ee es) ee ee
Te
The nevvyous System
- For vapia reyponse
-AcnON petennals # Neu vO TaN gmitter
- Convolecd
- con scvoustyCerth cercliorwm\ °F
—-6 Wi Cand cient y (Vlas emManc OVaANTIMaANe
ret{lexes
The Endocune System
Bteae Re Coser huntorce protom jeaicee esau
ugey NEmmencs Trance elt cd in ME HIECd
*ConWotled via Feedbact 1ooPy
Nervous System quence) @ [ee]
BEGIN: eRe CTIA S NTE
-SPUNO! COVE * Zi AAVANGA ENTERITIS
Brain STructurty
voor ec brum , Dienecpnoten, Craingicm +
cere BEUIM
ifwe ¢4t THE Cerernrum corenally
- Gareiicumca mig
7 2-Umm of gity Matter
“FolOus contouls OF gyn F Suter
stncreagcy amount of gicy mottter
for agen aren
7 CONGcious Thosiont + yecogmuman of
Gtimate COT ERM
CONSC(CY3 Con TOL am sey
cerebral e + RommGenesronSyvatey
oe cy -ecep toy
receptor | = genvory | abberent neuron
Graingiem, T Tre CNS for Wtegrahon
\ tl “ Spina’ covai sensory tract)
ohm NE Tran! through brain gicm
spinel yO ceve bran Corer
Tang erovd auencepu Ue eee eee ae eo
Seen
The nevyous System
- For rapid rou pense
-aAcrion petential/ € myocu FO Trangmitters
- Controlled
= con Sci Ously¥ Crit Cerclrum) OF
She Gia Cana Guns (yla coma heiovFantismeans
vetlexe7
The Enaeccrine System
prarongeda reseonuc
TANGP OCT CA in Me lescd
* For Clover, MOVe
=ugey necnones
*ConWotled via Feed bac’ lors
Neweous System Qvemmiess etwas
~ BALA: QDS IRNSINREINISTINTERN IES
- Spine! cord Sipe Spee eV ITER
Brain Structures
-Cerctrrum, Pirnecenaian , werainGcicm
Col Siete
2p ice Cu EC cere pihums conen oly
— GEMM S SNS
-2-Umm of grey Motter
“Felons contouts OF gyn toute
siAcreagcy amount of gicy mottrr
POtNOARIGE NER, BASE
-CONGC1OU) Thoygnt £ rccognitras of
GTimatle PED ORE
CONMSCICV) Con Ol nae
(Rommensovgivatss
vepral A
TST tex fh ee
ficce Ree — Sensory | aFerenr Heuron
eu: = te CNS for wteqcanon
PAN : tt | “Spina\ covcli sensory tract)
a SA Ur oa ec
eee yO Ceve pra Cortex
CONGCLOVIS Quecinc asFee motor contre!
~Cevetoral covtsx
Spe Os ECU Ds I OMe
- Bmpuls cu Mavel AP Gviehn icles
mMresgn Cereomim # Te braiaatem
- Spine cord
» Mote Wack? Cacscenai hr)
= Synaece witha moro’ GueneD eaten
= Wwhien leaves Mme EMS via oe Mote: (etferent
news
—Etfeete! organ . musciC
Congciesy Con red
+ Beeps Gen vot Bervovs guste
CONSCIOUS COMM OL -AWOVy SOMEHSSMPUCATeEA
Mor! PAM CV Nd AHNWOU Duy petTO 28 iy eveagingy
Compt cated acner)
fc eQ running
~ Hewerey fer Thy te occur
TRecvuc Imeutyes muwt TWoavel Furmer.
Taso ugn Many More Sy nsp des Geennccnsos)
-~MOKS SYyNapscy Gleurgs The reacNeaA NM
Reflex
+ (AVERTED VEST ROHS TOTS AMG
eal)
— ReRPEEesy CA inimat Synarscs
7 (RGOMCICIEMR: Sam rod PONYE Every ume
= Yymmeenit | connote ee improvect Oy reps He
ASTY SPOON FY Soon ErthebmnbamMoay ov retiec
are
PRP PPPrAPARPrRA PARP eRe eee OU Oeees
Reflex Aron
- A mma OCC ASTIN
| OGM COM CAECT? OTN OF)
petent ats Mmrougs me nevve # AoWal
voot to Me Gpinal corr
-In me Gpinat com, We genyel DJ neuron
Syoerpcey with an ETE CNC ATCO | (TEETER NOD,
amam (ANINtcrenror 1G net 'nvowed 19 a
mone synaere veficx arcn)
The (neciheuron cynearey ith 4 Gi
DEMO
tothe moter neuren axon COncktcn %
caren
ecotenthalts TMmrougn Mme ventvat root * spine!
VEKNC 1c an GRREETSMEONSIN- ”
Ret{lex ty
- By pave me consciow part of Me wren
+ can occur Wimert Wigner efein Center
wvolvemen* |
"Mintime! numer of SYynapsey [conn cen y
Re{texey can be Classi fico funcrenally a
either: GSomane or Autonomic Cviscerar )
S$emenc rettexey
+ ACA with CmSiRTAIERRD m1 AS CIE J
—remove the Cody (rom pain(ul eTmut?!
= Keeping balance /powtur<
= Invowes cither the gRinal cord or RYAN hy
—atlows for qurtce vas poouc
au the integranan Centre
AUtonomic Rete,
einvotvcy contyol of |
~ SHRIBION AMIENS CH Atl OF biCOd vVesse\eu etc)
— GEUMSMAIOMNAWUEe Cm NCavt) |
= BISARYIMSEEE Cyt Gan, sauvary grandee tf)
ae re r |
poo eee eee eee d be
bdHAVA lS Hantarning pwoaily fuNcMmeny,
Eq HR, BP, Kloss CO2w levels
- movement OF Food ANYONGN Aigeahyc
Saqgtem
TAefccan™ # mectan non vefrey
TMWIOKk On dame periNceln ay Omer reCiece,
eT GCampn@ekye GeELNel Corch
ee Teg mictuni ON, eegecaNOn ve fleyn
— Bratesrem throwgh anricnomre ps
monet cue BP crc
Bray notem
e COMPpOC“UcA CF three party
ie Sc a
7 Bos
*pumienvyt part of brawn
slay many impertand integrana centr
(ESMaISrNRTENERIESISEIMNEH Fawy cL OTC ct NEM VON
= ALCENAING MH Aes Cemia! 9) Wwacty Fave!
