious diseases

1. Tuberculous and typhoid ulcer (2)

Ghon complex (2) *2
*7.
3AL and BT leprosy (2) tuberculosis
Primary and secondary (2)
B. Primary complex (2)
Environmental and nutritional diseases
1. Kwashiorkor and marasmus (2)

Disorders of platelets
diopathic thrombocytopenic purpura (2) *4
Blood transfusion reactions (2) *2
4. Non hemolytic blood transfusion (2)
5. Reverse cross matching (2)
6. Acute hemolytic reaction in blood transfusion (2)
7. Investigations in bleeding disorders (2)
8. Megakaryocyte (2)
9. Transfusion transmitted infection (2)
18.Von Willebrand factor (2)
11.Criteria for selection of a blood donor (2)
12.Acute transplant rejection (2)
(13PTI (2)
14.Bombay blood group (2)
kAcute and chronic ITP (2)
6.Causes ofthrombocytopenia (2)
TClassify bleeding disorders and enumerate the lab investigations (3)
L&:DIC (2)
IT 8 TT

WBC disorders
YClassification of acute myekoid leukemia (2)
2. Leukopenia (2) *2
Multiple myeloma (2)
4 Peripheral blood picture of chronic mveloid leukemia (2)
SPhiladelphia chromosome (2) *2
6Lab diagnosis of multiple myeloma (2) *4
7. Causes of leukocytosis (2)
&Lab diagnosis of acute leukaemia (2) *2
CML and myeloid leukemoid reaction (2) *3
 M L and ALL (2)
iReticulocyte count (2)
12.Leukemia and leukemoid reaction (2) *3
3Myeloblast and lymphoblast (2) *3
HLeukemoid reaction (2) *3
JCauses of eosinophilia (2)
16.Reed Sternberg cell (2) *2
17.Hodgkin lymphoma and non-Hodgkin lymphoma (2)
of AML
+8.Classify AML and describe peripheral blood smear morphology
(4)*2
19Eosinophilia (2)
20CML (2)
(21.Bence jones proteins (2) *2
22.Cytochemistry in acute leukemia (2)
23:FAB classification of AML (2) *3
24.Myelodysplastic syndrome (2)
25.Lab findings in CML (2)
lab findings (2)
26.Causes of leukemoid reaction and its characteristic
2Classification of Hodgkin's lymphoma (2)
(28.Role of cyiochemistry in diagnosis of leukemia (2)
-Burkitt's lymphoma (2)

RBC disorders
Classify anemia and lab diagnosis ofthalassemia (4)
2. Causes and lab diagnosis of microcytic hypochromic
anemia (2) *2
3. Lab diagnosis of sickle cell anemia (2) *2
anemia in detail (4) *3
AClassify anemia and describe megaloblastic
. Coombs test (2) *2
6. Sickle cell anemia (2) *5
T. Lab diagnosis of iron deficiency anemia (2) *4
8. Erythrocyte sedimentation rate (2) *66
9 Enumerate causes of macrocytic anemia. Describe peripheral blood
picture and bone marrow finding in case of megaloblastic anemia (4)
*2

10 Thalassemia and iron deficiency anemia (2)

Direct and indirect Coombs test (2) *2
2Classify anemia and describe iron deficiency anemia in brief (4) *2
13Bone marrow picture of megaloblastic anemia (2)
14Lab diagnosis of thalassemia (2)
 and thalassemia minor (2)
5halassemia major
6Polycythemia vera (2) *2
B o n e marrow aspiration (2)
d8.Hereditary spherocytosis (2) thalassemia major (4)
anemias. Write lab diagnosis of
9.Classify hemolytic
20.Hereditary spherocytosis (2)
21.Anticoagulants used in hematology (2)
22.Rh system (2) anemias
anemias and write about the lab diagnosis of hemolytic
23.Classify
4)
24.Clinical features of thalassemia major (2)
25.Hemophilia A (2) *2
.Pancytopenia (2) *2
deficiency
27Describe the clinical features and laboratory diagnosis ofiron
anemia
28.G6PD deficiency (2)
29.Significance of ESR (2)
30.Haemophilia (2)
Kathogenesis of hereditary spherocytosis and enumerate causes of
intracorpuscular haemolytic anemias (3)
32.Lab diagnosis of megaloblastic anemia (2) *3
33.Anticoagulants used in hematology lab (2)
4B thalassemia major (2)
35, Indications of bone marrow examination (3)
36-Causes of aplastic anemia (2)
 VOLUME 2
CVS
Describe briefly the morphology, lab diagnosis and complications of
myocardial infarction (4) *2
2Achoffnodule (2)
Complications ofinfective endocarditis (2)*3
SCe-1ar)
A Describe risk factors and morphology of atherosclerosis (4)
SVegetation of rheumatic and acute infective endocarditis (2) * 7
. Lab diagnosis of myocardial infarction (2) *3
,7Aransmural and subendocardial myocardia infarct (2)*2
S.Subacute bacterial endocarditis (2)
Complications of atherosclerosis (2)
19Morphological changes in rheumatic heart disease (2) *2
J.Write risk factors and investigations of myocardial infarction (4) *3
J2Short note on rheumatic heart disease (2)
JBDiscuss risk factors, gross, microscopic features and complications of
atherosclerosis (4)
JAComplications of MI (2)
5Pathogenesis of atherosclerosis (3)
+6.Complications of atheromatous plaques (2)

