Drug Study
Drug Study
Responsibility
Oral meds
Ketoanalogue +EAA      Ketoanalogue +             Prevention and therapy        Hypercalcaemia       Hypercalcaemia,          Assess electrolyte
                       essential amino acids      of damages due to             may develop. In      disturbed amino acid     levels
   Drug Class:         operate by                 faulty or deficient           this case, it is     metabolism. In case of   Assess allergy to
    Nutritional        undergoing a process       protein metabolism in         recommended to       hereditary               the drug
   Supplement          called transamination      chronic renal                 decrease vitamin D   phenylketonuria it has   Caution patient of
                       by taking nitrogen         insufficiency in              intake. If the       to be taken into         the different side
                       from some non-             connection with limited       hypercalcaemia       account that             effects
                       essential amino            protein in food of 40 g       persists, reduce     Ketoanalogues +           Assess vital signs
                       acids. This process        per day (for adults), i.e.,   the dosage of        Essential Amino Acids    Administer with food
                       decreases the              generally in patients         Ketoanalogues +      contains                 to prevent Gl upset
                       formation of urea and      with a glomerular             Essential Amino      phenylalanine. No        Administer drug at
                       prevents the               filtration rate (GFR)         Acids as well as     experience has been      right time, route,
                       accumulation of            below 25 mL/ min.             any source of        made so far with the     and dosage
                       uremic toxins, thus                                      calcium.             application in            Instruct patient to
                       improving kidney                                                              pregnancy and            report immediately if
                       health. Additionally, it                                                      paediatrics.             symptoms of
                       ensures the intake of                                                                                  hypercalcemia
                       essential amino                                                                                        occurs like muscle
                       acids.                                                                                                 weakness,
                                                                                                                              constipation
                                                                                                                              Monitor calcium
                                                                                                                              levels.
     NAH C03           Sodium bicarbonate         Sodium bicarbonate is         Frequent urge to Contraindicated in any       Nurses double-
                       is a systemic              used for the treatment        urinate          situation where salt         check the doctor’s
   Drug Class:         alkalinising agent. It     of metabolic acidosis         Headache         retention            is      orders to make sure
Alkalinizing Agents.   increases blood and        which may occur in            (continuing)     undesirable such as          the right amount
                       urinary pH by              severe renal disease,         Loss of appetite edema, heart disease,        and form of sodium
                     dissociation to         uncontrolled diabetes,      (continuing)          cardiac                  bicarbonate is being
                     provide bicarbonate     circulatory insufficiency   Mood or mental        decompensation and       used. If it's being
                     ions, which             due to shock or severe      changes               primary or secondary     given intravenously,
                     neutralises the         dehydration,                Muscle pain or        aldosteronism.           they'll prepare it
                     hydrogen ion            extracorporeal              twitching                                      carefully, making
                     concentration.          circulation of blood,       Nausea or                                      sure it's diluted
                                             cardiac arrest and          vomiting                                       correctly.
                                             severe primary lactic       Nervousness or                                 After giving the
                                             acidosis. Also is           restlessness                                   medication, watch
                                             indicated in severe         Slow breathing                                 for signs of side
                                             diarrhea which is often     Swelling of feet or                            effects like muscle
                                             accompanied by a            lower legs                                     twitching or
                                             significant loss of         Unpleasant taste                               confusion, which
                                             bicarbonate.                Unusual tiredness                              can happen with an
                                                                         or weakness                                    imbalance in
                                                                                                                        electrolytes or the
                                                                                                                        body becoming too
                                                                                                                        alkaline. They’ll
                                                                                                                        keep checking vital
                                                                                                                        signs to make sure
                                                                                                                        everything stays on
                                                                                                                        track.
     CAC03           Used as a               Used for the                Upset stomach         Calcium carbonate        Check the patient’s
                     supplementary           symptomatic relief of       Vomiting              use is contraindicated   medical history,
   Drug Class:       source of Ca to help    heartburn, acid             Stomach pain          in hypersensitivity,     including kidney
Calcium-containing   prevent or decrease     indigestion, and sour       Belching              renal calculus, high     issues, allergies, or
     Antacids.       the rate of bone loss   stomach                     Constipation          urine calcium levels,    calcium imbalances.
                     in osteoporosis. It                                 Dry mouth             elevated serum           Monitor vital signs
                     also acts as an                                     Increased urination   calcium, low serum       and lab results,
                     antacid by                                          Loss of appetite      phosphate,               particularly calcium
                     neutralising gastric                                Metallic taste        achlorhydria, or         levels.
                     acidity resulting in                                                      suspected digoxin
              increased gastric and                                               toxicity               Ensure the correct
              duodenal pH.                                                                               dose and form.
