IMMUNOLOGY-SEROLOGY & BLOOD BANKING
1. He was said to have been given the world’s first b. Anti-U
blood transfusion by his Jewish physician Giacomo c. Anti-N
di San Genesio, who had him drink the blood of d. Anti-M
three 10-year-old boys. 9. Shelf-life of packed red blood cells obtained
a. Pope Innocent VII through open system with ACD anticoagulant:
b. Pope Pius I a. 21 days
c. Pope Gregory III b. 35 days
d. Pope Boniface IV c. 42 days
2. The number of H antigen structures currently d. None of the choices
identified are: 10. Indication for transfusion of neocytes:
a. Two a. Immune thrombocytopenic purpura
b. Four b. Hemolytic transfusion reaction
c. Six c. Thalassemia
d. Eight d. Hydrops fetalis
3. Greatest amount of H antigen: 11. Citrate in ACD functions as:
a. A1 a. Anticoagulant
b. O b. ATP source
c. AB c. RBC membrane stabilizer
d. B d. Caramelization inhibitor
4. Identify the blood type based on the following 12. The most common cause of transfusion-related
reactions: sepsis is:
a. Whole blood
FORWARD REVERSE GROUPING
b. Packed red blood cells
GROUPING
c. Leukocyte concentrates
Anti-A Anti-B A cells B cells
d. Platelets concentrates
0 4+ 3+ 0
13. Major advantage of gel technology:
a. Type O a. Decreased sample volume
b. Type A b. Improved productivity
c. Type B c. Enhanced sensitivity
d. Type AB d. Standardization
5. Bombay phenotype antibodies include: 14. Agglutination reaction: “Several large clumps with
a. Anti-A clear background”
b. Anti-B a. 4+
c. Anti-H b. 3+
d. All of the choices c. 2+
6. What type of blood should be given in an d. 1+
emergency transfusion when there is no time to 15. Which disease might be indicated by antibodies to
type the recipient’s sample? smooth muscle?
a. Rh-negative, whole blood a. Chronic active hepatitis
b. Rh-positive, whole blood b. Primary biliary cirrhosis
c. Rh-negative, pRBCs c. Hashimoto’s thyroiditis
d. Rh-positive, pRBCs d. Myasthenia gravis
7. This blood group is an anthropological marker in 16. The most common fungal infection for AIDS
Asian ancestry: patients is caused by:
a. Diego a. Candida albicans
b. Cartwright b. Cryptococcus neoformans
c. Colton c. Blastomyces dermatitidis
d. Gerbich d. Cryptosporidium parvum
8. The activity of this antibody is enhanced in an 17. This dengue antigen has been detected in the
acidic environment. serum of dengue virus infected patients as early
a. Anti-S
as 1-day post onset of symptoms (DPO), and up to c. Viral load
18 DPO. d. Core antigen
a. NS1 26. Not included as a Hepatitis B serologic marker:
b. C a. HBcAg
c. E b. HBeAg
d. prM c. Anti-HBeAg
18. These are expressed in the developing fetus and d. Anti-HBcAg
in rapidly dividing tissue, such as that associated 27. Autoimmune diseases are mostly associated with
with tumors, but that are absent in normal adult which class of HLA?
tissue: a. Class I
a. Oncogenes b. Class II
b. Sarcoma c. Class III
c. Oncofetal antigens d. Class IV
d. Tumor specific antigen 28. Which of the following activates both T and B
19. Polymerase chain reaction (PCR) is a/an ___ assay. cells?
a. Chemical a. Pokeweed mitogen
b. Molecular b. Lipopolysaccharide
c. Enzymatic c. Concanavalin A
d. Biologic d. Phytohemagglutinin
20. Restriction Fragment Length Polymorphism (RFLP) 29. It is used as the receptor for the sheep red blood
is a/an ___ assay. cells (sRBC) for e-rosette assay:
a. Chemical a. CD2
b. Molecular b. CD4
c. Enzymatic c. CD8
d. Biologic d. CD12
21. Hives and itching are under what type of
hypersensitivity?
a. Type I
b. Type II
c. Type III
d. Type IV
22. Gamma counter uses these substances as labels:
a. Isotopes
b. Fluorochromes
c. Enzymes
d. Immune complexes
23. Treponema pallidum immobilization (TPI) test:
10% treponemes are immobilized. Interpret the
result.
a. Positive
b. Negative
c. Doubtful
d. Indeterminate
24. When reading for a slide agglutination for
Salmonella, macroscopic agglutination is graded
as 25%. Interpret.
a. Non-reactive
b. Negative
c. Positive
d. 1+
25. Other name for “HCV RNA”:
a. Viral clade
b. Surface antigen
