Os PE 7TRAD

Instrument: QUEST IONS

(1). Bone marrow aspiration needle
1
1. ldentify the instrument.
1
2. Name the parts of the instrument
1
3. Name 2 absolute indications of bone marrow examination.
4. Name 1 site (of each) for bone marrow examination on adult &children. 1
1
5. Name 2 local complication of bone marrow examination.

(2). ESR Tube

1
1. ldentify the instrument.
2. What are the methods of ESR estimation? 1
1
3. Name 3 important factors that modifyESR.
1
4. Name 2 causes of high ESR.
1
5. What is the significance of ESR?

(3). Sahlis Hb-Meter

1
1. ldentify the instrument.
2. Name the parts of the instrument. 1

3. Name the methods of Hb estimation. 1

1
4. Which one is best and why?
5. How thalassemia is confirmed? 1

Procedure:
(1). How willyou detect sugar in supplied sample?

(2). How will you detect protein in supplied sample?

(3). An unstained PBF slide is given. Do the leishman's stain.

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 Slide (Systemic)
(1). Chronic cholecystitis
1
" ldentify the histopathological slide.
2
Give identifying points.
2
Complication of gall stone.

(2). Prostate
1
Identify the histopathological slide.
Give identifying points.
2
What are the disease of this organ?

(3). Thyroid
1
ldentify the histopathological slide.
2
Mention microscopic feature.
2
What are the tumors of this organ?

(4). Leiomyoma
1
" Identify the histopathologica l slide.
2
Mention identifying features.
" What are the complication of leiomyoma? 2

(5). Fibroadenoma
a. Identify the slide &write your diagnosis. 2

b. Give 2 points in favor of it. 1

c. What are the tumors of this organ? 2

(6). Tubercular qranuloma

a. Identify the slide &write your diagnosis. 2
b. Give 3points in favor of it. 3

(7). Appendix
a. ldentify the histopathological slide. 2

b. What is the histyologic criterion for the diagnosis of acute appendicitis? 1

c.What is the confirmatory finding of acute appendicitis under microscope? 2

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 Slide (Haematology)
(1). Eosinophilia

a. ldentify the cell focused on the microscope 1

b. Name 4 causes in which condition this type of cell increase? 4

(2). Neutrophilic leukocytosis

a. ldentify the cellfocused on the microscope 1

b. Name 4 causes in which condition this type of cell increase? 4

(3). Microcytic hypochromic anaemia

a. ldentify the slide &Write your diagnosis.
b. Give 3 points of favor of it. 3

Specimen:
(1). Thyroid
" ldentify the specimen. 1

Write identifying points. 2

What are the tumors of this organ? 2

(2). Appendix
1. Identify the specimen with gross/macroscopic description. HH 2
NH
2. Name 2 common causes of appendiceal inflammation/obstruction. 1
3. What is the histyologic criterion for the diagnosis of acute appendicitis? 1
4. What is the confirnmatory finding of acute appendicitis under microscope?
(4). Gall Bladder

Identify the specimen with its identifying points with diagnosis.

What are the different types of gall stone?
What is the most common malignant tumor of gall bladder?
What are the complication of choledocholithiasis?

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(5). Lieomyoma uterus
1,5
1. ldentify the specimen with gross/macroscopic description. 1
2. What are the morphological types of lieomyoma uterus? 1
3. Which type is present in this specimen? 1.5
4. Name 3complications of lieomyoma?

Data:
(1).
1
" What are the lHD'S"
2
What are the non-modifiable causes/factors of IHD;s 2
What are the enzymes on cardiac markers?

(2).
2
" Name the risk factors of cervical carcinoma.
detection of cervical carcinoma? 2
" What are the investigations/screening test for 1
What are the stages of CIN?

(3).
1
a. Define ESR.
4
b. Name 4 causes of high ESR.

Photograph:
(1). LVH
a. ldentify the lesion shown in photograph
b. What is the most common cause of this lesion ?

C. Write any complication of this lesion.

(2). Megaloblastic macrocytic anaemia
a. Name the focused/arrowed cells in blood film.

b.Write down your probable diagnosis

c. Mention 02 causes of it.

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(3). Microcytic hypochromic anaemia
a. Write down red cell morphology.
b. What is probable diagnosis.
C. what are the causes of it?

Problem Based:
weakness, pallor, Mongoloid faces and
(1). Aboy of six years has come to you with generalized
hepatosplenomegaly.

a. What may be the possible diagnosis?

b. What investigations you will suggest?
C. What test will confirm the diagnosis?

worried by seeing that the film shows

(2). During examining a blood slide pathologist become
smear cells, few matured
numerous immature blast cells with high count of WBC some
lymphocytes are seen. Platelet count subnormal. Hb also reduced.
a. What may be the diagnosis?
b. What are the tests to be suggested?

(3). His maternal uncle also suffered from similar problem. What is your diagnosis? What
laboratory tests will you suggest to confirm the diagnosis?
(4). Aschool student of 8 years developed uncontrolled bleeding from the root of the extracted
tooth. Lab investigations show BT normal, CT 20 minutes, Platelet count normal, APTT
prolonged, Prothrombin time- 12 seconds.

a. What may be the possible diagnosis

b. What test to be done for confirmation?
(5). During examining a blood slide pathologist become worried by seeing that the film shows
numerous immature blast cells with high count of WBC some smear cells, few matured
lymphocytes are seen. Platelet count subnormal. Hb also reduced.

a. What may be the diagnosis?

b. What are the tests to be suggested?

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(6). Aboy of six years has come to you with generalized weakness, pallor, Mongoloid faces and
hepatospleenomegaly.
a. What may be the possible diagnosis?
b. What investigations you will suggest?
C. What test will confirm the diagnosis?
(7). An old lady present with soreness of tongue, weakness, peripheral numbness and lemon
yellow tinged skin and pallor. Her blood examination reports shows, Hb- 7.0gm/dl, MCV- 120 fl,
MCH-38 g/dl, Reticulocytes count low, Total WBC &Platelet count mildly reduced with some
oval macrocytes.

a. What may be the diagnosis?

b. What are the tests to be done for confirmation?

8). Afair male of 56 years came with the complain of gradual onset of symmetrical
paraesthesia. Numbness in the finger &toes, progressive weakness &ataxia. O/E, Leman
yellow color of the skin, glossitis &angular stomatitis. His blood picture shows, Hb- 7.5 gm/dl;
RBC- 4.5x10"/L; MCV- 125 fl; WBC- 3.5x10°/L; MCH- 32 pg; Platelet- 110.0x10/L; MCHC- 38.0
g/dl; PBF: RBC- Macrocytic with anisopoikilocytosis; Reticulocyte count- Low. WBC
Marginally reduce with some hyper segmented neutrophils. Platelet marginally reduced.
What is your diagnosis?
What are the other tests to be done for confirmation?

(9). Aschool student of 8 years developed uncontrolled bleeding from the root of the extracted
tooth. The lab investigations showBT normal; CT 20 minutes; Platelets count normal;
APTT- prolonged; Prothrombin time- 12 seconds.

What may be the possible diagnosis?

What test to be done for confirmation?

(10). Achild of 5years presented with sudden attack of high grade intermittent fever with neck
rigidity and purpuric rash throughout the whole body.

What are the provisional diagnosis?

Give the expected CSF findings in this case.

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 11). Aboyof 5 years presented with severe anemia, sore throat, fever and gum bleeding. His
peripheral blood film show gross leukocytosis with presence of immature cells and
thrombocytopenia.
. What isyour probable diagnosis?
" How will you confirm your diagnosis?

peripheral numbness and lemon

(12). An old lady present withsoreness of tongue, weakness,
7.0 gm/dl; MCV- 120fl;
yellow tinged skin pallor. Her blood examination reports shows, Hb-
mildly reduced with some
MCH- 38g/dl; Reticulocytes count low; Total WBC& Platelet count
oval macrocytes.

What may be the diagnosis?

What are the tests to be done for confirmation?

(13). An African-American lady of 30 years, who underwent caesarean section, developed a

raised scar, larger than the original incision. The lesion recurred after surgical excision.

What is your probable diagnosis?

Name three other complications of wound healing.

