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Drug Study

The document provides detailed information on two medications: Omeprazole and Metoclopramide, including their classifications, mechanisms of action, indications, contraindications, side effects, and nursing responsibilities. Omeprazole is used to treat gastroesophageal reflux disease (GERD) by inhibiting gastric acid secretion, while Metoclopramide treats diabetic gastroparesis and gastroesophageal reflux by promoting gastric emptying. Both medications have specific dosing guidelines and require monitoring for potential side effects and contraindications.
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0% found this document useful (0 votes)
28 views4 pages

Drug Study

The document provides detailed information on two medications: Omeprazole and Metoclopramide, including their classifications, mechanisms of action, indications, contraindications, side effects, and nursing responsibilities. Omeprazole is used to treat gastroesophageal reflux disease (GERD) by inhibiting gastric acid secretion, while Metoclopramide treats diabetic gastroparesis and gastroesophageal reflux by promoting gastric emptying. Both medications have specific dosing guidelines and require monitoring for potential side effects and contraindications.
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PDF, TXT or read online on Scribd
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Jannah Michaela Paus October 12, 2024

BSN 3 – 5 D
DRUG NAME CLASSIFICATION MECHANISM OF INDICATION CONTRAINDICATION SIDE EFFECTS NURSING
ACTION RESPONSIBILITIES
Brand Name Pharmacologic Interferes with To treat  Cold  Give
Prilosec Class: gastric acid symptomatic Concurrent therapy symptoms omeprazole
Losec Proton pump secretion by gastroesophageal with rilpivirine-  Fever before meals,
Zegerid inhibitor inhibiting the reflux disease containing products; preferably in
 Stomach
the morning for
hydrogen (GERD) hypersensitivity to pain, gas once-daily
Generic Name: Therapeutic potassium  Adults and omeprazole,  Nausea, dosing. If
Omeprazole Class: adenosine adolescents substituted vomiting, needed, also
Antiulcer triphosphatase (H+ 16 years and benzimidazoles, or diarrhea give an antacid,
Route: Gastro- K+ -ATPase) over. 20 mg their components  Headache as prescribed.
Oral Oesophageal enzyme system, or daily for 4  Hypertension  Know that
Reflux Disease proton pump, in wk.  Back pain because drug
gastric parietal  Children age can interfere
 vitamin B12
cells. 1 to 16 years with absorption
deficiency of vitamin B12 ,
of age (long-term monitor patient
weighing 20 use) for macrocytic
kg (44 lb) or anemia.
more. 20 mg  Encourage
once daily patient to avoid
for up to 4 alcohol, aspirin
wk. products,
ibuprofen, and
40mg once daily foods that may
via IV Infusion over increase gastric
20-30minutes or secretions
slow IV Inj over during therapy.
2.5mins  Monitor
patient’s urine
output because
Route:
omeprazole
Oral may cause
Intravenous acute
interstitial
nephritis.
Jannah Michaela Paus October 12, 2024
BSN 3 – 5 D
DRUG NAME CLASSIFICATION MECHANISM OF INDICATION CONTRAINDICATION SIDE EFFECTS NURSING
ACTION RESPONSIBILITIES
Brand Name Pharmacologic Antagonizes the To treat diabetic Catecholamine-  Hives  Know that orally
Metozolv ODT Class: inhibitory effect of gastroparesis releasing  Difficult disintegrating
Reglan Dopamine-2 dopamine on GI  Adults paragangliomas, breathing tablets are not
receptor smooth muscle. experiencing epilepsy, history of recommended
 Swelling on
mild for use in
Generic Name: antagonist This causes gastric dystonic reaction or face, lips,
symptoms. 10 children
Metoclopramide contraction, which tardive dyskinesia to tongue or
mg 30 min because of
Therapeutic promotes gastric before meals
metoclopramide, throat increased risk of
Route: Class: emptying and and at hypersensitivity to  Agitation tardive
Oral Antiemetic peristalsis, thus bedtime four metoclopramide or its  Anxiety dyskinesia and
Upper GI reducing times daily for components,  Extrapyramidal other
Stimulant gastroesophageal 2 to 8 wk. pheochromocytoma, reactions extrapyramidal
reflux. Maximum: 40 when stimulation of  Seizures
symptoms.
Metoclopramide mg daily in gastrointestinal  Be aware that
divided doses.  Rash metoclopramide
also blocks motility might be
 Adults  Depression therapy should
dopaminergic dangerous such as in
experiencing  Lack of energy not be used in
receptors in the the presence of
chemoreceptor severe gastrointestinal  Sleep Problems patients with
symptoms. 10 depression
trigger zone, hemorrhage, because of
mg 30 min
preventing nausea before meals mechanical increased risk of
and vomiting. and at obstruction, or suicidal
bedtime. I.V. perforation ideation.
injection  Monitor blood
given slowly pressure
over 1 to 2 throughout
min for up to therapy
10 days  Assess patient
before being for signs of
switched to intestinal
oral obstruction,
formulation such as
and abnormal bowel
continued for sounds,
diarrhea,
another 2 to 8 nausea, and
wk. vomiting, before
To treat administering
gastroesophageal metoclopramide.
reflux disease  Urge patient to
 Adults. avoid alcohol
Continuous and CNS
dosing: 10 to depressants
15 mg 30 min while taking
before meals metoclopramide.
and at  Warn patient’s
bedtime for 4 family or
to 12 wk. caregiver to
Intermittent monitor patient
dosing: 20 mg for abnormal
as a single behavior or
dose prior to thoughts that
provoking may be
situation. suggestive of
Maximum: 60 suicidal
mg daily in ideation.
divided doses.  Stress
IV INJECTION importance of
- Adults and reporting signs
adolescents over age and symptoms
14. 10 mg undiluted that are
given slowly over 1 to persistent,
2 min. severe, or
- Children ages 6 to unusual.
14 years. 2.5 to 5 mg
undiluted given
slowly over 1 to 2
min.
- Children under 6
years. 0.1 mg/kg
undiluted given
slowly over 1 to 2
min
Route:
Oral
Intravenous

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