OCR A Level Biology A – Topic 3: Biological Molecules
1. Monomers and Polymers
Monomers: Small, basic molecular units (e.g., monosaccharides, amino acids,
nucleotides).
Polymers: Large, complex molecules composed of long chains of monomers joined
together.
Polymerization: The process of joining monomers to form a polymer through
condensation reactions, which release water molecules.
Hydrolysis: The breakdown of polymers into monomers by the addition of water.
2. Carbohydrates
Monosaccharides: Simple sugars like glucose, fructose, and galactose.
o Glucose: Exists in two isomers—α-glucose and β-glucose.
Disaccharides: Formed by condensation reactions between two monosaccharides.
o Examples:
Maltose = glucose + glucose
Sucrose = glucose + fructose
Lactose = glucose + galactose
Polysaccharides: Large carbohydrates formed from monosaccharides.
o Starch: Energy storage in plants; composed of amylose (unbranched) and
amylopectin (branched).
o Glycogen: Energy storage in animals; highly branched structure.
o Cellulose: Structural component in plant cell walls; composed of β-glucose
units forming straight chains linked by hydrogen bonds.
3. Lipids
Triglycerides: Composed of one glycerol molecule and three fatty acids; formed via
condensation reactions creating ester bonds.
o Saturated fatty acids: No double bonds between carbon atoms.
o Unsaturated fatty acids: One or more double bonds; can be monounsaturated
or polyunsaturated.
Phospholipids: Similar to triglycerides but one fatty acid is replaced by a phosphate
group; essential components of cell membranes.
Cholesterol: A lipid molecule that helps maintain fluidity and stability of cell
membranes.
4. Proteins
Amino Acids: Building blocks of proteins; contain an amino group (-NH₂), a
carboxyl group (-COOH), and a variable R group.
Peptide Bonds: Formed between amino acids through condensation reactions.
Protein Structure:
o Primary: Sequence of amino acids.
o Secondary: Folding into α-helices and β-pleated sheets via hydrogen bonding.
o Tertiary: 3D structure formed by interactions between R groups (e.g., ionic
bonds, disulfide bridges).
o Quaternary: Complexes of multiple polypeptide chains.
Functions: Enzymes, hormones, antibodies, structural components.
5. Water
Properties:
o Polarity: Uneven distribution of charge allows hydrogen bonding.
o Cohesion: Attraction between water molecules; important for transport in
plants.
o High Specific Heat Capacity: Buffers temperature changes.
o Solvent: Dissolves ionic and polar substances.
o Density: Ice is less dense than liquid water; insulates aquatic habitats.
6. Inorganic Ions
Roles:
o Hydrogen ions (H⁺): Determine pH.
o Iron ions (Fe²⁺): Component of hemoglobin.
o Sodium ions (Na⁺): Involved in nerve impulse transmission.
o Phosphate ions (PO₄³⁻): Component of DNA and ATP.