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SHORT EXAM 3
Blood, WBC, Hemostasis, Immune system
Name:........................ Neptun code:......................
Select the single best answer (1-10)
1./ Which of the following is true?
A. Normal hemoglobin consists of and μ chains
B. Normal hemoglobin consists of two polypeptide chains
C. Normal hemoglobin contains bilirubin
D. Normal hemoglobin contains Fe3+ ions
___ E. Normal hemoglobin consists of 4 units of hem
2./ Iron is stored in RES cells
A. as neutral Fe atom
B. as ferritin-Fe3+ complex
C. as transferrin-Fe3+ complex
D. as hemoglobin-Fe3+ complex
___ E. none of the above
3./ Increased degradation of hemoglobin results in
A. increased number of white blood cells
B. increased hemoglobin concentration in the feces
C. decreased stercobilin concentration in feces
D. decreased indirect bilirubin concentration in the blood
___ E. increased bilirubin conjugation in the liver
4./ What blood type the patient has if his plasma does not contain anti-A haemagglutinins?
A. B, only
B. A, only
C. 0, only
D. AB or A
___ E. 0 or A
5./ Athletes are often treated illegally with erythropoietin before racing
A. to increase energy consumption
B. to produce more muscle cells
C. to increase exercise tolerability
D. to reduce number of stem cells
___ E. to fasten wound healing
6./ Fetal spleen is participated in erythropoiesis
A. from the 6th week
B. from the 10th week
C. from the 20th week
D. from the 35th week
___ E. never participates
7./ HLA antigens are
A. present on all red blood cells
B. present only on subgroups of T cell lymphocytes
C. present on all nucleated cells of the body
D. present on all cell types of the body
___ E. produced only by B cell lymphocytes
8./ Charecteristic to B cell maturation
A. antigen presentation takes place in the thymus
B. cell maturation takes place in the spleen
C. immunocompetent B cells are formed in the bone marrow
D. cells reacting with ‘self’ molecules are selected for antigen presentation
___ E. none of the above.
9./ Old red blood cells are travelling through small pores and sorted out from circulation
A. when they are 2 months old.
B. in fetal liver.
C. in lymph nodes.
D. in the splenic pulp.
___ E. in the bone marrow.
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10./ Measureded erythrocyte parameters are
A. Hb concentration and red blood cell count
B. MCV and Hct
C. Hematocrit and mean red blood cell volume (MCV)
D. Hb concentration and MCHC
___ E. Mean hemoglobin mass/RBC and MCHC
Select the single incorrect answer (11-15)
11./ In humoral immunity
A. plasma cells are formed
B. antibodies recognize antigen epitop
C. the target is virus-infected or tumor cell
D. for antigen presentation, Ag-MHC II complex is present on the cell surface
___ E. memory cells are formed
12./ Typical iron-binding protein
A. ferritin
B. myoglobin
C. transferrin
D. hemoglobin
___ E. albumin
13./ Typical to cells like this:
A. participates in immune response
B. phagocytes
C. lymphoid cells
D. could be smaller than a normal RBC
____E. 20-25 % of WBC-s in peripheral blood
14./ Correct order of activation of coagulation factors
A. XIIa XIa IXa
B. fibrin thrombin XIIIa
C. VIIa Xa thrombin
D. VIIa Xa IIa
___ E. IIa XIIIa fibrin (polymeric )
15./ Cytokins acting on proliferation and differentiation of various WBCs
A. Erythropoietin
B. G-CSF
C. Leukopoietins
D. Interleukins
___ E. GM-CSF
Establish the appropriate association (16-20)
A – direct bilirubin
B – urobilinogen
C – both
D – none
---- 16. binds to albumin in the blood
---- 17. degradation product of hemoglobin
---- 18. synthesized in the guts
---- 19. excreted to the urine
---- 20. water insoluble
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One or more than one of the answers may be correct (21-25). Select
A if 1, 2 and 3 are correct
B if 1 and 3 are correct
C if 2 and 4 are correct
D if only 4 is correct
E if all are correct
21./ Anticoagulants
1. tissue tromboplastin
2. hirudin
3. Stuart-Prower factor
____4. sodium citrate
22./ Basophil granulocytes
1. about 1 % of circulating WBCs
2. are of monocytic origin
3. contain histaimine in their granules
____4. phagocytes
23./ Red blood cell precursors
1. normoblasts
2. reticulocytes
3. proerythroblasts
___ 4. erythroid stem cells
24./ binds to albumin
1. bilirubin
2. gamma globulin
3. antibiotics
___ 4. oxygen
25./ Released by activated thrombocytes
1. serotonin
2. Ca2+
3. vWF
___ 4. heparin