centre
Trough thi region
‘Has important @ISIe) fo' SHALSIINGINGEGONGT <
Te Cay =
*ReEe{lEx es arecay inciuade, ty
— Waissniceumnietnrersy .
scoordmatcy heat 4 cys Moements
“Tract moving Seycciy
~ Paanminimenmpelielnlaesed me
-grelytve ve (ie
Thc piencephnaton al
stniee pay ty mace Up mc wetty of me Sut
venwect< aie
RIMS | ScHUOKY ftlay GRAN O519e
> Gmuinliaamaudais' "og. taton of emeotiony +
Civcamran TAYMmM® Ja
+ ARPPSMOMEMBG - mM PorteAt VA many HOMess tate
mecnanrsem >
* SeutsmacwawWAGE involved (nN cod NOIlIag motor
fancnen?
ae‘The WIpoTHata mw
_ CT = =
finvertca mrangie ANoPrt
*Aeex pointy
TaAMtTiony * aovnvara
KH towaraty the piirtary glanct
» CenNnech aM te Mme er ranray @ Lan ct
— QRS vo intundibalem Cp tuto
Stave)
~ Gee, (0). vst > NETVOUY
areact?
simperiant mM many homeostams mecnanisna ,
Se eel
-cegulancon of GiepmvancuetmeeGis
~regule to Of (eemumemeusr
HVegulanco of SCHneNamsearcusccenAmmanicemy
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svegntlanng eee
capganay
CC QULSTC > —pieRUNS me NZINON Mm GEEKEINS 7
ating. ectuitary crlong
“Small pea Vi2et Qiank
TAWIACAINIO 2 peta (CACh GIENIEIa pe
Sep CHaTLey, )
= Premarin OOTG an ctenohypponye'y )
“grow Gom 10Sf of pout
tis mac< Of Gilteumceromeete,
- CBEREMON CN curshy popnysis )
racen groom fem wrain
> Thei ce Or 14 GISRUENEERISE Ege
PRARPPRPPrRER PAAR ARRRRRRARRRPateror Brita
5 Maaec Evrom 2ST.
- ecenppemsM cn of the pees CTOENGISR|a)
SS COV ETE) NOE MOR CD (0 | STATIS )
V from
ermonc , aWeKEhoy
7 re veaniagiin nie eng
MIA ReneS Oa eo hicapitlawitenncetise
are
SEES ci + ATEN SSE
ee ‘
~ rlermenes of tre ACT Y é
am GHEEANMEE MON < Co) ~ target ASun-
target
ite ws
ee Ces) =
qawgets MNT
a \aitaleasioaiaaianseremniSTOMRIET (LA) tare c 1 wewonics
teatrcenerminerC
= QRONGERMD = Tar@t SmemNCUEEEMVM 6.4
QUanid-
Farge CRAM (mcranocyt cu)
YX poer'< nocmone -Sccretcoat fromonce gtann
< CM SH)
PO) ETE OA Te: AUN OMREY) COME OMNirese MMMM CA
Beeb bee BP ou oa na en a oo oo ah i th
i
EBegtctror Prtuiiary
tae fron PERG SUGaaie
tSemeiey porn on Of es tuitard C20°80 Ny
~ GEOWNASTNPMSI Bieta Soimiaag CINOTTCPIDES SES RUE )
- 2AM ASSO Aivcetly «9a pilayma
Travel ay fret Norwmone,
- pegrackc« rapicty
eee ee* Cilagsmet estes tema wre AT CRU OP UISLE)
TIMMS +t commen, os 1 SPEC OURO 7
ele OK. Got
—eceu me AeemenemGonitingd 69 Slesct
\ ecictnstey
ee
—proceceu D Of
* rtacncs wren enter The blicca
vweSSCt € Kolgare NETMEHE fn THe Nive
where Ntcaca
tle: mene Ken cn
+ (eerie IRENE UU STN CACHEETSTKESEIPSTS / Sp) Cr atom
Tacmemmeyger ceuws ( MUNEHove~amacepirs: (>
have an eteect )
+The rece pliSr-can be citer
— (aemendictrcmmaremeenwide (ME 69 cyToplaym
or nvcteus )
-Hermene Must o¢ agsWeFOTalftus c
TRNELON Mc prewpPNOu—l himenreran<
Only \PWAMESUGBWE TIN CKM ona Can
aD Ms
ruses AKeeO Meme ct acna
Cia 6 Oitmrere c+
cen:
onty SME Gomiere) Normoncy
ust Thi MemMmod
RBneE Phot pr Cewimemvvan <«
PMY St wc an _umancersimcmoct
ef acnam-
PRPPRPRPwPRPRARHRARARARRRARP RR FEbbe bb bh bbb bed oo oa oo oo
* +ROMIRIOIRIEL Can
v
CHEN Ca ee eTOCs aay nal PESIoaS/)
riopaoemey
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‘increasing oF ae crc easing WrOAKtener
Hoo fs atuiacm ehMe a?
wr Gaemeermiaumomennenmiotanescotsouty’ sy St
Me normenc
~ Bepmcmyounib <<
- citer coCcan Ger mroygn
ceu memerant -
toy | Mg
- SEMA (Cert CoSTEN OVD, ASR ASLO,
prOCgeaterenc )
hinp Ad Wa Triioasmy' N9CR)
Tetra; aothronine CUS
VRID LNT SOCIO C
> PENSE {can't get Mreughn
ceu_ memerant )
+ ucRNeIETM MOSES! (Seconda mee engacr
Cmsot common)
: SME CACTH tr, TOM, ADH
Nypethatamic velcagine, factor 4
giveag en eTtH). Ditece Messenger Mechanism
1 Kmomnnmanicecemmacsh Can StriCSBemETMe 19 1h
mien bian
SWC CUOSHEAOMANOMIC >
* Stiemmaremicmnian ia Gns —
- CorncostTcroca,, T2, Ty
Feats atcrone, PLegeUTTTENt, OCU WOQTH
epi SOE RATAN EFTel So !
Mytopiasm or nucterts )
+ Bom AStman 6 + receptor comp Cox Then
passes SHU eteas CMrougn otCticar
envereee )
_@enVates opeciftre genes
= pas of BNA roller RNA,
= CyROPIEU Mn TOT YH ESGOMm ¢
- opnermonganeitcy
- effets erOtTI Nn GYOMC.
