Wellbutrin SR (bupropion) is an FDA-approved oral depression medication that is used to treat major depressive disorders such as depression and bipolar disorder and seasonal affective disorder. Wellbutrin SR is a brand-name drug. Bupropion is the generic version of Wellbutrin SR and is also available to consumers. The cash price of Wellbutrin SR is approximately $562.58 60, 150mg tablet extended release 12 hours of Wellbutrin SR but you can save and pay $6.20 for 60, 150mg tablets of generic Wellbutrin SR with a free coupon from SingleCare.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 10/31/2025
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Wellbutrin SR (bupropion) is an FDA-approved oral depression medication that is used to treat major depressive disorders such as depression and bipolar disorder and seasonal affective disorder. Wellbutrin SR is a brand-name drug. Bupropion is the generic version of Wellbutrin SR and is also available to consumers. The cash price of Wellbutrin SR is approximately $562.58 60, 150mg tablet extended release 12 hours of Wellbutrin SR but you can save and pay $6.20 for 60, 150mg tablets of generic Wellbutrin SR with a free coupon from SingleCare.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Wellbutrin Sr Retail Price | Bupropion Hcl Er (Sr) Retail Price | Bupropion Hcl Er (Sr) SingleCare Price | 
|---|---|---|---|
| CVS Pharmacy | $564.00 | $96.74 | $35.22 | 
| Walmart | - | $35.83 | $29.40 | 
| Walgreens | $601.80 | $14.64 | $10.95 | 
| Kroger Pharmacy | $597.00 | $91.31 | $9.52 | 
| Albertsons Pharmacy | - | $86.60 | $16.20 | 
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Wellbutrin SR (bupropion) is an FDA-approved oral depression medication that is used to treat major depressive disorders such as depression and bipolar disorder and seasonal affective disorder. Wellbutrin SR is a brand-name drug. Bupropion is the generic version of Wellbutrin SR and is also available to consumers. The cash price of Wellbutrin SR is approximately $562.58 60, 150mg tablet extended release 12 hours of Wellbutrin SR but you can save and pay $6.20 for 60, 150mg tablets of generic Wellbutrin SR with a free coupon from SingleCare.
The average retail price of Wellbutrin SR can be costly at $562.58 $562.58 60, 150mg tablet extended release 12 hours of Wellbutrin SR, without insurance or coupons. However, $6.20 for 60, 150mg tablets of generic Wellbutrin SR could be your discounted price when you use our free discount card from SingleCare.
Ask your pharmacist to calculate your Wellbutrin SR price with insurance since copays vary by health insurance plan. With a SingleCare savings card, you could pay as little as $6.20 for 60, 150mg tablets of generic Wellbutrin SR for your prescription of Wellbutrin SR at participating pharmacies such as CVS Pharmacy, Walmart, and Duane Reed.
Wellbutrin SR is typically covered by Medicare. The typical copay of this prescription drug with Medicare is anywhere from $0-$47 but SingleCare may be a cheaper alternative to Medicare.
Wellbutrin SR is a brand-name drug that is manufactured by GlaxoSmithKline. Aplenzin, Zyban, Forfivo XL, and Wellbutrin Xl are all related brand-name drugs. The generic version of Wellbutrin SR is bupropion HCl.
Wellbutrin SR is a prescription medication that is used to treat major depressive disorders and seasonal affective disorders. It is available in the form of a sustained-release and extended-release tablets. Wellbutrin SR is thought to help restore the balance of certain natural substances in your brain.
Wellbutrin SR is taken twice a day. In the case of a missed dose take the next tablet at the regular time to reduce dose-related risk of seizure. The daily dose should not be changed without a doctor's approval as it may increase your risk of seizure. It is not recommended to chew, split or crush Wellbutrin SR sustained-release or extended-release tablets as adverse effects may occur.
Use Wellbutrin SR only as prescribed by a doctor or healthcare professional. It is not recommended to use MAOIs or Monoamine oxidase inhibitors like methylene blue injection, linezolid, phenelzine, and rasagiline within 14 days of taking Wellbutrin SR as dangerous drug interactions may occur.
Using Wellbutrin SR and alcohol increases the risk of seizures as well as having a head injury, especially if you have certain medical conditions or use certain drugs. It is not recommended to take Wellbutrin SR if you have a seizure disorder, an eating disorder such as anorexia nervosa or if you have suddenly stopped using alcohol, seizure medication, or a sedative. Caution is advised when breastfeeding. Tell your doctor or health care provider if you have diabetes, heart disease, high blood pressure, kidney problems, liver disease, history of heart attack, or any mental health problems before taking Wellbutrin SR. Inform your doctor if you use ritonavir, carbamazepine, or tamoxifen. Wellbutrin may be used with a nicotine patch. Read all medication guides provided by your doctor.
Wellbutrin SR is habit-forming and its extended use is not recommended. Some common side effects of Wellbutrin SR include trouble sleeping, irritability, palpitations, and increased heart rate. Some other possible side effects of this drug include blurred vision, constipation, change in sense of taste, drowsiness, hives, sore throat, and dry mouth.
Some rare side effects of Wellbutrin SR are confusion, false beliefs, and trouble concentrating. Smoking cessation may also cause new or worsen mental health problems e.g. depressed mood.
Contact your doctor or health care provider right away for medical advice if you experience serious side effects including unusual weight loss or weight gain, panic attacks, and mental or mood changes such as unusual changes in behavior or thinking or suicidal thoughts especially in young adults.
Contact a poison control center if you suspect an allergic reaction or have other serious symptoms. Wellbutrin SR may also cause adverse events. This is not a complete list of side effects.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved