HEMATOLOGY (SET A)

1-25

1. Which of the following may be used to detect deficiencies in fibrinogen,

prothrombin, and factors V and X?
a. Russel’s Viper Venom Time
b. Prothrombin time
c. Activated partial thromboplastin time
d. All of these

2. Which of the following is describes as an X-linked recessive disorder?

a. Chediak-Higashi syndrome
b. Glanzmann’s thrombasthenia
c. May-Hegglin Anomaly
d. Wiskott-Aldrich syndrome

3. Which of the following is part of the prothrombinase complex

1) Factor Va
2) Platelet factor-3 (PF-3)
3) Calcium
4) Factor IXa
5) Factor Xa

a. 1, 2, 3, and 5
b. 2 and 3
c. 3, 4, and 5
d. 1, 2, 3, 4, and 5

4. A patient’s sample showed the following test results: prolonged PT, prolonged
APTT, and normal Thrombin Time. These result may be found in:
1) Deficiency of Prothrombin Factor
2) Parahemophilia
3) Administration of warfarin
4) Deficiency of Factor X

a. 1, 2, 3
b. 1, 2, 3, 4
c. 1 and 3
d. 3 and 4

5. Statement 1: EDTA causes swelling of platelets (causes approximately 10% increase

in MPV during the first hour)
Statement 2: MPV should be based in EDTA specimen that are between 1 to 4 hours
old.
a. Statement 1 is true; statement 2 is false
 b. Statement 1 is false; statement 2 is true
c. Statement 1 and 2 are both true.
d. Statement 1 and 2 are both false.

6. WBC inclusion bodies believed to be linear projections of primary granules that are
seen in certain cases of acute myelogenous leukemia:
a. Dohle bodies
b. Auer rods
c. Heinz bodies
d. Toxic granulations

7. The patient’s plasma demonstrates prolonged PT results and a prolonged APTT

results. In the laboratory, the Substitution Test was performed and gave the
following results:
 Patient’s plasma mixed with Fresh Plasma: CORRECTED
 Patient’s plasma mixed with Aged Plasma: CORRECTED
 Patient’s plasma mixed with Aged Serum: NOT CORRECTED
 Patient’s plasma mixed with Adsorbed Serum: NOT CORRECTED

Most probably, what is the condition of the patient?

a. Rosenthal syndrome
b. Christmas disease
c. Owren’s disease
d. Prothrombin factor deficiency

8. Which of the following is part of the tenase complex?

1) Factor IXa
2) Platelet factor-4 (PF-4)
3) Calcium
4) Factor Va
5) Factor VIIIa

a. 1, 3, and 5
b. 1, 2, 3, and 5
c. 3, 4, and 5
d. 1, 2, 3, 4, and 5

9. In which of the following cytochemical stains will the cells in the leukemia named
AML, without maturation produce a positive result?
1. Myeloperoxidase stain
2. Sudan Black B stain
3. Naphthol AS-D Chloroacetate

a. 1, 2, and 3
b. 1 and 2
 c. 2 and 3
d. 1 only

10. In which of the following cytochemical stains will the cells in the leukemia named
AML, with maturation produce a positive result?
4. Myeloperoxidase stain
5. Sudan Black B stain
6. Naphthol AS-D Chloroacetate

a. 1, 2, and 3
b. 1 and 2
c. 2 and 3
d. 1 only

11. In which of the following cytochemical stains will the cells in the leukemia named
Acute Promyelocytic Leukemia produce a positive result?
7. Myeloperoxidase stain
8. Sudan Black B stain
9. Naphthol AS-D Chloroacetate

a. 1, 2, and 3
b. 1 and 2
c. 2 and 3
d. 1 only

12. The Philadelphia Chromosome is brought about by the reciprocal translocation

involving the long arms of:
a. Chromosome 11 and 22
b. Chromosome 9 and 22
c. Chromosome 11 and 16
d. Chromosome 9 and 16

13. The coagulation factors that function as cofactors include:

1. Tissue thromboplastin
2. Factor V
3. Factor VIII
4. Fitzgerald factor

a. 1, 2, and 3
b. 1 and 3
c. 2 and 4
d. 1, 2, 3, and 4

14. In which of the following cytochemical stains will the cells in the leukemia named
Acute Myelomonocytic Leukemia produce a positive result?
10. Myeloperoxidase stain
 11. Sudan Black B stain
12. Naphthol AS-D Chloroacetate

a. 1, 2, and 3
b. 1 and 2
c. 2 and 3
d. 1 only

15. Which of the following may demonstrate Auer rods?

1. AML M1
2. AML M2
3. AML M3
4. AML M4
5. AML M5

a. 1, 2, 3, and 4
b. 5 only
c. 1, 3, 5
d. 1, 2, 3

16. All of the statements below are true May-Hegglin Anomaly, except?
a. Giant platelets are expected in this disorder.
b. Patients with May-Hegglin Anomaly show high platelet count.
c. It is described as an autosomal dominant disorder.
d. Granulocytes and monocytes in this disorder show cytoplasmic inclusions that
look like Dohle bodies.

17. The organ that produces the plasminogen is the:

a. Liver
b. Brain
c. Stomach
d. Pancreas

18. All of the statements below are true for Glanzmann’s thrombasthenia, except:
a. Abnormal clot retraction
b. Normal bleeding time result
c. Abnormal aggregation response in adrenaline.
d. Abnormal aggregation response in collagen.

19. Which of the following stains is helpful in the diagnosis of suspected

erythroleukemia?
a. Peroxidase
b. Nonspecific esterase
c. PAS
d. Acid phosphatase
20. Which of the following choices exhibit partial albinism?
a. Hermansky-Pudlak syndrome
b. TAR syndrome
c. Wiskott-Aldrich syndrome
d. Chediak-Higashi syndrome

21. Faggot cells are most frequently encountered in:

a. Acute promyelocytic leukemia
b. Acute myelomonocytic leukemia
c. Chronic myelogenous leukemia
d. Acute erythroleukemia

22. The patient’s plasma demonstrates normal PT result and a prolonged APTT result.
In the laboratory, the Substitution test was performed and gave the following
results:
 Patient’s plasma mixed with Fresh Plasma: CORRECTED
 Patient’s plasma mixed with Aged Plasma: CORRECTED
 Patient’s plasma mixed with Aged Serum: CORRECTED
 Patient’s plasma mixed with Adsorbed Serum: CORRECTED

Most probably, what is the condition of the patient?

a. Hemophilia A
b. Owren’s disease
c. Factor VII deficiency
d. Either factor XI deficiency or factor XII deficiency

23. Concerning Chronic Myelogenous Leukemia (CML) and Leukemoid Reaction (LR),
which statement is true?
Statement 1: Both are characterized to have markedly elevated platelet count.
Statement 2: Both are characterized to have increased LAP score.

a. Statement 1
b. Statement 2
c. Statements 1 and 2 are both true.
d. Statements 1 and 2 are both false.

24. Which of the following is improperly matched?

a. AML M3: Acute promyelocytic leukemia
b. AML M5: Acute monocytic leukemia
c. AML M4: Acute myelomonocytic leukemia
d. AML M7: Acute erythroleukemia

25. Which of the following is improperly matched?

a. AML M7: Acute megakaryocytic leukemia
b. AML M3: Acute promyelocytic leukemia
c. AML M5: Acute myelomonocytic leukemia
d. AML M1: Acute myelogenous leukemia, without maturation