IRarrect method ot hotmen= acnen-
sccona Messenger mecnanismy
“Meemens Mat cannot cuttove thHreugh
Mmemibrcn ¢
Tic Weter Gow (not iora goturtotc )
~ NR boora (net Talty) 4 Protmr CactH
LH, FISH, ABH, ny pOinaLtam'c rete aving
norment / factor’, Giucagen , e TH)
sMtoemenc Cis the first meseenge) meutuTae
SEM
+ Ceu receptor ON Mt GuTdllae of a cell Membranr
7h < pISIIRSIRTSWENTRGA Seis PITOT
~ AEN AKON NANG proreib compicx
Thich in turn aller Fete votc cr cme
forman'on pt Semon ng oninneninog
Aoadkeny! -eyctase Can enzyme)
PRRARRRARRRARRHRRRA RAR
Rfht bh hh bE HEEB E OU eae eae eh ee
ey
a Raven CHOLATe conv cmbcu ATP SBS CAME
Ceyews ame)
pacntvaty protein = Cimasey C regatonw
Tc
enzyme >)
oy cc RM SAO TS NMANESSS Ages
-— Gwranging cel Pcimea biuty
- athvatng Omer enzymes (Eins) ’
— inereaving, pretein 890 treuiy
7 oT mutanng ecera non
— efpcetmuwce con Wane 4 rclaxca Wor
- GAMP Ceetnch CE GIAAEA + me effects otCe
to connne< effect need mere nemeonc,
entwvot of tHormone reicas S
_"- ameenias
~ ScovetzTal in airect Pespome te chang (ng
Biecd (every eg par th yroiaCa?*)
7 Neuvyal Sfmt
—hemty Coen cnrrcctly GMmMutait
tess eommon
=1e€ aadrena McAuUlhanG9YM perre M Ci
—1n reyponse 19 NOmmoned by OtHer
eEnaocine Crugany ¥
Te9g TOH SMmutaty Thyrorot Qranar
Neganye Feeabace (ors
PHOrmonc Gecve non Affectca bY Chang'ag
\evety of car arlanhng hormone (svemance
tn me blood.
fe concentranon OF Yinaeases his fcedboces
YO) Gland B ENicn in tein Locrcaycy The
CECICO®M Of tloimonc K UNnicy re tuces The
eve of ¥
ont)SA SING eve | aty¥ Prigges M<
VeSPonsc to vreauce vevelu of Y
Gaisaygrc)
=
freee ans a
RK __attercen processe
That
atkcet tm conceANORSD
of MinIRmSCeSe
“cf pancrcose
TAY ghecosue levers
WO THE Blcce Ke the
ces
pannvtasye SCCYEIT
loses gincorc
Allowing wpocdy
uptarce of
(nme
LODGED. Hagin
CASES
Levels te occiune bY
cCeww a
QurecOoe
LocrcauTe their
i een
|
ams refinery
(ECHR y
ee eer
tn blood
2 YERCLCAG EL CLP ARDEA*thatecetig using a releasing linn binng
factor
5 Hypornatames
i ew
tlormone|x retcasing/
— RAEN [OST LO
{REREIENIB CC pituitary
x
thommon ey x
v
Alter cell process ©
that afrectmimemacememon
YVirminmiateerey
SH ypotrctiamy >
TRIES Wenn eA MS alii
nermepnc
v
= Puuitary
meeeIneEcy. Gana
a
\__ Binigproncts @% pone
* QNSMIEEey- pont
> premminmg © arouna
ok€icral system GAS
- ipl: creatc , form
- “Nelo: bi caw Aown
> em cet
~cengrto Te tleGiw Companies he sonraqure rewosucton op
—— Aadal Skeleton ‘Appendicul keleton
Posterior view
Axial Skeletonconnecnw¢ Tssuc
. : ry organ 19 Tre
boay, congists Of eetiUmecpemcnticaminens
CACMTOTREr by an AbUneant exTracetluta,y
nerves ©
Bones carniagt, tendon) 4 Ligament an
Conmnecttye Tissues =
_ Conncetnseuegurorone aQMome:
__ SHIPPOTTSVTAG POWAY of Me COAd .
protcanian
So tepneMeSHWBEGAEB (calium , Phe cpOate, rigiyere-
rides)
“mincrar nem oG tagiuy
Car lag
7 OMEKCREMMOF CREME (non celular Guogiance
CONSISTING Of NEA fibrous proteins 4 omer
DAMME Sach au proved py cons) + aC
RMON CC Ct YeCnOMmonrOWLAdi, Which Onno
“Metaboliicaity CACANO GA CMPAMG CEH
"10 ANMOUSEENGS SO Ce\\lor needs Must
al{fuse to cewW
“Nov CACROCNeUNpCagiat
PERWOTSRAMHaM —+# Thee Cells PORN.
PU OPP PRPRRRRRARRHREAALLLACarniage Greot .
_S bepawemeumqnesim (cach (age aAmeearemn ¢
oe qwmremmiages Of the existing carniagt
dome x bet—
ween Mme chonarocgttY
re eo, of cart lage
-Hyatine: co
= Cokwonqrermprmws¥ cs are S ietumHIeWeny” aiGpevesec
y In THE matriX,macing the Manx aepca”™
J TVA RUPORERT ) Te CRISPI «
CoerGmoqgnsa, oA att founicmwAweaces
Olacanac wun The frm but flexible
mes
er a
PROTRACTED) vi Th CORcmm prin Anta)
mmcwemac: , BROREA. , 1 SUN s8OUNG)
rO, Thovt I
COWAGEN™™ FOL ES SMCs
2 _yNyOUinieReCaPNMmaN g < The fiery asx apmeme
2 uEROSUEMACIRRANOMAC cerrivergeund
0A CACC ELANTRA
- pomewhat Peciet« + capable of Withotancing
qmenNORImamemens: , CSMOCC ITe eOS »
“Seng C CHE CAMO MG NTA VEGA €
RN CREGNENERIET., SigpaMSIORIMKIENS, SOMES 9 //~
Loca ho ge ae
Bub EE U Ree eee oo
>
j_Biagtvie earn tage
6
Similan te hyaune carniag’ but
matrix saiwou contain s etease cf OZ
- Browickeumniclitty with even moctifiex(bituny,
—___ Trvcunmatn ip calaitiataine ATL UGE 12 CANS CTEMERI TY €
Fo Abw rerure me mer ovnginet whape
C=
attier beng treet nea
externa cars, cpigioto, ava tem Mec
Bene cells
- owwrebiagty :
7 bene forming c4ew produce Mme Chemicals
# STRactUncs that mate Up The manmix
> OM Ginate in ancapevioarenm
PP maintain theo Mamex
= LO CeHtEI NIN Speci alivcad gtrecturcy
COM EA yrcanae
= bone ae gtvoying CE’ wereacc@oun
ThE matrix
i bawge multi nucitatcad Cells Ori gmat ¢
in red oone marrow
~SPecia\sed for tcapuorpnman. mopisec
CoH.