                                                                                                         Calcium is best
                                                                                                         absorbed with food,
                                                                                                         so follow
                                                                                                         instructions carefully
                                                                                                         and encourage the
                                                                                                         patient to drink
                                                                                                         water with it.
  ISDN         It works by relaxing Isosorbide dinitrate is   Headaches           Allergic to nitrates   Monitor vital signs:
              the blood vessels and used to prevent chest     Feeling      dizzy, Concomitant use of     Check blood
Drug Class:   increasing the supply pain (angina) in patients weak,   tired    or isosorbide with PDE    pressure and heart
   Nitrate Class        of blood and oxygen       with a certain heart       sleepy                 inhibitors such as          rate regularly, as the
                        to the heart while        condition (coronary        Feeling sick           sildenafil and tadalafil    medication may
                        reducing its work         artery disease).           (nausea)               Concomitant use of          lower them.
                        load. When used                                      Flushing of        the isosorbide with             Assess for side
                        regularly on a long-                                 face                   riociguat, a soluble        effects: Watch for
                        term basis, this helps                                                      guanylate cyclase           symptoms like
                        prevent angina                                                              stimulator used for the     dizziness,
                        attacks from                                                                treatment of                headache, or
                        occurring.                                                                  pulmonary arterial          lightheadedness,
                                                                                                    hypertension and            which are common
                                                                                                    chronic                     side effects.
                                                                                                    thromboembolic              Educate the patient:
                                                                                                    pulmonary                   Explain the purpose
                                                                                                    hypertension                of the medication,
                                                                                                    Right         ventricular   how to take it
                                                                                                    infarction                  correctly, and the
                                                                                                    Hypertrophic                importance of not
                                                                                                    cardiomyopathy              stopping abruptly
 (ferrous Sulfate +      -     Ferrous         Treatment of:             GI: Nausea,             *Known                     *Assess for signs of
     Folic Acid)               Sulfate:                                  vomiting,               hypersensitivity to iron   anemia (e.g.,
                      *Provides elemental         -   Combined iron      abdominal cramps,       or folic acid.             fatigue, pallor,
    Drug Class:       iron for hemoglobin             and folate         diarrhea, or                                       shortness of
Iron supplement and   production, oxygen              deficiency         constipation.           *Hemochromatosis or        breath).
       Vitamin        transport, and                  anemia.            Darkened stools         hemosiderosis (iron
                      replenishing iron                                  (due to iron            overload disorders).       *Evaluate dietary
                      stores.                     -   Anemia due to      content).               *Anemias not due to        intake and risk
                                                      pregnancy,                                 iron or folate             factors for
                         -    Folic Acid:             malnutrition, or   Others:                 deficiency (e.g.,          deficiency (e.g.,
                                                      chronic blood                              hemolytic anemia).         pregnancy, chronic
                      *Facilitates red blood          loss.              Rare allergic                                      illness).
                      cell production and                                reactions (rash,        *Untreated pernicious
                      DNA synthesis.           Prevention of:            itching, or             anemia (folic acid can     *Obtain baseline lab
                                                                         swelling).              mask B12 deficiency).      values (hemoglobin,
                      *Prevents folate            -   Anemia in                                                             hematocrit, ferritin,
                      deficiency and                  pregnancy and                                                         serum folate).
supports fetal           lactation.
development during
pregnancy.           -   Neural tube      *Administer with
                         defects during   food to reduce
                         pregnancy.       gastrointestinal
                                          upset but avoid
                                          dairy or antacids, as
                                          they reduce
                                          absorption.
                                          *Recommend taking
                                          with vitamin C (e.g.,
                                          orange juice) to
                                          enhance iron
                                          absorption.
                                          *Provide oral
                                          supplements in
                                          divided doses if side
                                          effects occur.