Lung
XBroncho pneumonia and lobar pneumonia (2) *5 e tg- ° )
Extrinsic and intrinsic bronchial asthma (2)
l g -29)
3Small cell carcinoma of lung (2) *4
Bronchiectasis (2) *2
SEmphysema and chronic bronchitis (2) *2 see 29
Military tuberculosis (2)
KAetiopathogenesis of bronchogenic carcinoma (2)
8 . Define emphysema. Enumerate types and write in brief about centriacinar
emphysema (4)
Risk factors for carcinoma lung (2)
40.anacinar and centriacinar emphysema (2) *5
MPathogenesis of bronchial asthma (2) *2
12Morphology of lobar pneumonia (2)
 H3.Asbestosis of lung (2)
14.Emphysema (2) *2
Atypical pneumonia (2)
16.Coal worker's pneumoconiosis (2)
7Lung abscess (2)
JTypes of bronchogenic carcinoma (2)
9.Etiopathogenesis of emphysema (2)
Liver and Gallbladder
. (2) > 1K
Alcoholic cirrhosis
2Aab investigation in Hep B (2) *2 .bo'a
3. Hepatocellular jaundice (2)
4. Causes and morphology of liver cirrhosis (2)AK
Describe briefly the pathogenesis and lab diagnosis of hepatitis B
infection (4) *5 Kolbin
6. Hemolytic and obstructive jaundice (2) *3
7. Complications of gall stones (2) *2
S. Fatty liver (2) *2 AK
. Define, classify and describe pathogenesis of cirrhosis ofliver (4)
10.Gall stones (2) *3
HDescribe antigenic structure of hepatitis B and its laboratory diagnosis (4)
Short note on portal hypertension (2) Robbins
(13Pathophysiology of viral hepatitis (2)
14.Hepatocellular and obstructive jaundice (2) *2
15Causesand morphological changes in fatty liver (3) AK
16.Formation of gall stones (2)

GIT
Ulcerative colitis and Chrons disease (2) *6
2-Classification and morphology of carcinoma of stomach (2)
3. Benign and malignant gastric ulcer *3
4. Enumerate ulcerative lesions of small intestine. Write etiopathogenesis
and morphology of chrons disease (4)
5. Complications of acute appendicitis (2)
6. Discuss the role ofH. pylori in gastric lesions (4) *3
7. Pathology of intestinal tuberculosis (2)
8. Barret's esophagus (2) *5
9. Ulcerative colitis (2)
10:Difference between gastric ulcer and malignant ulcer of stomach (2)
 HTuberculous and typhoid ulcer (2) *2
12.Describe gross and microScopic features of gastric adenocarcinoma (4) *2
13.Ulcers in intestine (2)
14.Chron's disease (2)
15.Complications of peptic ulcers (2)
16.Tuberculous and amoebic ulcers (2)
17.Differentiate between gastric ulcers and duodenal ulcers (3)
18.Etiopathogenesis and morphology of peptic ulcer (3)