Bone Matis
a
= COUAQER fiercy, protcogiycan 4
- carbon, Hay oregtay Pip ni negen
> pPretein Or
joecass aemety by CUITebIa0+
+ maintains wy cde OC ayTT
- ES ROT Gane
- Hyaroxyaponts Ga Pouce rata)
ROA MAHRARARARARRARARRA RS
Jt.
Tnb ib hb bh bn bh be nnn bab ob an wo oe oo
7 CAaIciuUM tony + pneophate tony
Cmineral_ part)
TMade from avso1ecdA snorganid (calaum
+ Phospnaic tan) bY ouvitobliactl t 7
How accu pone matrix foun?
+ OSTEO BIAGIYS
- formation of pone Through cssificaha
or Oogtecgeneo!
—__—_ctemaeaieioaitntnidaactonseecciemMaBIR A GG —_
Releauca by exocytosis
— PiCeurger of hy aroxapante STOrEA 1a
VEONENE men veleaccA by eKocytoGis
clypty of bone growm
+ VSHONWICI
~Fetal aeveiopment , initic reparr oF
fracture
= Cea gen fore vandemly arrange
7 woven bone i6 Broten Aeon by
Aieowactasts 4 reformea (ato thin
Sheets cated lamella
= cowagen Fiore, AtC parale\ yo each
omer in eacn lamevate purin atthe t+
lameWa the covagen fibres nave
CuftrevenrtwoutembermOny.
+ WOWNg) UPper + Lower Iymbs
° GIIOMIN' cay pat 4 taney
BWM ries, Stemum, 6 KAN Ucapul
> weveigMWar veicorae, face)
Megoadcim tf Mesenchymal Mosue
- Gham gionre™ preeuirsem cell 4 feoue Otbane.a eerie
STapeMe
— areimracalyoes COCT) wesocesmbe' OS =
— appre! pore contains caumns
bone cated trapecuta€ Generally
EPC RIEC IO RSE +
gouveundea ey & =
ESSE ~ MOPMSSEMMIS « Found 10 spine
> era AY SONS ppecdiis C1oy
end af tong Cone -
+ Commupiceet
T POUR CON BON UAC APES ( AVONO?
me outvidt)
= Baste unit ts Th. < CAISARSMNCNMNRTeINeNeEe
System
Compact bone crrcuan ZO>
apriforanng Canals anor ical vessel
from perooteum ro eEcnemate he
cOomact wenc-
; syeusels Cf Me central canal
7 -Natvieni? 4 Gaotes mavel re 4 from
Fi orteocyity via
= =intergmmal fluta of lacunae # comatcul
i From outeocytos to MIeogyNt by GOV"
Bi junocnon >
- Flat, Short long 4 Wecgular bone?
4 - Se
a =O Alaphygss epipnyse Gananearcn
- ot GPONGY between compact Kone
4 - seme flat tivregulay bones Of te
SKUW nave Sinuses IONE A by Mucous
Mem orants
phot 4 lyre gular:
~ COMPact pone That sUrroundy weone
bone Cenve See Qe
&
=
=
=
=
=
=
&ech cpipnyse
of long benaw NO elvapmysiy 4
hot elongatca
+ womigibon c |
= Shaft ,largity compact bene
— Cem © entangGgomeniInlofameoone,
Cargiy spergy eon’
se Joetween aAtaphyd! J
4 epiphyseal, alse Enovn av THe
grouth pirate itis matte of nyaline
carnmlage present anti tgvosth
strep
— EpiIpHYscamlMaAk vocation ay For
tprpnysest plate Cartilage is
replaceqg PY leone + The bone 6 tops
growing iniengith
— MISCUNAKY MCA: to coiaren, contain)
reaAmarror, gradully Meo Changes
ompeyicie ie aliapinierorniee 4 Te SCuN.
Rest Ch gCeieren Contains red marrow
SS
=
at KAKO affecnag wonc OX O36! 99
shutinan, hermencs excercive # gene nc
—= - BAClomot en benty
: Tack of catcium protean t O™Mcy
= nunients aureng grout A
a AevclopMent can cavit Boney 10 be
er Smetter.
= +P
a - negEcssa'y For collagen syn cuts
by CStEelHladts:
“= } vaniqa
san cKecess Can have -ve effect cone
peatthas:
=tnowl be meaty several bone Mati
proteins putitity inconciugive !&
neal tA
Suppiimenranen EMprore bon oO
: ey
—~May affect bone heal
+ calc OSA
7 proauced in myrera grand.
TInv Owed IA Cazt+ NOMEOGTASII tolcauent
WAH vevels are 00 NON, Aecrcaucs
eyteociast acnwity.
7 ant Prd
> snMetates cntperngaNat qavatage
growm™ A appesOGl bone growth
CalaumM nomeestaris
‘bleed jcatcuum necay be eo CoeNmatant
level Aepends en carasm movement
‘WwoUur of lone
shee a FO aecrraye caterum in blood ! Osteo Blasty
hew bon«
* Nee te incycave Cataum: ote OCleuts Kreac
CQO
+ PETE) s me ey regulater of bicoa catcium |
levels. Reteaseatancn eorex levers
bow 4 aivectiy otimulata ourcociacts
tO ‘eure AK AOWN pone
Cale. TOnIN vElcasca Whee evely are nigh —
Acaveansey osteonact acivity |
Wi YA calaym neeacad ?
steicasc of naswrotrangmistes in newve Wand -
MiESslorn
PmMuUscle CON TWacna
-Diocad clothny, enZymc atacter(Pi D toi Do oD no Ho oa Hh @ th oth th wo
Mechnomcet smess + Boos remo dang |
* FlOmGes (KC jRRIPLAQ, wen? ect arc
CANCA mecnancal Gregor
mecnanical Stes! cavoty bone remoaenng
Yan inccade OM bone WFARREIT massCaens ty)
wot) ohew-
AVaning of rabwccylat
Fomange causca ey osteo plaut acmurty
WHC En erceues with GUEIION [Odea .
