RNGTT
RNGTT| RNGTT | |||||||||||||||||||||||||
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| 식별자 | |||||||||||||||||||||||||
| 에일리어스 | RNGTT, CAP1A, HCE, HCE1, hCAP, RNA구아릴전달효소 및 5'-인산가수분해효소 | ||||||||||||||||||||||||
| 외부 ID | OMIM : 603512 MGI : 1329041 HomoloGene : 37851 GenCard : RNGTT | ||||||||||||||||||||||||
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| 맞춤법 | |||||||||||||||||||||||||
| 종. | 인간 | 마우스 | |||||||||||||||||||||||
| 엔트레즈 | |||||||||||||||||||||||||
| 앙상블 | |||||||||||||||||||||||||
| 유니프로트 | |||||||||||||||||||||||||
| RefSeq(mRNA) | |||||||||||||||||||||||||
| RefSeq(단백질) | |||||||||||||||||||||||||
| 장소(UCSC) | Chr 6: 88.61 ~88.96 Mb | Chr 4: 33.31 ~33.5 Mb | |||||||||||||||||||||||
| PubMed 검색 | [3] | [4] | |||||||||||||||||||||||
| 위키데이터 | |||||||||||||||||||||||||
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mRNA-capping 효소는 RNGTT [5][6][7]유전자에 의해 인간에게 암호화되는 단백질이다.
레퍼런스
- ^ a b c GRCh38: 앙상블 릴리즈 89: ENSG00000111880 - 앙상블, 2017년 5월
- ^ a b c GRCm38: 앙상블 릴리즈 89: ENSMUSG000028274 - 앙상블, 2017년 5월
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Pillutla RC, Shimamoto A, Furuichi Y, Shatkin AJ (Jan 1999). "Human mRNA capping enzyme (RNGTT) and cap methyltransferase (RNMT) map to 6q16 and 18p11.22-p11.23, respectively". Genomics. 54 (2): 351–3. doi:10.1006/geno.1998.5604. PMID 9828141.
- ^ Yamada-Okabe T, Doi R, Shimmi O, Arisawa M, Yamada-Okabe H (May 1998). "Isolation and characterization of a human cDNA for mRNA 5'-capping enzyme". Nucleic Acids Res. 26 (7): 1700–6. doi:10.1093/nar/26.7.1700. PMC 147440. PMID 9512541.
- ^ "Entrez Gene: RNGTT RNA guanylyltransferase and 5'-phosphatase".
추가 정보
- Yue Z, Maldonado E, Pillutla R, et al. (1998). "Mammalian capping enzyme complements mutant Saccharomyces cerevisiae lacking mRNA guanylyltransferase and selectively binds the elongating form of RNA polymerase II". Proc. Natl. Acad. Sci. U.S.A. 94 (24): 12898–903. doi:10.1073/pnas.94.24.12898. PMC 24235. PMID 9371772.
- Tsukamoto T, Shibagaki Y, Murakoshi T, et al. (1998). "Cloning and characterization of two human cDNAs encoding the mRNA capping enzyme". Biochem. Biophys. Res. Commun. 243 (1): 101–8. doi:10.1006/bbrc.1997.8038. PMID 9473487.
- Pillutla RC, Yue Z, Maldonado E, Shatkin AJ (1998). "Recombinant human mRNA cap methyltransferase binds capping enzyme/RNA polymerase IIo complexes". J. Biol. Chem. 273 (34): 21443–6. doi:10.1074/jbc.273.34.21443. PMID 9705270.
- Wen Y, Shatkin AJ (1999). "Transcription elongation factor hSPT5 stimulates mRNA capping". Genes Dev. 13 (14): 1774–9. doi:10.1101/gad.13.14.1774. PMC 316881. PMID 10421630.
- Chiu YL, Coronel E, Ho CK, et al. (2001). "HIV-1 Tat protein interacts with mammalian capping enzyme and stimulates capping of TAR RNA". J. Biol. Chem. 276 (16): 12959–66. doi:10.1074/jbc.M007901200. PMID 11278368.
- Chiu YL, Ho CK, Saha N, et al. (2002). "Tat stimulates cotranscriptional capping of HIV mRNA". Mol. Cell. 10 (3): 585–97. doi:10.1016/S1097-2765(02)00630-5. PMID 12408826.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Zhou M, Deng L, Kashanchi F, et al. (2004). "The Tat/TAR-dependent phosphorylation of RNA polymerase II C-terminal domain stimulates cotranscriptional capping of HIV-1 mRNA". Proc. Natl. Acad. Sci. U.S.A. 100 (22): 12666–71. doi:10.1073/pnas.1835726100. PMC 240675. PMID 14569024.
- Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence Comparison of Human and Mouse Genes Reveals a Homologous Block Structure in the Promoter Regions". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMC 515316. PMID 15342556.
- Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
외부 링크
- PDBe-KB는 인간 mRNA-caping 효소(RNGTT)에 대한 PDB에서 사용 가능한 모든 구조 정보의 개요를 제공합니다.