Kidney
Nephritic and nephrotic syndrome (2) *8
2 . Classify glomerular diseases. Write morphological feature of post
streptococcal glomerulonephritis (4) *3
Wilms tumour (2) *5
Describe pathogenesis and lab diagnosis of rapidly proliferative
glomerulonephritis (RPGN) (4) *4
Malignant and benign nephrosclerosis (2) *3
Morphology of chronic pyelonephritis (2) *2
.Renal cell carcinoma (2) *2
Describe the morphologic and laboratory features of acute post
streptococcal glomerulonephritis (4) *2
Lab investigation in chronic pyelonephritis (2)
JOMinimal change glomerulonephritis (2)
11.Renal stones (2)
2Define nephrotic syndrome. Explain its cauaes and pathophysiology (4)
13.Describe mechanism of glomerular injury in glomerulonephritis (3)
14.Hypertensive nephropathy (2)
13Urinary findings of chronic pyelonephritis (3)
ooo
IgA pathy
Female genital tract
C I N of cervix (2)
Teratoma (2) *3
XMature and immature teratoma (2)
Leiomyoma and leiomyosarcoma (2) h Beol wle C nK)
5 ciomyoma (2) *2
bDysgerminoma (2)
Cervical intraepithelial neoplasia (2)
8. Struma ovari (2)
.Etiopathogenesis and morphology of cervical cancer (2)
 and mucinous cystadenoma of ovary (2)
6.Serous
Choriocarcinoma (2)
12.Classification of ovarian tumours (2)
13Germ cell tumours of ovary (2)
Endocrine om S B - S 6 2
P
( Diabcts
Hashimoto thyroiditis (2) *8
862)
Kidhey - 2 Renal
.
changes (2) *3
in diabetes
Papillary carcinoma thyroid (2) *3
4 TypeI and II diabetes mellitus (2) *2
s e

-So

S. Multinodular goitre (2) *2

6 Pathogenesis of type 2 diabetes mellitus (2)
IColloid goitre (2)
&Describe etiopathogenesis of diabetes (4)
B 9 ) 9Grave's disease (2)
0.Insulin dependent and non-insulin dependent diabetes mellitus (2) *2

Breast
A Prognostic indicators and breast carcinoma (2)
Phyllodestumour (2)
3 of breast (2) *4
Fibroadenoma
ASeminone-2
5. Prognostic factor in carcinoma breast (2) *2
b Paget's disease of the breast (2) *2
K Types of breast carcinoma (2)

Bones, joints and soft tissue

Osteosarcoma (2)
Giant cell tumour of bone (2) *2
3. Sequestrum and involucrum (2)
4Ewing sarcoma (2) *3
5 Osteogenic sarcoma (2) *3
6. Chronic osteomyelitis (2) *3
7. Giant cell tumour and osteosarcoma (2)
8. Brown tumour (2)
Male genital system
VBenign prostatic hyperplasia (2) *3
2. Seminoma and teratoma (2)

nrh cli ala, Rcc

 XSeminoma (2) *2
Dysgerminoma (2)

Skin
Basal cell carcinoma (2) *2
CNS
XCSF findings ofviral and tubercular meningitis (2) *3 *4
CSF findings in tuberculous and pyogenic meningitis (2)
CSF changes in meningitis (2)
XPyogenic and viral meningitis (2) *2
Meningioma (2) *5
IGlioma (2)
7. Glioblastoma multiform (2)
8. Bacterial and viral meningitis (2)
9. Etiology of meningitis (2)

Head and neck

1. Mixed parotid tumour (2)
. Pleomorphic adenoma (2)

Skin
Basal cell carcinoma of skin (2)*2
A caide merrtS

Sareial Menigis
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 Printed Pages

PaperID:9521 Roll Number

MBBS 2nd PROFESSIONAL EXAMINATION

THEORY (REGULAR) 2019-21
MBS 201: PATHOLOGY-I

Time : 03 Hours Maximum Marks: 40

Note: 1. All Questions are compulsory.
2 Attempt section A and Section B in separate answer sheets.
3. Marks for each question are indicated.
4. Draw labeled diagrams wherever necessary.

SECTION A
Q1Define Neoplasia. Discuss in detail the laboratory diagnosis of
cancer. (4)
Q.2 Write short notes on the following: (4x2-8)
) Factors affecting wound healing

(i) Obesity
(ii) Cellular ageing

iv) Type 1 Hypersensitivity reactions

Contd......
3 Differentiate between the following: (4x2-8)
) Benign & Malignant tumors
Dystrophic & Metastatic calcification
ii) Leukemoid Reaction & Chronic
Myeloid Leukema
iv) Necrosis &Apoptosis

SECTION-B
Q4 Discuss the morphology and causes of granulomatous
inflammation. (4)
Q.5 Write briefly on the following: (4x2-8)
G) Viral carcinogenesis

(i) Spread of tumors

(ii) Coomb's test

(iv) Paraneoplastic syndromes
Q.6 Discuss in brief about the following:
(4x2-8)
Hodgkin Lymphoma
(ii) Classification of Hemolytic anemia
ii) Bombay blood group
iv) Cytochemical stains in diagnosis of Leukemias

2
 Printed Pages 2

Paper ID: 9521

Roll Number I

MBBS 2nd PROFESSIONAL EXAMINATION

THEORY (REGULAR) 2019-21

MBS 201: PATHOLOGY II

Time:03 Hours Maximum Marks : 40

Note: 1. All Questions are compulsory.