Bones ¢ Jain
s AiviGiony Of GeEete hon
= GM | (GIOMEBB Cs >
Alewemcuiculeys( (26)
Besos Bing Bone
+ bileenel — eniargca enc
2 Boe main part of bone
1 WIEN 7 CONGTICRON beTACEN Head 4+ BoAay
7 Miewgicuguiisenmac’ - cA QT
+ CODEN - Smooth rounded avy nculay curface
MARLLLL LD
+ Awvayoyne — bend
: Remon ~ brancn off body of eon?
< BaleeT—- ermat! flattenct arnqguiaycurlacc
eroycenons
— PYOCESR - PVOMMm ant prajyce han
7 Wembemene - smoatt round oumyp
T_MupiremO«swiye \CNO|O
- Tweenraimicy — Atoevrogi mer on prone
femur
— Epreomag! ~ncay jacove a condyleClassi pcanons of Joint)
tbaicA on me mayer connectvt Msguc
+ Flo rouse
— Unite by Albrous CT, nove Neyeont
Gavuty, move a lotrle of net arall
—_ Guonep ecm): Spice oviae seh GOO
pegs mat fitinne socket pewocdental
Vigameati' hola teem 19 place
—___ amy | ofpposinguipons) ene? _
InicraAigitare with eer'ostcum of
the omer, Guitural WgQament two
penosica pluy Aaenve, fbiouy,cT
between in aaults mre yout may
OSSAY complettry
~ SUREEAUIGM pOhes arc furme a pact
Than in a suit 4 are jyorncet by
ligamenl. gome movement may 4 cour,
+ CANT ag enous! es
7 VNtitterworooncs by mecang at
CArONVAgT, (4 Tt OF NO MHeVement,
may be permenant or rcplacea
by cthcr Kyecs Of jyornts
— eras) S Oe Ort Fempody + eine
Keplacea by Gynenonadrosty, same
LE Coo Fecnonaral pants AwEeloP
Syeovial jJarnw
ae |
=
ce
LAA AAA
AA
Signy moveawir.
SmMovveN
oy cootainy synovial Flu vo, allows
considera e Movemenb camel Jain
— moot are jounts thor Marte pone" OF
GPPEN AI Calar Geereron, 1ePlecr
a Ot ap PEenarcnitarsi
a
eR ct movement
2 A jon ae Gtructure Keterm Mes the
Ty Pc mor) eceumm there
MS
7OOMC Joints only nave enseturpe ot
Movement, others can move in severol
\
Aw cohens
“OROMEIVEARSE can ve Glowsehweomas
ew bee ee ee eee eee eee=n cele roo
Vana, fees ron,
{| GWMMSMION Support, GrOrage, ASSIST 10
MAOKEIMENT, prOTCENE , DIOOANCEM COA OY
* RcuoemcoInopeNcaNy ct TH dEEICtal Cystem |
oc
“mittanougm tt) carverem nemrcoctauiy:
7 Gaver tenga C Tyres A Qtand) s encoragey
COLTS BIA tS to AcpoutT CalauMin wene
Creauce prose catawm )
—eTH Cpaothyrad grand) sindirectly
‘Nr cauty GUtTO CAST active ty CiNercauc
biecd calcium )
Desc pmons of pens, 4 party
. Teorrnamcton ° targ@t proyecnm
1 PVP 21 WHMCS YOUN ACA Pi Qyecnon
7 BSW Shallow aeprcesgion
* Gomororen + opening C scur Sea Re
1 (EGH : prommnant rage
+ eReeeGs preycun
+ CRM OWA. Oe WAY
+ FESR Bove oUN Sit.Funcnens of the mugarlas stem
“ONSHEMERTE Of Hx body
“MaAnNtamence of PSCC
* Cerna
Genera - wscte)
U prepeiticy o € muase
+ conibraertimty: abuvty OF mudscte fC Sherten
WIM force TO proarce tensien
_1 Bxltitadombintyy capaciiy of muscic to red pond
tO a Stimulus (from nerveu or nor monce )
# must be capable of transmitting acnon
petennal-
+ SK TSH CUEING | Muscice can oc _stretenca
to \t norman Yesning \engte 4 beyona
ROmw mAs Cheam AG Once
< CUATTEITYD alvity Of mMuccte TO Veco +
original reghng lengm aficr gtretcne Or,
ZLyepes of muscie 1 SSUE
+ Quareuinanizanin:
~HOT of pedy weight
7 Feyponsibie tor: locamonon,
tegpiration, posture, masncatrr
facial expieccion
“ generally atvache@ 10 bone (facal
muses nor attacncd
—_ CONN Sniroyze See eR
Cprpyysetrem ) extend |
PACPCMEL which in some casey iv
lengin of whole MusdCic
~ mulMpic nuclei, penphtratty (ocatcat
CAPRA ORR OO OO ROO OObbb b bebe eee ede oe 2 oe oe oe oe oo
shas srvianens
- no gpecial ce artacoment?
~ Voluntary (involuntary (1eflacu)
connol
“hot capabic cf spontaneus contrachon
-Found in natiow organs 4 Tube cg
brencniote, gur, biood vessels
= Cell Chapc: spuNmEamainapEn (KS=2ooKmmA
length SEgpmeavanmetcr
TIM Ole, central’ y lOcaica nucieus
- CEN Cel attaMment: @epmpanemen J
porne~owie WweeramEmMoeFh Mmugcie”
Gems rogtincr.
a (nveluntary contro |
- capabic Of Jpontraneus Contraction
Tonty foundinneart+
Sato nee
- Cell Snape: Gyetinemnucamamranchice
oe" O pm cena 2-20 Aremete J
SINGie, CentyanY locatca hy ceus
=intercalatca aroce join cttly Magemcr
~hav gmanon
“involuntary Cntrol
~Capabie of Gpon tanews con fracnenben c
> TANS FEIN The [OC HOnEANGANOY one
Ghorten avatar of He M4gd¢ Thro ugh
Tenden men to bone)
= €eimysium surrounds Rete made <
TF REImMYSsi4M: Surroends GqeWErey |
AWGUERMISKEU. Cacn aroup cailcea
frorsver Tendon >
Strectucst ef a Ker stal muscte f fileve
“Sacielémma plasma memvoranc
= SAeNEplasm | (gto pIoum es
7 Mat PlGrqueber at pen pnery
(O48 of mitocon arin
“Myonmomey . Cglin ari cal OVrganetls within
SAWOpiaumM.
