Topic-wise Classification of Questions
Unit I: General Pharmacology
Introduction to Pharmacology
Q1(b): Define drug, pharmacokinetics, and pharmacodynamics.
Q1(g): What is meant by drug antagonism?
Q1(e): Define efficacy, affinity, and therapeutic index.
Q2(a): Explain in detail various routes of administration with their advantages and disadvantages.
Q1(a): Write in detail sources and active ingredients of drugs.
Q2(b) [Alt]: What are the sources of drugs, give examples.
Pharmacokinetics
Q3(a): Write a note on transport of drug across plasma membrane.
Q3(j): Explain pharmacokinetic terms Bioavailability and Half-life in detail.
Q3(f): Define drug distribution, write factors affecting it and add a note on volume of distribution.
Q3(h): Explain factors affecting drug absorption.
Q1(a): Explain enzyme induction and enzyme inhibition with example.
Q1(g): Define absorption, bioavailability, and bioequivalence?
Unit II: General Pharmacology
Pharmacodynamics
Q3(c): Explain G-protein coupled receptor with example.
Q3(e): Explain the JAK-STAT binding receptor transduction mechanism.
Q2(c): Define & classify drug interaction. Explain pharmacokinetic & pharmacodynamic interaction.
Q2(b) [Alt]: Same as above.
Adverse Drug Reactions
Q1(d): Explain drug addiction with suitable example.
Q3(f): Write a note on adverse drug reactions.
Q1(c) [Alt]: Define tachyphylaxis and give two examples.
Q1(f) [Alt]: Define anaphylactic shock with example.
Drug Interactions
Q2(c): Define & classify drug interaction. Explain pharmacokinetic & pharmacodynamic drug
interaction with example.
Drug Discovery and Pharmacovigilance
Q1(f): Explain the importance of pharmacovigilance.
Q1(d) [Alt]: Write a short note on Pharmacovigilance.
Q3(g): Write about the clinical evaluation of new drugs.
Q3(d): Discuss phases of clinical trials.
Q3(c) [Alt]: Write about the process of development of new drug.
Unit III: Peripheral Nervous System
Q1(c): Enlist the difference between sympathomimetic & parasympathomimetic agents.
Q2(a) [Alt]: Classify sympatholytics. Write MOA, adverse effects, and uses of propranolol.
Q2(b): Define & classify adrenergic drugs with examples, explain pharmacological details of
adrenaline.
Q3(i): Pharmacotherapy of Myasthenia gravis.
Unit IV: CNS (General)
Q3(d): Define general anaesthetics & explain pre-anaesthetic medication.
Q2(d) [Alt]: Define and classify sedatives and hypnotics. Write effects and uses.
Unit V: CNS (Specific Drug Classes)
Q2(d): Classify opioid analgesics & write pharmacological details of morphine.
Q3(j): Define & classify antiepileptic drugs. Write MOA and therapeutic uses of phenytoin.
Q3(h): Define & classify antidepressants and add a note on MAO inhibitors.
Q3(e): Discuss anxiety and add note on anxiolytics.
Q3(i) [Alt]: Enlist neurotransmitters of CNS and explain neurohumoral transmission.