AIC KIJABE COLLEGE OF HEALTH SCISNECES
KRCHN (BASIC) MARCH 2015
END OF BLOCK 1
PHARMACOLOGY EXAMINATION-
DATE:TUESDAY 17th 2015
TIME ALLOWED: 3 HOURS 9 AM TO 11.30 PM
INSTRUCTIONS TO CANDIDATES:
1. Read the questions carefully and answer only what is asked.
2. ENTER YOUR EXAMINATION NUMBER AND QUESTION NUMBER on
each sheet of paper used for your answers.
3. All questions are compulsory.
4. For PART I (MCQs): Write your answers in the spaces provided on the answer
sheet. Each MCQ is 1 mark.
5. Omission of or wrong numbering of examination papers, questions or parts of
the question will result in 10% deduction of marks scored from the relevant
part.
6. No mobile phones are allowed in the examination room.
7. Each candidate MUST sign the examination return form after handing in ALL
the scripts
8. No candidate shall leave the examination room unless accompanied by an
authorized invigilator/supervisor.
PART ONE: MCQ
1. Nevirapine is an example of anti-retroviral drug in the class of:
a) Protease inhibitor
b) Nucleoside reverse transcriptase inhibitor
c) NNRTI
d) Fusion inhibitor
2. Possible first line treatment with High active antiretroviral therapy ( HAART) is:
a) Two NRTIs and Two NNRTIs
b) Two NRTIs and One NNRTIs
c) Two NRTIs and One PIs
d) Two NTRIs and Two PIs
3. The mode of action of Nucleoside Reverse transcriptase Inhibitors (NRTIs) is
a) Inhibit viral reverse transcriptase and viral DNA synthesis
b) Inhibit viral protease –preventing maturation and replication
c) Blocks viral fusion and inhibit viral transcriptase
d) Blocks the DNA chains incorporated into Viral DNA
4. Administration of large doses affect the pupil
a) Atropine
b) Hexamethonium
c) Pilocarpine
d) Carbachol
5. Action of Atropine during administration of inhalant anesthetics is to reduce
a) Muscle tone
b) Secretions
c) Nausea and vomiting
d) Diarrhoea
6. Indicated for asthmatic attack
a) Ventolin
b) Lobeline
c) Homatropine
d) Atropine
7. The correct dose of ibrufen for pain control is:
a) 500mg orally
b) 600mg orally
c) 400mg orally
d) 800mg orally
8. Main nursing consideration during administration of Digoxin is:
a) Check for any previous episode of allergy
b) Take apical pulse for 60 seconds
c) Measure the blood pressure baseline
d) Measure electrolyte especially potassium.
8. Drug of choice in the emergency management of
anaphylactic shock
a) Methoxamine
b) Terbutaline
c) Norepinephrine
d) Epinephrine
9. Hypnotic drugs should:
a) Reduce anxiety and exert a calming effect
b) Induce absence of sensation
c) Produce drowsiness, encourage the onset and maintenance of sleep
d) Prevent mood swings in patients with bipolar affective disorders
10. An example of hypnotic benzodiazepine drug:
a) Zolpidem
b) Valium
c) Secobarbital
d) Phenobarbitone
11. The correct dose of Acetylsalicylic acid is
a) 300-400mg orally
b) 500-600mg orally
c) 150-300mg orally
d) 100-200mg orally
12. An example of analgesic, without anti-inflammatory effect:
a) Diclofenac
b) Paracetamol
c) Metamizole
d) Aspirin
13. Aspirin is used for Prophylactic purpose in:
a) Non-cardiogenic pulmonary edema
b) Peptic ulcers
c) Thromboembolism
d) Metabolic acidosis
14. Appropriate choice in the treatment of most anxiety states is:
a. Barbiturates
b. Benzodiazepines
c. Lithium salts
d. Phenothiazines
15. An example of xanthine bronchodilator drug:
a) Atropine
b) Orciprenaline
c) Adrenaline
d) Theophylline
16. An example of proton pump inhibitors:
a) Pirenzepine
b) Ranitidine
c) Omeprazole
d) Trimethaphan
17. The correct dose of H2-receptor antagonist ranitidine:
a) 50mg OD
b) 100mg OD
c) 150 mg OD
d) 200mg OD
18. A drug that may cause reversible gynecomastia:
a) Omeprazole
b) Pirenzepine
c) Cimetidine
d) Sucralfate
19. An example of prostaglandin E1:
a) Misoprostole
b) Warfarin
c) Frusemide
d) Omeprazole
20. A drug used for pernicious anemia:
a) Ferrous lactate
b) Cyanocobalamin
c) Iron dextran
d) Ferrous gluconate
21. An adverse effect of oral iron therapy is:
a) Anemia
b) Thrombocytopenia
c) Headache
d) Constipation
22. An example of low-molecular weight heparin:
a) Dicumarin
b) Enoxaparin
c) Phenprocoumin
d) Heparin
23. The correct dose of Warfarin is:
a) 2.5-7.5mg
b) 5-10mg
c) 7.5-10mg
d) 10-15mg
24. An example of anti-anginal calcium channel
blocker agent:
a) Nitroglycerin
b) Dipyridamole
c) Minoxidil
d) Nifedipine
25. The dose of Captopril is:
a) 12.5- 50mg BD
b) 50-100mg BD
c) 75-100mg BD
d) 100-150mg BB
26. An example of a diuretic agent for hypertension treatment:
a) Losartan
b) Hydrochlorothiazide
c) Captopril
d) Prazosin
30. Tick the diuretic agent – aldosterone antagonist:
a) Furosemide
b) Spironolactone
c) Dichlothiazide
d) Captopril
31. Currently used second-generation sulfonylureas include the following,
EXCEPT:
a) Glyburide (Glibenclamide)
b) Glipizide (Glydiazinamide)
c) Glimepiride (Amaril)
d) Tolbutamide (Orinase)
32. Aspirin should not be given to children or adolescents with viral diseases
specially in varicella and influenza because of its association with
a) Reye’s syndromeCopyright@ www.nursingplanet.com/Quiz
b) Rett’s Syndrme
c) Anphylactic reaction
d) Hepatotoxicity
33. Aspirin, NSAIDs, and acetaminophen can act by:
a) inhibiting the synthesis of prostaglandins.
b) increasing the production of prostaglandins.
c) activating the cyclooxygenase enzymes.
d) releasing histaine from the mast cells and basophils.
34. All are side effects of phenytoin, except:
a) Ataxia
b) Hypoglycemia
c) Hirsuitism
d) Gum hypertrophy
35. Specific adverse effect of Biguanides diabetic drug metformin (Glucophage)
therapy is
a) Hypoglycemia
b) GI distress
c) Lactic acidosis
d) Somulence
Short Notes
1. Write short note on Digoxin using the following headings
I. Classification
II. Indication
III. Dose
IV. Two side effects
V. Two Nursing Consideration ( 5mks)