                                          *Monitor for
                                          therapeutic
                                          response (e.g.,
                                          *increased
                                          hemoglobin and
                                          energy levels).
   Telmisartan        Blocks                   Adjust-a-dose (for all   CNS: dizziness,        * Contraindicated in     * Monitor patient for
                      vasoconstricting and     indications):            pain, fatigue,         patients                 hypotension after
   Drug Class:        aldosterone-secreting                             headache.              hypersensitive to drug   starting drug.
   Angiotensin II     effects of angiotensin   In patients with biliary CV:chest pain,         or its components.       * Monitor potassium
receptor antagonist   II by preventing         obstructive disorders or HTN, peripheral                                 level periodically
                      angiotensin II from      hepatic. insufficiency,  edema, intermittent    * Use cautiously in      during therapy.
                      binding to the           initiate at low doses and                       patients with hypoten-
                      angiotensin I            up titrate slowly.        EENT: pharyngitis,    sion, biliary           * Most of the
                      receptor.                                          sinusitis.            obstruction disorders,  antihypertensive
                                               -HTN                                            or renal and hepatic    effect occurs within
                                               Adults: 40 mg PO once Gl: nausea,               insufficiency and in    2 weeks. Maximal
                                               daily. BP response is     abdominal pain,       those with an           BP reduction is
                                               dose-related over a       diarrhea, dys-        activated RAAS, such    usually reached
                                               range of 20 to 80 mg      pepsia.               as patients who are     after 4 weeks.
                                               once daily.                                     volume- or sodium-      Diuretic may be
                                                                         GU: UTI.              depleted (for exam-     added if BP isn't
                                               CV risk reduction in                            ple, those being        controlled by drug
                                               patients at high risk and Musculoskeletal:      treated with high       alone.
                                               unable to take ACE        back pain, myalgia.   doses of diuretics).    * Alert: In patients
                                               inhibitors Adults age 55                                                whose renal
                                               and older: 80 mg PO       Respiratory:          * Safety and            function may
                                               once daily.               cough, URI.           effectiveness in        depend on the
                                                                                               children haven't been   activity of the RAAS
                                                                        Skin: ulceration.      determined.             (such as those with
                                                                                                                       severe HF), drug
                                                                        Other: flulike         • Overdose S&S:         may cause oliguria
                                                                        symptoms.              Hypotension,            or progressive
                                                                                               dizziness, tachycardia, azotemia and
                                                                                             bradycardia.             (rarely)
                                                                                                                      * Monitor patients
                                                                                                                      with impaired
                                                                                                                      hepatic function or
                                                                                                                      biliary obstruction
                                                                                                                      carefully.
                                                                                                                      * Rhabdomyolysis
                                                                                                                      has been reported
                                                                                                                      rarely.
                                                                                                       *Administer with
                                                                                                       caution in patients
                                                                                                       with liver conditions,
                                                                                                       and ensure that N-
                                                                                                       acetylcysteine is
                                                                                                       used appropriately
                                                                                                       for overdose cases
                                                                                                       rather than in
                                                                                                       general liver
                                                                                                       disease.
                                                                                                       *Monitor
                                                                                                       gastrointestinal
                                                                                                       symptoms and
                                                                                                       advise the patient to
                                                                                                       report any
                                                                                                       discomfort, such as
                                                                                                       nausea or vomiting,
                                                                                                       as it may require
                                                                                                       dosage adjustment.
Parental Medication
Furosemide   *A loop diuretic that   *Used to treat edema      *Common side      *Contraindicated in   *Monitor vital signs
             inhibits sodium and     associated with heart     effects include   patients with         and electrolyte
  Drug Class:       chloride reabsorption   failure, liver cirrhosis,   electrolyte            hypersensitivity to        levels regularly.
 Loop Diuretics     in the kidneys,         and renal disease, as       imbalances,            furosemide or severe       Assess for signs of
                    promoting diuresis.     well as hypertension.       dehydration,           electrolyte depletion.     dehydration.
                                                                        hypotension,           Caution is necessary        Educate patients on
                                                                        dizziness, and         in those with low blood    medication
                                                                        increased              pressure.                  adherence and
                                                                        urination.                                        monitoring for side
                                                                                                                          effects.