. SARC OPMOASENCNV ET TCOMUND (imo OT! Ee)
TSTOVAGTe OfCa?*
7 terminal cigttrna are CNIAVACA Sacro—
Plasmic reticulum iocatcd eithev ciac
of T-tubulc
2 _ TROT GNENammmTTBIS NN) invaginations ef
SAacroleMmMa with win Aeecpr int the cei
AuEUS SEUS SI a eRe
- Sith myofrerls theca
\
\
— Se a bb anol)
+ BRENISTED im TH MANN SMPaeRINsTE NT
Uletauoeetmbament & racKATyoRllanicnay
Through | ami
z are bana)
* EREATIAMIC f —_ CACCNAAMNPTNEASSE TIT
- A Bone egnoMemaEAEBeGGEN her <
AISTINEEOMNT AOMASNTOVE TIC -
+ MANN | (in Tc RANMA amalen men
pornmaton mice MYO Ramen Ns
1 Sacvomerc OES MAREN R AN TIAA IRONS
Ol myefitaments—
= FOC) ZameANSICRROMZNTONS 6
— GIES isnnizammanm for Ske cto! Muscle
Mint
[pT 7. = actin Cthin )
j d ¢ Myos M(tMice)
Myofilameny.
HHH tf ff Of OO ee
Tband fA bana
U HU RMyosin (thc Frlamen
large clongatca protan made
many myoula motccutcy , 1ock€ UK
—gelf crubs :
“Myosin neadsy can pena at wage "ego
QUOWS binaing te active siity on me :
actA Moiccul <> fo form cvoss= ori ACS
* Myoutn heads ace “cock ca” uphi gant.
ready for acnon wien AIP atacney TO
The hingt weenon 4 breten Gown 1nid
AvDicteResteacmrenay
TSit at 4b “degict g towards Their
Tared (fowaras the Mine)
“Tne oreatdown of NTP tiperaice energy
cocking Mm my outa Neads Up 10 A0 Acq
“Nien myourl noaays are upri get. me winding
SiIt on Mmyourn (aces upwaray.
“When Catn of MC heads Swivels, rey
SWIKE! DaCkK [TO CViginal HS Aeg towaray
TAIN position (towards Miine)
Acnn/( thin) Myofilaments
Conta +
oF
Tact 4 aompecnemxmpretienn wi.
ach epyTRaINgG site
+ GENAECKIOMETNREY 10.9 ¢thcr +O feiMh
th
vh oth th
bpHnno nh hana i i ht ft th th th
.
VW ft iv
~ Woponunucnangweeace te (ty erigine\
Shapt
TWrhalicn movyty treeomycutn back TO
Gevee the lelinioniinig”eetc on achnn
eStia ing. Eitamecon* mode)
+ MYyofitamenungivole pas T CACN Ofer
7 thin Filamenty are arrangtNiower Mick
Tomaras M-Net
s NO Lengm énange tA actrinoY myouIn
t Muse con trornen~ ghertening of (OO Ss Gawomercs,
Muscte contiecnon >?
each Musa (6 Servet py meter nerves
— SIEQUEHIEN : SORA ES HEWN cs
~ SHASSNA: aaTOMOMiCHEVEL | AISMRS <1
—_cdemoukoe | MERORSMICTENS cs | WERRIOOS/
7 CAM mere! Merve Contains Many Nexto
70 eatr newe entem Me muscie it OvaRCne? A
TYOS Through The cOnncctive Mesue layers
Neurons Tetminatc ot Memuscre cell ata pone
cated the neuremuccuiae jyncnon
~ PRORYRAPTOAC WING | IM o«
A metOl newton cAI,~SYyRapMemededst | gE cctcen me &
T pes synartc membrane [mete” ena
Piate: 0% hc SeiesowemmM +
EX citation -contitacnon Coupiny
i MeChanniam Where BY a cnonmpoTen aly
SO Me Scarcolemma (cad te myouiA F
acnn 'oteracn eo
* As com Rachi¢ prove my intctact. Sacvomers
Shorten The Whole MUSCLE, MHS Gtarty Fe
butia ap fenscon by palling em the beoy
attacnments of me muscles via tencden J
1 ESHRCTAEROTEN Os gmecthorsthan the Weck)
misetonic conceatiwnonCmevemtnity
oecurdy
AARAAAR HA
—Semetriic (poe mov
TPAStOrat Musccy OF me boay.
Winichn LATA VONE YOM MT emven a ciamot a
“Thi 5 1emCATEHIO® { s Lonmboteet byl an achin
potenna! From a motor neuron
FMusctéey are Mache Of many Muscte ceily
hea feg ether PY Conncetive TEsue Whicn
hold it arrect the force towaras me end
of Me MUSCIC TOme tenaen « onte bone
LoMrenaamion Of Gpeciiauwidicctmconmnacniemproncin
=
Extenuer : extend seme thing
t * SUPIMaTOr > Supinate forearm
CVA AZ IM
TAMALETON Qa auct domething
7 hevaror! ratue geome Shing
"moot wet weea omer quentier
for former seccih# canon
7 MINEO » Frame ©
2 longs, oreviy
7M orimey | meacsy, MiAIMMS
rR eP
‘ie
Y
ain
ay
| of fn hit
wii
T ft
rnd:=F Furncnons of me neart
3 —gencranng pleoen "predsurt
: Vemutbuneimmonena :scpc (Ott puimonary a
69S FeMIe Chycutanhons
_ ee vatwr 4
Negulanng Bleoa GUppIY to mMatéh Changing
Mmetawowe neeaus
te Soxygenetey pleect
: RODR BO Sts dysrem is
—_ FRISRIGREFF Rear t
7 be prcusdre = 16 reg atance
= Neart > organs (not lungs) 2 heart
~ beng (ese
Thy gh pressure = nigh resistance
~ Provlats vexy gen: tea plecd te body
Locaneo
a
=
=
start (ecatca (9 MmeatiesTin am
meatostinum aiviades Moracc Cau ty inte
Mett + egntr part
+ Wacnca, cevepragas, my mus, bloed vesutiy #
NOWNE) AWS 1a mecoosTO4M, Lungs cimer utac
EENELINg zlayers
= Fibrous pericavaium for ammemonage 7
=a}
a
=~ SSTUOATS I |
~Xtpicaravum Cviseral pee’'cacaium)) smeo'
Cuter layer of neat
~ mye caraum (caratac muscles
mbes, covery
ware? chaocaraium(tiones CNA
valvey) mugcic coo Wacriens.
