UDP-글루코노실전달효소 1-3은 인간에게 UGT1A3 유전자에 의해 암호화된 효소다.[4][5][6]
이 유전자는 스테로이드, 빌리루빈, 호르몬, 약물 등 작은 지방질 분자를 수용성, 배설성 대사물로 변형시키는 글루쿠로니드화 경로의 효소인 UDP-글루쿠로노실전달효소를 인코딩한다. 이 유전자는 여러 UDP-글루쿠로노실 전이를 암호화하는 복잡한 위치의 일부다. 로커스는 13개의 독특한 첫 번째 엑손과 4개의 공통 엑손들을 포함한다. 다른 첫 번째 엑손 중 4개는 유사 유전자로 간주된다. 나머지 9개의 5' exon 각각은 4개의 공통 exon에 분할되어 서로 다른 N-termini와 동일한 C-termini를 가진 9개의 단백질이 생성될 수 있다. 각 첫 번째 엑손은 기판 결합 사이트를 암호화하고, 자체 프로모터에 의해 규제된다. 이 효소의 기질에는 에스트론, 2-히드록시스트론, 벤조피렌 대사물이 포함된다.[7][8][9]
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