Calcium gluconate   Calcium gluconate is    Calcium gluconate is        CNS: anxiety,          •Contraindicated in        • Monitor calcium
                    a medication that       used to prevent or to       tingling sensations,   patients with cancer       levels     frequently.
                    increases calcium       treat calcium               sense of               who have bone              Hy-percalcemia may
                    levels in your body     deficiencies.               oppression or heat     metastases and in          result after large
                                                                        waves with IV use,     those with ventricular     doses in chronic
                                            Calcium gluconate may       syncope with rapid     fibrillation,              renal failure. Report
                                            also be used for            IV use.                hypercalcemia,             abnormalities.
                                            purposes not listed in      CV: bradycardia,       hypophos-phatemia,         • Signs and
                                            this medication guide       arrhythmias,           or renal calculi.          symptoms of severe
                                                                        cardiac arrest with    • Use calcium              hypercal-cemia may
                                                                        rapid IV use,          products with extreme      include stupor,
                                                                        decreased BP,          caution in patients        confusion, delir-ium,
                                                                        vasodilation.          taking cardiac             and coma. Signs
                                                                        Gl: consti-pation,     glycosides and in          and symptoms of
                                                                        irritation, chalky     those with sarcoidosis,    mild hypercalcemia
                                                                        taste, hemorrhage,     renal or cardiac dis-      may include
                                                                        nausea, vomiting,      ease, and electrolyte      anorexia, nausea,
                                                                        thirst, abdominal      disturbances.              and vomiting.
                                                                        pain.                  • Use calcium chloride
                                                                        GU: polyuria, renal    cautiously in patients
                                                                        calculi.               with cor pulmonale,
                                                                                               respiratory acidosis, or
                                                                                               respiratory failure.
Skin: rash
Hydrocortisone    Hydrocortisone is a       Otic solutions are            Headache,             *Contraindicated in      *Advise patients not
                  glucocorticoid that       indicated for infections      nausea, vomiting,     patients                 to stop the
 Drug Class:      reduces inflammation      of the external auditory      diarrhea, increased   hypersensitive to drug   medication without
Corticosteroids   by stopping white         canal caused by               appetite,             or its ingredients, in   prescriber approval.
                  blood cells from          susceptible organisms         indigestion,          those with systemic
                  moving to affected        and with inflammation.        stomach pain          fungal infections, and   *Explain proper drug
                  areas and decreasing      Hydrocortisone tablets        Weight gain, joint    in those receiving       use to patients or
                      capillary leakage.      are indicated for certain   pain, difficulty     immunosuppressive        caregivers.
                      When applied            endocrine, rheumatic,       sleeping, acne,      doses together with
                      topically, it helps     collagen, allergic,         and excessive hair   live-virus vaccines.     *Warn about easy
                      reduce inflammation,    ophthalmic, respiratory,    growth                                        bruising.
                      itching, and redness    hematologic,                                     *Use with caution in
                      while also narrowing    neoplastic, edematous,                           patients with recent     *Encourage
                      blood vessels to        gastrointestinal, and                            MI.                      exercise or physical
                      relieve symptoms.       other conditions.                                                         therapy for long-
                                                                                               *Drugs can cause         term use and
                                                                                               hypercorticism or        discuss vitamin D or
                                                                                               suppression of the       calcium
                                                                                               HPA axis, particularly   supplements with
                                                                                               in younger children or   prescriber.
                                                                                               patients receiving
                                                                                               high-dose therapy.       *Advise avoiding
                                                                                               Withdraw drug slowly.    infections (e.g.,
                                                                                                                        chickenpox,
                                                                                                                        measles) and
                                                                                                                        notifying prescriber
                                                                                                                        if exposed.
Treatment
                                                                                              Administer
                                                                                              bronchodilators
                                                                                              before
                                                                                              corticosteroids if
                                                                                              both are prescribed.
                                                                                              Allow intervals of 5-
                                                                                              10 minutes between
                                                                                              doses, if repeated.
Evaluate for
overuse, which can
lead to diminished
effectiveness.
Teach proper
inhaler or nebulizer
use.
Instruct on
recognizing
symptoms of
overuse (e.g., rapid
heart rate,
palpitations).
Encourage
hydration to reduce
dry mouth and
throat irritation.
Advise avoiding
triggers for asthma
or COPD
exacerbations (e.g.,
allergens, smoke).