Government Degree College Baramulla
SEMESTER 3rd MAJOR/MINOR COURSE
Subject: Clinical Biochemistry
Title: CLINICAL PHYSIOLOGY AND DIAGNOSTICS-II Code: BCB22C301
CREDIT: (4+2) THEORY: 04; PRACTICAL: 02 Contact Hours: 64(T) + 64 (L)
Course Objectives:
• To impart students basic knowledge of hormones,their classification and regulation.
• To familiarize students with different type of hormones.viz
• The students will understand the mechanism of action of hormones.
• To acquaint students with disorders associated with secretion of hormones.
• The students will learn about the role of vitamins in metabolism and the disorders associated with various
vitamin deficiencies.
• The student will be able to identify laboratory investigations associated with diagnosis of hormonal
disorders
• To acquaint students with diagnostic significance and principle of Lab tests used for diagnosis hormonal
disorder or vitamin deficiency
Learning outcomes: On completion of the course, the student should be able to:
• Explain the hormones, their classification, mechanism of action and regulation.
• Know the pathophysiology of disorders associated with hormones
• Explain the classification of vitamins, their metabolic role and dietary requirements
• identify the meaning and use of laboratory investigations associated with disorders associated with
hormone secretion and vitamin deficiency
• Describe the diagnostic significance of Lab tests used for diagnosis hormonal disorder or vitamin deficiency
• Know the principles of analytical measurement of laboratory investigations associated with diagnosis of
hormone disorder or vitamin deficiency
Unit-1: Introduction to Hormones (16 Hours)
General characteristics and classification of hormones, Difference between enzymes and hormones, Mechanism of
hormone Action, Regulation of hormone secretion
Unit-2: Hormones-I (16 Hours)
Physiology and associated disorders of Hypothalamus, Pituitary Gland, Thyroid Gland- Hypo-Hyperthyroidism,
Grave’s disease, Hashimoto hypothyroidism and Goiter, Thyroid function tests, Adrenal gland- Cushing syndrome,
Addison’s disease
Unit-3: Hormones-II (16 Hours)
Physiology and associated disorders of Gonadal hormones and Gastro-intestinal hormones,Pancreatic hormones and
glucose homeostasis, Parathyroid hormones and calcium homeostasis
Unit-4: Vitamins and deficiency disorders (16 Hours)
General Classification of Vitamins, Metabolic role, sources and dietary requirements of Vitamin A,D,E,K,C and B
complex vitamins. Disorders associated with vitamin deficiencies
PRACTICAL (2 Credits: 60 Hours)
1. Determination of Serum amylase activity.
2. Determination of Serum inorganic phosphate.
3. Colorimetric determination of steroid hormones.
4. Estimation of Vitamin D levels in serum
5. Estimation of Calcium levels in serum
6. Estimation of Thyroid hormones-T3, T4, TSH
Recommended Books:
1. Guyton and Hall Textbook of Medical Physiology by John E. Hall, Michael E. Hall. Publisher: Elsevier
Publishers
2. Textbook of Medical Biochemistry by MN Chatterjea and Rana Shinde. Publisher: Jaypee
3. Lippincott Illustrated Reviews Bbiochemistry by Denise R. Ferrier. Publisher: Wolters Kluwer
4. Clinical Chemistry: Techniques, Principles, Correlations by Michael L. Bishop, Edward P. Fody, Larry E.
Schoeff. Publisher: Lippincot Williams & Wilkins
5. Harper’s Illustrated Biochemistry by Robert K Murray. Publisher: Mc Graw Hill Lange Publications
Government Degree College Baramulla