(14). Arickshaw puller of 45 years presented with weakness, irregular fever and discomfort
after food. His blood picture shows Hb-6.5 g/dl, TC- 30,000/cmm, Pletelet count
80,000/cmm. Most of the WBC(85%) are immature blast cells.
" What may be your diagnosis
What are other test suggest for confirmation of diagnosis?

(15). Arickshaw puller of 45 years presented with weakness, irregular fever and discomfort
after food. His blood picture shows Hb-6.5 g/dl, TC- 30,000/cmm, Pletelet count
80,000/cmm. Most of the WBC (85%)are immature blast cells.

What may be your diagnosis

What are other test suggest for confirmation of diagnosis?

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 His
(16). A7years old boy suddenly developed haemarthrosis while playing and after afall.
maternal uncle also suffered from similar problem. What is your diagnosis? What laboratory
diagnosis?
tests will you suggest to confirm the
from the root of the extract
(17). Aschool student of 8 years developed uncontrolled bleeding
count normal: APTT
both. Lab investigations show BT normal; CT 20minutes; Platelets
prolonged; Prothrombin time- 12 second.

" What may be the possible diagnosis?

" What test to be done for confirmation?
gum bleeding. His
(18). Aboy of 5 years presented with severe anemia, sore throat, fever and
peripheral blood film show gross leukocytosis with presence of immature cells and
thrombocytopenia.
What is your probable diagnosis?
" How will you confirm your diagnosis?

(19). An African-American lady of 30 years,who underwent caesarean section,developed a

raised scar, larger than the original incision. The lesion recurred after surgical excision.
What is your probable diagnosis?
Name three other complications of wound healing.

(20). A4 years boy presented to you with history of skin infection 2 weeks back, oliguria and
high colored urine.

" What is your provisional diagnosis?

Mention it's pathogenesis briefly.
What are the complication of it?

(21). An old lady present with soreness of tongue, weakness, peripheral numbness and lemon
yellow tinged skin and pallor. Her blood examination reports shows, Hb- 7.0 gm/dl; MCV- 120fl;
MCH- 38 g/dl; Reticulocyte count low; Total WBC and Platelet count mildly reduced with some
oval macrocytes.

What may be the diagnosis?

What are the tests to be done for confirmation?
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 symmetrical
(22). Afair male of 56 years came with the complain of gradual onset of
&ataxia. O/E, Leman
paraesthesia. Numbness in the finger &toes, and progressive weakness
blood picture shows, Hb- 7.5
yellow color of the skin, glossitis &angular stomatitis. His
pg; Platelet- 110x10/L; MCHC
gm/dl;RBC- 4.5x10"/L; MCV-125 fl;WBC- 3.5x10°/L; MCH- 32
g/dl; RBC- Macrocytic with anisopoikilocytosis; Reticulocyte count- Low. WBC- Marginally
38
Platelet- Marginallyreduced.
reduce with some hypersegmented neutrophil.
What is your diagnosis?
for confirmation?
What are the other tests to be done
reducing substances.
years old male patient presented with polyurea, urine contains
(23). A45 10.5 mmol/L
fasting blood sugar is 6.5 mmol/L and 2 hours after breakfast is
His
2
a. What is your interpretation? 3
complication of diabetes mellitus.
b. Mention 4 late
on touch.
years presented with an ulcerated growth in cervix which bleeds
(24). Afemale of 55

a. What is your clinical diagnosis?

associated with it.
b. Name the microbial agent
C. How will youconfirm the diagnosis
bleeding peptic ulcer for last 1 year, has
50 years male clinically diagnosed of having a
(25). A
type of anemia you expect on blood
developed pallor. His Hb% is 7 g/dl. What morphological
film? What will be his iron profile?
throat epistaxis and cervical
(26). Aboy of 7 years has presented with fever, sore
with 80% blast cells and
lymphadenopathy. His peripheral blood film reveals leukocytosis
thrombocytopenia.

a. What is your probable diagnosis?

b. How will yow diagnose the case in the laboratory?

(27). A70 years old male presented with severe back pain & Weakness. His PBF reveals
increased roulcaux formation &ESR is 120 mm in 1* hour. X-ray shows multiple punched out
lesion in his vertebral column.

a. What is your most likely diagnosis?

b. How can you confirm it?

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