2. Attempt section A and Section B in separate answer sheets.
3. Marks for each question are indicated.
4. Draw labeled diagrams wherever necessary.

SECTIIO A
Q.1 Describe etiopathogesesis of ischemic heart disease. What are the
morphologic changes seen in myocardial infiraction? (4)
Q.2 Write short notes on the following: (4x2-8)
i) Raynaud's phenomenon
i) Etiology of hepato cellular carcinoma
(ii) Pathogenesis of atherosclerosis
iv) Silicosis
Q.3 Diferentiate between the following: (4x2-8)
) Ulcerative colitis and Crohn's disease
arteriolosclerosis
(ii)
(1i) Hyaline and hyperplastic
1 Contd...
 (ii) Duchenne and Becker muscular dystrophy
(iv) Type 1 and Type 2 diabetes mellitus.

Q.4 What are the various possible clinical manifestations of Hepaus

B infection? Describe the serological markers in a case of
acute
(4)
HepatitisB.
Q.5 Write short notes on the following: (4x2-8)
Rapidly progressive Glomerulonephritis.
i) Alcoholic liver disease.
(iii) Germ cell tumor of ovary.

(iv) Enumerate 3 risk factors of Endometrial Carcinoma.

Q.6 Write short notes on following: (4x2-8)

(i) Hydatidiform mole
(ii) Role of Human Papilloma Virus in premalignant and
malignant lesions of the cervix.
(i) Phyllodes tumour
(iv) Prostatic intraepithelial neoplasia
 MBBS 2nd
PRE-PROFESSIONAL
MBBS Batch 2018 EXAMINATION
PATHOLOGY -I
Time :03 Hours
Maximum Marks : 40
Note All
1.
Questions are compulsory.
2. Attempt section A
and Section B in
3. Marks for each separate answer sheets.
4. Draw labelled question are indicated.
diagrams wherever necessary.
SECTION-A
Q.1 Define inflammation. Enumerate signs of inflammation. Describe the vascular changes in
acute inflammation.
4)
Q.2 Write short notes on
(4 x2 3)
() Classify amyloidosis
(i) Chemical Carcinogenesis
(i) Type I hypersensitivity
Giv) Gaucher's disease

Q3 Differentiate between (4 x2 8
) Dystrophic and metastatic calcification
i) Kwashiorkor and Marasmus

(ii) Transudate and Exudate

(iv) Necrosis and apoptosis

PART-B

Q.4 Define and classify hemolytic anemia. Describe laboratory diagnosis of sickle cell anemia. (4)

Q.5 Write short notes on (4 x 2 8)

() Laboratory diagnosis of megaloblastic anemia

i) Laboratory diagnosis of Multiple myeloma

(ii) Laboratory diagnosis of hemophilia

(iv) Laboratory diagnosis of Disseminated Intravascular Coagulation

Q6 Differentiate between (4x2-8)

(i) Intravascular and extravascular hemolysis.
(i) Beta thalassemia minor and major

(i) Lymphoblast and Myeloblast

(iv) Hodgkin and non-Hodgkin lymphoma

 MBBS 2nd
PRE-PROFESSIONAL
MBBS Batch 2018 EXAMINATION
PATHOLOGY - II
Time 03 Hours
Maximum Marks : 40
Note 1. AllQuestions are compulsory.
2. Attempt section A and Section B in separate answer sheets.
3. Marks for each question are indicated.
4. Draw labeled diagrams wherever
necessary.

SECTION-A
Q.1 Describe the pathogenesis of inflammátory bowel disease. Differentiate between ulcerative
colitis and Crohn's disease. (4)
Q,2 Write short notes on: (4x2 8)
()Raynaud phenomenon
i ) Diagnosis of acute myocardial infarction.

(ii) Melanoma
(iv) Acute respiratory distress syndrome

Q.3 Differentiate between: (4x2 8)

) Capillary and cavernous hemangioma

Ci) Gastric and duodenal ulcer of the stomach

(ii) Rheumatoid arthritis and osteoarthritis

iv) Cerebrospinal fluid findings in pyogenic and tubercular meningitis

PART-BB

Q.4 Classify ovarian tumours. Describe teratomas. 4)

Q.5 Write short notes on (4 x2-8)
(i) Pheochromocytoma
(i) Lupus nephritis
i ) Wilm tumour
(iv) Serological markers in Hepatitis C infection.

Q.6 Write short notes on (4x 2 8)

i) Endometrial hyperplasia

(i) Polycystic Ovary disease

(ii) Nodular hyperplasia of prostate

(iv) Metabolic syndrome