Creon Coupons & Prices

Creon (pancrelipase) is an FDA-approved medication that is prescribed to patients with certain pancreatic conditions like exocrine pancreatic insufficiency (EPI), cystic fibrosis, or chronic pancreatitis. It provides certain enzymes needed for digestion. There is no generic version of Creon for sale. The retail price of Creon is $1,674.71 for 100, 36000-114000unit capsules delayed release particles of Creon, but you could pay $1,182.01 for 100, 36000-114000unit capsules delayed release particles with SingleCare's free coupons.

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21 capsule delayed release particles3000-9500unitEdit

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Creon coupon at Walgreens Pharmacy
$1185.01
$ 1,182
$3 off with signupwith signup

Show this free card to your pharmacist.

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Creon coupon at Kroger Pharmacy
$1197.39
$ 1,194
$3 off with signupwith signup

Save an extra $3 on any eligible prescription! Sign up for free

Members can save even more
and it's free to join

Creon coupon at Harris Teeter Pharmacy
$1197.39
$ 1,194
$3 off with signupwith signup
Creon coupon at CVS Pharmacy
$1261.97
$ 1,259
$3 off with signupwith signup
Creon coupon at Publix Pharmacy
$1285.62
$ 1,283
$3 off with signupwith signup
Creon coupon at Costco Pharmacy
$1298.11
$ 1,295
$3 off with signupwith signup
$ 1,325

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 11/01/2025

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About Creon

Creon (pancrelipase) is an FDA-approved medication that is prescribed to patients with certain pancreatic conditions like exocrine pancreatic insufficiency (EPI), cystic fibrosis, or chronic pancreatitis. It provides certain enzymes needed for digestion. There is no generic version of Creon for sale. The retail price of Creon is $1,674.71 for 100, 36000-114000unit capsules delayed release particles of Creon, but you could pay $1,182.01 for 100, 36000-114000unit capsules delayed release particles with SingleCare's free coupons.

Creon Price History & Information

Price History for Creon

100 count, capsule delayed release particles, 36000-114000unit

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 1-Month Prices for Creon

100 count, capsule delayed release particles, 36000-114000unit
PharmacyCreon Retail PriceCreon SingleCare Price
CVS Pharmacy$1522.00$1250.00
Walmart$1550.00$1479.00
Walgreens$1550.00$1370.00
Kroger Pharmacy$1549.00$1197.00

These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Creon

Creon (pancrelipase) is an FDA-approved medication that is prescribed to patients with certain pancreatic conditions like exocrine pancreatic insufficiency (EPI), cystic fibrosis, or chronic pancreatitis. It provides certain enzymes needed for digestion. There is no generic version of Creon for sale. The retail price of Creon is $1,674.71 for 100, 36000-114000unit capsules delayed release particles of Creon, but you could pay $1,182.01 for 100, 36000-114000unit capsules delayed release particles with SingleCare's free coupons.

Creon FAQs

Medically reviewed by Anne JacobsonMD, MPH
Board-Certified Family Physician

How much does Creon cost without insurance?

If you are paying out-of-pocket without insurance, the average cash price of Creon would be $1,674.71 for 100, 36000-114000unit capsules delayed release particles.

SingleCare provides free Creon coupons to enable patients to receive prescription savings of up to 80%. You can visit a participating pharmacy to inquire whether your prescription discount card is accepted. If it is, you could reduce your total amount due to only $1,182.01 for 100, 36000-114000unit capsules delayed release particles.

How much does Creon cost with insurance?

Your health insurance plan may provide you with coverage for this prescription drug. However, the copay of Creon will vary based on your insurance plan. You can discuss your savings with a pharmacist at any of SingleCare's participating drugstores to compare your savings options. In some instances, SingleCare may be less costly than your insurance. Contact your health insurance plan for more information about commercial prescription insurance coverage of Creon. 

Does Medicare cover Creon, and how much does it cost?

The majority of Medicare Part D and Medicare Advantage plans cover Creon, but your copay will depend on your plan and coverage stage. SingleCare's lowest price of $1,182.01 for 100, 36000-114000unit capsules delayed release particles could very well be lower than your Medicare copay. You can use your Creon savings card from SingleCare at local pharmacies to compare prices between Medicare and coupons from SingleCare.

How much does Creon cost with Medicaid? 

Medicaid coverage will vary by state. Many state Medicaid plans cover Creon, but check your state Medicaid formulary to know for sure.

Ways to save on Creon

  • Print or download a SingleCare discount card to save on your monthly Creon cost.

  • Explore the manufacturer’s financial assistance program

  • Look into different health insurance options. Find out whether Creon is included in the formulary.

  • Check out the formulary for different Medicare Part D or Medicare Advantage plans.

  • Ask your healthcare provider about other pancreatic enzyme alternatives.

Is there a generic for Creon?

Creon is a brand-name drug. Presently, there is no generic substitute for Creon.

What are cheaper alternatives for Creon?

The drug name for Creon is pancrelipase. In addition to Creon, pancrelipase is also manufactured under the brand names:

Drug prices fluctuate, but in general, Zenpep and Pertzye are more expensive than Creon, while Viokace and Pancreaze are less expensive. Talk with your healthcare provider about the version of pancrelipase that will be most effective and affordable for you. You can compare prices between the brand name versions of pancrelipase here.

Medically reviewed by Anne JacobsonMD, MPH
Board-Certified Family Physician

Anne Jacobson, MD, MPH, is a board-certified family physician, writer, editor, teacher, and consultant. She is a graduate of University of Wisconsin School of Medicine and Public Health, and trained at West Suburban Family Medicine in Oak Park, Illinois. She later completed a fellowship in community medicine at PCC Community Wellness and a master's in Public Health at the University of Illinois-Chicago. She lives with her family near Chicago.

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Where are Creon coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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