Coronary Ciiculanon
L =
=
E
E
E
> bloca supply th mi Myocaratum itsclf
Svignr al Chteovonavg artcrisy ave He frst
branches of the aucenaing aorta.
slLarge atcits travel io oute: on heart ou) face
SmMatier brancnty penctware the myocardium
* bLCCA retuUIny via CcAaralac veins WwinsCn Aran
vate me coronary vea~e Sinus ON the Podterior
surface of Me neat t hen HK gNnT atvium:
BLcoA Ficw
é systemee y
o> pulmonary
qt
>
; Ps
RARAAHReReAaAAR RRR OP OR GR
al1m ow ob ow om
Heart valves 4 areecnon al wicod flo
2 At OVCRWicUlar vaive”:
~between atria «ven aicies
— left varve = ic apea= mitral valve
~ vignt vate = tricusp a
1 MEMURG Hac Vass:
7 between veamces + great valve)
Sregnt ventricle A pulmenary MUN
Thett ventricic * aorta
Ev orow geere ton ot ncart
‘1 Gee RRCSSAAaS) SMES! The
4 wowwe
ioumianty
- anchorage
~ ConnCKECeCEE OMNES) Sel
7 eee Weal Pagatarien petween ara
tvenmicicy
Cara acmusl ht
PRFED! sMlatcd, prancned, intereatatca Atecs,
aemeaseme, gay juncnon:
(as pwergeumimmcemmns < lisimicitealieia ciiielorumuer ata
Cosmelel 2 eeu Ri atoning vevy Four electrs coil
| ae-actim
+ Caravac reuewt is Me Afference BETWEEN CO
A perssn can acnicve - AT recut * max CO
— WEAN GN ERERENEIEUEIMC | Thc _AmeCTEMT €
CAPCREGIISR Un A ci TAIN C) UEKORNOMEEMETORD
io
=o
_ factors aftecn ng heart rate
= SA 4 AVNCAe Ennervatca by parasygmpatenc
4 6ympamene Hore
_Senmetied mrougm caralovascrlay Centre
la _ medutia eolengartn
* paKasyrnpamenionnenwes (via vagus )
= innervate OR 7 AV nodes
T tran smi rter - ace tyicnoinc
7 _GOComtTie
7 Alminant ah rcut
+ aymiplememicnnerweyl(via Meraaa gpinatcoraS
—_ {FR hec ater GumIISACe <
> t¥angm i tte: Thema acenauae
-inerraye HQ
- aadrenaring
= nonadrcnaliae
= MYyrerh Nermane)*oMmer
~ boay remp
> Arugs
— Steep
— Sress peacerc
Factors ficcang Snoce velume
Tanyming mar aflect) AR will awe aftcct
CO wut Gv docutnt cnangye
* Pretota, conttacnuty ¢ after toad aticct SV
Paso a oh
+ thc 'Ferce’ of (LOBAL ON Me yen THiCUlar My Ssere
just prion te coanntacttan
* Aetcrminea by cad awrouc voiwme Cebev)
“draringy baw of Who heart |
= Rne Gerater Me filing ct meheare
e— eos halt uAS)
“Le aumepunmgomaleee WV
| \qouevuwonsumay COMO 1 Of UV
“\enocuummenunn |S Thc meyer wercuminans+.ot
EDV (cemprenoaa )
tthe ww Me (tes of Veneay BICom Hace
fo We heart funiinme
T Showa >= caraial ourpur
. Fa ‘
Tbicoanvoiume (fiilin 5 Pressure)
5 Con Tal ven dus pressure/Vight anal
presSure (forward Pressure j
> Sthous tone ¥ He CAPACiTY OF Vane to
hei ct blood
= Seeictal muscve pump
“'eSpiratory Pume.
ls
Ty NRRR RE
nmerenrmrenmnrnrnnnAnReaRAR Pp
WSead kd ke deebadd bbb odd oe i ee
Con tract ty
**efers to He MOMOpTENSeTArS of the heart
71 6 he” denremp RMN RENERITMIeNRINNANANTRIMEANTE
Safina iro sures pretoad
Aepen dant a muscie Mevesy QU
toon The Ca2t con centre nc?
ry te connect
Wnich (o aepenac
CretieeetuiNS) Name me SSS
rBbitrload
s the force againut Wercmi which WC
V (CAI GAN GERI CLOMNO SIU
“Nomally mise presgare tyin Mme avttrics
sca Ch VENICE Mugt Develop €nov% force on
Wall Tenviet To exceed Miy precéurt in oracr
TO elect blood (Ate these artcriigy“COmparca te Me want ven miele ¢ rm
VENT ICle HAY
PARMCI TAME Han RY Wall.
~ Geog ESSOPEROR < rolvac mu sce
con Tacnon geRere aa
Aer Bie pathway /
*‘ Myecavatad iafracy arc far more commen
SA Le Et Venmicic Than ngnr wecawe ot The
Aicater Op requiremen™ here FOr Aceobic
Mmietaborvam
“be{tven tricular nypermoephy ws a Siagn Of
an Overmoare ea near,
Tre Caravac cycie
"one comptcte heart bear
* ONPIGVIZA' AWG! sylesele + Aiauiore *% VEN Mieulavy
suey
CANA C Muccite Muut Aepolarive oetorc iy
CAN CNWACT 4 (Epolanut befac (T can relax
SO eter cauevenm precede mechani Gl
events
(Heat has autornyummicrylaue ro cnnodcs:
Aepolan oan scquence
“Of node > GH atial muscic > RVNOAT
Catiay) > amiovenmicuiar bundle >
RAL bundic brancnc > Purkinje forty
SS VCNT I culay mudd |
~The Spreacmont Le
Mivougn THe heart.
“SA Node Qencratts impuldc aviena,
KxXCitanon begins
~*mpuVve dactayoa at AVnoac
nrerorempnrienrnnnaAranAanhhAhhRrtmrmtemraARPrerep Pee
IT7 _Umipultoxmierssens ro heart apex, vera mar
fx citanon Pega?
— ¥ cinmicanmesienireln OANeS IPSEC
FAT ial repotariganen eccuty AUWINgG Vent lay
arpotariganen.
HeReaeepae eee eed be eae oe ea+ THGRINGETAISING innermost Taye”
[~emnaomeium
»] — besmentine
9% 4 = tamina propria co Taye)
(_siatemna! erasne membrane Penesmarce
~lagu ef clastic fibres
meaate Layer
~SMooMm muscte cetly arangea circularity
around bicca vessi¢
= ehagne membianc( cxtorne?
Tsmeetm musa
AsO conu tri Chen -SMeCOM muAscred contect,
WOO risrotegu of ariciicy VON
ACCVCOIT DLCOA MS
~VasoaiiaTIon Smeem Must relax,
| gute Cr ictambo, 622Chom
= ecutcemost taytr (daven tie)
7 Conneenve Mesue
a Naricy frem aense regular CT Near he
vessel T 1e8Cs8 CT Aneh merge wim
Surcunaing CT.
AT AN artcne) tein) hove Same B cayer)
intima, meaia 4 externa
CAE CUE etal OND
= eg acita * majo' branches
- clagne Hssuc
7 cxeand 4 veco'!
7 Are pressure veservoivs
Taka comaucnng arrernicr
“tunica GIBB run Ca yaaa,
TyoCe eaummmee
nHnooenrnnapnartpePRReReRHRRHRARRAR RR
Itee ee ee ee ee
“MUS cutarn autericu Cg mearcam sized arenes
TAihwewWall J - PS nayers of muscle
TUnacrge vasoconsTICNa@ + vaso ar alanm
~ ata qilgmmeUnnig avTees
- RAMANA A. « (mime Cour te i” )
* QWNEVMIEIED smal) muscular avtevi cd
~ HECHMIAGIRG NA S2 < wim guecubuistes”
of Wan tage re Fer meal qeecriores
= GENRE IONE 4 (ERIE
Vermns ¢ Vente)
Meine ents A eee
7 VEIN
very Gmativeinyg aor That drain capillary
network
=chacmeial cel) 4 Casement Membrane
With fea smooth music cud
~Ry Alametey incrcasts, ameunt of smeeth
TARTANA cy
_GETRS
Ge cTamn US Obes | Cols RONnATAMI NSC Y CY -
AAALNON Of FuNnicAa aAVeNNA
— Mare vatves, min waite 4 Large tumeny
— very compiient 2u% More Man avterics
7 capacitance vewscts of cicculatian “neice
ALOT OF DICTA ar (OH Pressure
Capitlarves
+ GopiWaticy
= VEX SMe vessels C410 micreny )
= enaoMeciial cells Ging on abovemenr
membrane 4 aeticatce layer of CT.
7 designe a for Vapra exchange of
Nutrients 4metapciites bench bicce 4
Inteven nel Aurct
—Sups Tances meve Mreugh capillary wall——_“Aiaeal a eSLOG.0
~ OPC TSIEN) t STATES TEMEGSINK <
Mote cul) typo R SIAM ItRnIZEASINTISGIN
* _ CEWeTE RM SITAR In OL CONT 7
poss eenENAY oF Se NS
beteeen enaomeivat C¢e\lO
_ TAVee TYpeEu!
>€S8 THUCLYS
~RISmIgapl e fer me acute conto of MAP
S adjustment in se@pimmA) oy seme’
repleceu Aihevmency
TPS Ss ee mm me mm
ail eLe
onHawg adda kb ged dg a ea ee ee ew ow eh
7_ 2. ORIEN
ta djustmen (6 Over MOSNUMMSTSy J bY
Te
aN cypanaing blood volume Pracsea MAP
veAucect
A fating blocs votume = Vaan MAP
+ COMA OVENSTERNEVNCERINE in Th ¢ RETEUNENS BISA Seite”
YS ESSER NSU FEV overal MINPTEAUereny
~Caoraiovascutay centt<
T vasomotor ceawe
Higner ens Baroreceptors qnemose cee Tot
centres oS
TPoavaiovaccutaves
centwe
CAV Osea uiaroly vasomotor cenwe
centre
L i
Heart bpliooct Vvewsei >
Showt rerum MAP contre |_mecnanismys
+ Bavoreceprovivettce:
~SpIPIONCU in i meRESNEMSyecencave io MWR
TOC THe Aaily VeunIEINEN TREN TEBE YBN On:
+ Baroreteptecs are!
= hugniP RECS GS WETeR ecc prow eeetieaiiing hc
COMMON, 7 GAIPEURTENIC IIS 5
BANE HCA by avferentieMthemmsencory
NEWWEL fONeAVENSWarcver Ceawe.
+ APFEVERT SENTEG (m pulses PASS te me CVE cen EA
ater ‘
= VaigewTSYyMpaMmen c ANS Charge 16 The Heart from
The cardio ve gqulatory Centre > EWERSET MIMI OY
7 _SYPAPATMEHIOMVACSERRISINESY Aiscnarg~< t¢ Bicct
Vesseis fram me varometor ceawe 3 EWRRBEUIS
Tres.SUhiciie atonene prem) cetiee
vmMare
L
as ee ee
J
Viatferent im puiSau ta eufter sensory Cemvey
L
meastia caratiovascutay
RRP RE
centve
Cat aroreguiatery centre V ASIN ONONS Sen wre
pchomenee
Symplametie (+) bymeatre
25
va gus(-) eee Vasoc On Str ichon
Y
SA noae vVenticies ven avter ote J
eontrach ty deapacitance MNesistance
toe oe
K— aco —
Sree ae NI Bi
nus
Dect ar nice ATER
s Barerece picts in me carond sinus + aorme aren
men ter etoca presoue
5
=
r=
re
=
&
: e
e
=
zs
e
Me meauua obiengeta.
1 NNGNGOV SAN RAC YIMP anemic STmMUtaton of me Heart
aeereoues Me Reart rare.
Aan
1 mew TAIO SMEG M pate CSAMUIGWEE of me block vewse
ARSMSet tet m MAP can Wot MecNanigm >
we le ee
— meee
= \_ 7 AIDEN “CHE Keawe Te FIMIRP
ANUP Sccietect BY THe cardiac atia vhen Bieom
Vewme Ses couse KAUSEREIRSS , GRENIER 5
Thave Goput re me caraiovavcutay centre causing
he eee , (flea =* <
= Situanon , (CMEANENSSONASE (cacy
Es iO HSRVEQUEEMNOS WENIESUEIONCC, » reaucecnpH)
tn Mme medulla chiengara, snmutarey near.
HO vavomoter cenme, Wnicn GIRNBUUee-
—__S9 Be eee
Leong term MAP meen anism?
2 bY the 7Ahe Ki cincy Via renat cone: of pico
votume
one
* ANNICIEH exepenee rena mechaniwms
“ nievieeweeEUSESIVElGM « > inkveateR cRaIERUAL
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