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Thomas Lengauer
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- affiliation: University Hospital Cologne, Germany
- affiliation (former): Max-Planck-Institut for Informatics, Saarbrücken, Germany
- award (2003): Konrad Zuse Medal
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2020 – today
- 2023
- [i3]Giulia Di Teodoro, Martin Pirkl, Francesca Incardona, Ilaria Vicenti, Anders Sönnerborg, Rolf Kaiser, Laura Palagi, Maurizio Zazzi, Thomas Lengauer:
Incorporating temporal dynamics of mutations to enhance the prediction capability of antiretroviral therapy's outcome for HIV-1. CoRR abs/2311.04846 (2023)
2010 – 2019
- 2018
- [j123]Matthias Döring, Joachim Büch, Georg Friedrich, Alejandro Pironti, Prabhav Kalaghatgi, Elena Knops, Eva Heger, Martin Obermeier, Martin Däumer, Alexander Thielen, Rolf Kaiser, Thomas Lengauer, Nico Pfeifer:
geno2pheno[ngs-freq]: a genotypic interpretation system for identifying viral drug resistance using next-generation sequencing data. Nucleic Acids Res. 46(Webserver-Issue): W271-W277 (2018) - 2017
- [j122]Felipe Albrecht, Markus List, Christoph Bock, Thomas Lengauer:
DeepBlueR: large-scale epigenomic analysis in R. Bioinform. 33(13): 2063-2064 (2017) - [j121]Bonnie Berger, Terry Gaasterland, Thomas Lengauer, Christine A. Orengo, Bruno Gaëta, Scott Markel, Alfonso Valencia:
ISCB's initial reaction to New England Journal of Medicine editorial on data sharing. Bioinform. 33(18): 2968 (2017) - [j120]Prabhav Kalaghatgi, Thomas Lengauer:
Computing phylogenetic trees using topologically related minimum spanning trees. J. Graph Algorithms Appl. 21(6): 1003-1025 (2017) - [i2]Prabhav Kalaghatgi, Thomas Lengauer:
Selecting optimal minimum spanning trees that share a topological correspondence with phylogenetic trees. CoRR abs/1701.02844 (2017) - 2016
- [j119]Felipe Albrecht, Markus List, Christoph Bock, Thomas Lengauer:
DeepBlue epigenomic data server: programmatic data retrieval and analysis of epigenome region sets. Nucleic Acids Res. 44(Webserver-Issue): W581-W586 (2016) - [j118]Bonnie Berger, Terry Gaasterland, Thomas Lengauer, Christine A. Orengo, Bruno Gaëta, Scott Markel, Alfonso Valencia:
ISCB's Initial Reaction to The New England Journal of Medicine Editorial on Data Sharing. PLoS Comput. Biol. 12(3) (2016) - 2015
- [j117]Peter Ebert, Fabian Müller, Karl Nordström, Thomas Lengauer, Marcel H. Schulz:
A general concept for consistent documentation of computational analyses. Database J. Biol. Databases Curation 2015 (2015) - [j116]Peter D. Karp, Bonnie Berger, Diane E. Kovats, Thomas Lengauer, Michal Linial, Pardis Sabeti, Winston Hide, Burkhard Rost:
Message from the ISCB: ISCB Ebola award for important future research on the computational biology of Ebola virus. Bioinform. 31(4): 616-617 (2015) - [j115]Peter D. Karp, Bonnie Berger, Diane E. Kovats, Thomas Lengauer, Michal Linial, Pardis Sabeti, Winston Hide, Burkhard Rost:
ISCB Ebola Award for Important Future Research on the Computational Biology of Ebola Virus. PLoS Comput. Biol. 11(1) (2015) - [j114]Thomas Lengauer, Ruth Nussinov:
How to Write a Presubmission Inquiry. PLoS Comput. Biol. 11(2) (2015) - 2014
- [j113]Anna Katharina Hildebrandt, Matthias Dietzen, Thomas Lengauer, Hans-Peter Lenhof, Ernst Althaus, Andreas Hildebrandt:
Efficient computation of root mean square deviations under rigid transformations. J. Comput. Chem. 35(10): 765-771 (2014) - [j112]Mazen Ahmad, Olga V. Kalinina, Thomas Lengauer:
Entropy gain due to water release upon ligand binding. J. Cheminformatics 6(S-1): 35 (2014) - [j111]Matthias Dietzen, Elena Zotenko, Andreas Hildebrandt, Thomas Lengauer:
Correction to On the Applicability of Elastic Network Normal Modes in Small-Molecule Docking. J. Chem. Inf. Model. 54(12): 3453 (2014) - [j110]Daniel Becker, Pavlo Lutsik, Peter Ebert, Christoph Bock, Thomas Lengauer, Jörn Walter:
BiQ Analyzer HiMod: an interactive software tool for high-throughput locus-specific analysis of 5-methylcytosine and its oxidized derivatives. Nucleic Acids Res. 42(Webserver-Issue): 501-507 (2014) - 2013
- [j109]Laura Tolosi, Jessica Theißen, Konstantin Halachev, Barbara Hero, Frank Berthold, Thomas Lengauer:
A method for finding consensus breakpoints in the cancer genome from copy number data. Bioinform. 29(14): 1793-1800 (2013) - [j108]Katarzyna Bozek, Thomas Lengauer, Saleta Sierra, Rolf Kaiser, Francisco S. Domingues:
Analysis of Physicochemical and Structural Properties Determining HIV-1 Coreceptor Usage. PLoS Comput. Biol. 9(3) (2013) - [j107]Thomas Lengauer, Ruth Nussinov:
New Methods Section in PLOS Computational Biology. PLoS Comput. Biol. 9(3) (2013) - [j106]Sven-Eric Schelhorn, Matthias Fischer, Laura Tolosi, Janine Altmüller, Peter Nürnberg, Herbert Pfister, Thomas Lengauer, Frank Berthold:
Sensitive Detection of Viral Transcripts in Human Tumor Transcriptomes. PLoS Comput. Biol. 9(10) (2013) - 2012
- [j105]Nico Pfeifer, Thomas Lengauer:
Improving HIV coreceptor usage prediction in the clinic using hints from next-generation sequencing data. Bioinform. 28(18): 589-595 (2012) - [j104]Burkhard Rost, Terry Gaasterland, Thomas Lengauer, Michal Linial, Scott Markel, B. J. Morrison McKay, Reinhard Schneider, Paul Horton, Janet Kelso:
Paving the future: finding suitable ISMB venues. Bioinform. 28(19): 2556-2559 (2012) - [j103]Matthias Dietzen, Elena Zotenko, Andreas Hildebrandt, Thomas Lengauer:
On the Applicability of Elastic Network Normal Modes in Small-Molecule Docking. J. Chem. Inf. Model. 52(3): 844-856 (2012) - [c73]Jasmina Bogojeska, Daniel Stöckel, Maurizio Zazzi, Rolf Kaiser, Francesca Incardona, Michal Rosen-Zvi, Thomas Lengauer:
History-alignment models for bias-aware prediction of virological response to HIV combination therapy. AISTATS 2012: 118-126 - 2011
- [j102]Laura Tolosi, Thomas Lengauer:
Classification with correlated features: unreliability of feature ranking and solutions. Bioinform. 27(14): 1986-1994 (2011) - [j101]Martin Däumer, Rolf Kaiser, Rolf Klein, Thomas Lengauer, Bernhard Thiele, Alexander Thielen:
Genotypic tropism testing by massively parallel sequencing: qualitative and quantitative analysis. BMC Medical Informatics Decis. Mak. 11: 30 (2011) - [j100]Pavlo Lutsik, Lars Feuerbach, Julia Arand, Thomas Lengauer, Jörn Walter, Christoph Bock:
BiQ Analyzer HT: locus-specific analysis of DNA methylation by high-throughput bisulfite sequencing. Nucleic Acids Res. 39(Web-Server-Issue): 551-556 (2011) - 2010
- [j99]André Altmann, Laura Tolosi, Oliver Sander, Thomas Lengauer:
Permutation importance: a corrected feature importance measure. Bioinform. 26(10): 1340-1347 (2010) - [j98]Jasmina Bogojeska, Steffen Bickel, André Altmann, Thomas Lengauer:
Dealing with sparse data in predicting outcomes of HIV combination therapies. Bioinform. 26(17): 2085-2092 (2010) - [j97]Andreas Schlicker, Thomas Lengauer, Mario Albrecht:
Improving disease gene prioritization using the semantic similarity of Gene Ontology terms. Bioinform. 26(18) (2010) - [j96]Kirsten Roomp, Iris Antes, Thomas Lengauer:
Predicting MHC class I epitopes in large datasets. BMC Bioinform. 11: 90 (2010) - [j95]Thomas Lengauer, André Altmann, Alexander Thielen, Rolf Kaiser:
Chasing the AIDS virus. Commun. ACM 53(3): 66-74 (2010) - [j94]Dorothea Emig, Nathan Salomonis, Jan Baumbach, Thomas Lengauer, Bruce R. Conklin, Mario Albrecht:
AltAnalyze and DomainGraph: analyzing and visualizing exon expression data. Nucleic Acids Res. 38(Web-Server-Issue): 755-762 (2010)
2000 – 2009
- 2009
- [j93]Hagen Blankenburg, Robert D. Finn, Andreas Prlic, Andrew M. Jenkinson, Fidel Ramírez, Dorothea Emig, Sven-Eric Schelhorn, Joachim Büch, Thomas Lengauer, Mario Albrecht:
DASMI: exchanging, annotating and assessing molecular interaction data. Bioinform. 25(10): 1321-1328 (2009) - [j92]Thomas Lengauer, André Altmann, Alexander Thielen:
Bioinformatische Unterstützung der Auswahl von HIV-Therapien. Inform. Spektrum 32(4): 320-331 (2009) - [c72]Juliane Perner, André Altmann, Thomas Lengauer:
Semi-Supervised Learning for Improving Prediction of HIV Drug Resistance. GCB 2009: 55-65 - 2008
- [j91]Christoph Bock, Thomas Lengauer:
Computational epigenetics. Bioinform. 24(1): 1-10 (2008) - [j90]Yassen Assenov, Fidel Ramírez, Sven-Eric Schelhorn, Thomas Lengauer, Mario Albrecht:
Computing topological parameters of biological networks. Bioinform. 24(2): 282-284 (2008) - [j89]Jasmina Bogojeska, Adrian Alexa, André Altmann, Thomas Lengauer, Jörg Rahnenführer:
Rtreemix: an R package for estimating evolutionary pathways and genetic progression scores. Bioinform. 24(20): 2391-2392 (2008) - [j88]Dorothea Emig, Melissa S. Cline, Thomas Lengauer, Mario Albrecht:
Integrating expression data with domain interaction networks. Bioinform. 24(21): 2546-2548 (2008) - [j87]Jasmina Bogojeska, Thomas Lengauer, Jörg Rahnenführer:
Stability analysis of mixtures of mutagenetic trees. BMC Bioinform. 9 (2008) - [j86]Dorothea Emig, Melissa S. Cline, Karsten Klein, Anne Kunert, Petra Mutzel, Thomas Lengauer, Mario Albrecht:
Integrative Visual Analysis of the Effects of Alternative Splicing on Protein Domain Interaction Networks. J. Integr. Bioinform. 5(2) (2008) - [j85]Nils Weinhold, Oliver Sander, Francisco S. Domingues, Thomas Lengauer, Ingolf Sommer:
Local Function Conservation in Sequence and Structure Space. PLoS Comput. Biol. 4(7) (2008) - [c71]Oliver Sander, Francisco S. Domingues, Hongbo Zhu, Thomas Lengauer, Ingolf Sommer:
Structural Descriptors of Protein-Protein Binding Sites. APBC 2008: 79-88 - [c70]Sven-Eric Schelhorn, Thomas Lengauer, Mario Albrecht:
An integrative approach for predicting interactions of protein regions. ECCB 2008: 35-41 - [c69]Steffen Bickel, Jasmina Bogojeska, Thomas Lengauer, Tobias Scheffer:
Multi-task learning for HIV therapy screening. ICML 2008: 56-63 - [c68]Michal Rosen-Zvi, André Altmann, Mattia Prosperi, Ehud Aharoni, Hani Neuvirth, Anders Sönnerborg, Eugen Schülter, Daniel Struck, Yardena Peres, Francesca Incardona, Rolf Kaiser, Maurizio Zazzi, Thomas Lengauer:
Selecting anti-HIV therapies based on a variety of genomic and clinical factors. ISMB 2008: 399-406 - [i1]Andreas Schlicker, Fidel Ramírez, Jörg Rahnenführer, Carola Huthmacher, Alejandro Pironti, Francisco S. Domingues, Thomas Lengauer, Mario Albrecht:
Applications of semantic similarity measures. Ontologies and Text Mining for Life Sciences 2008 - 2007
- [j84]Andreas Schlicker, Carola Huthmacher, Fidel Ramírez, Thomas Lengauer, Mario Albrecht:
Functional evaluation of domain-domain interactions and human protein interaction networks. Bioinform. 23(7): 859-865 (2007) - [j83]Francisco S. Domingues, Jörg Rahnenführer, Thomas Lengauer:
Conformational analysis of alternative protein structures. Bioinform. 23(23): 3131-3138 (2007) - [j82]Ingolf Sommer, Oliver Müller, Francisco S. Domingues, Oliver Sander, Joachim Weickert, Thomas Lengauer:
Moment invariants as shape recognition technique for comparing protein binding sites. Bioinform. 23(23): 3139-3146 (2007) - [j81]Oliver Sander, Tobias Sing, Ingolf Sommer, Andrew J. Low, Peter K. Cheung, P. Richard Harrigan, Thomas Lengauer, Francisco S. Domingues:
Structural Descriptors of gp120 V3 Loop for the Prediction of HIV-1 Coreceptor Usage. PLoS Comput. Biol. 3(3) (2007) - [j80]Thomas Lengauer, B. J. Morrison McKay, Burkhard Rost:
ISMB/ECCB 2007: The Premier Conference on Computational Biology. PLoS Comput. Biol. 3(5) (2007) - [j79]Christoph Bock, Jörn Walter, Martina Paulsen, Thomas Lengauer:
CpG Island Mapping by Epigenome Prediction. PLoS Comput. Biol. 3(6) (2007) - 2006
- [j78]Jochen Maydt, Thomas Lengauer:
Recco: recombination analysis using cost optimization. Bioinform. 22(9): 1064-1071 (2006) - [j77]Andrew E. Torda, Thomas Lengauer:
Editorial. Bioinform. 22(10): 1157 (2006) - [j76]Burkhard Heil, Jost Ludwig, Hella Lichtenberg-Fraté, Thomas Lengauer:
Computational recognition of potassium channel sequences. Bioinform. 22(13): 1562-1568 (2006) - [j75]Adrian Alexa, Jörg Rahnenführer, Thomas Lengauer:
Improved scoring of functional groups from gene expression data by decorrelating GO graph structure. Bioinform. 22(13): 1600-1607 (2006) - [j74]Oliver Sander, Ingolf Sommer, Thomas Lengauer:
Local protein structure prediction using discriminative models. BMC Bioinform. 7: 14 (2006) - [j73]Hongbo Zhu, Francisco S. Domingues, Ingolf Sommer, Thomas Lengauer:
NOXclass: prediction of protein-protein interaction types. BMC Bioinform. 7: 27 (2006) - [j72]Andreas Schlicker, Francisco S. Domingues, Jörg Rahnenführer, Thomas Lengauer:
A new measure for functional similarity of gene products based on Gene Ontology. BMC Bioinform. 7: 302 (2006) - [j71]Ingolf Sommer, Stefano Toppo, Oliver Sander, Thomas Lengauer, Silvio C. E. Tosatto:
Improving the quality of protein structure models by selecting from alignment alternatives. BMC Bioinform. 7: 364 (2006) - [j70]Dirk Neumann, Oliver Kohlbacher, Christian Merkwirth, Thomas Lengauer:
A Fully Computational Model for Predicting Percutaneous Drug Absorption. J. Chem. Inf. Model. 46(1): 424-429 (2006) - [j69]Andreas Kämper, Joannis Apostolakis, Matthias Rarey, Christel M. Marian, Thomas Lengauer:
Fully Automated Flexible Docking of Ligands into Flexible Synthetic Receptors Using Forward and Inverse Docking Strategies. J. Chem. Inf. Model. 46(2): 903-911 (2006) - [j68]Andreas Steffen, Andreas Kämper, Thomas Lengauer:
Flexible Docking of Ligands into Synthetic Receptors Using a Two-Sided Incremental Construction Algorithm. J. Chem. Inf. Model. 46(4): 1695-1703 (2006) - [c67]Kirsten Roomp, Niko Beerenwinkel, Tobias Sing, Eugen Schülter, Joachim Büch, Saleta Sierra-Aragon, Martin Däumer, Daniel Hoffmann, Rolf Kaiser, Thomas Lengauer, Joachim Selbig:
Arevir: A Secure Platform for Designing Personalized Antiretroviral Therapies Against HIV. DILS 2006: 185-194 - [c66]Andreas Schlicker, Carola Huthmacher, Fidel Ramírez, Thomas Lengauer, Mario Albrecht:
Functional Evaluation of Domain-Domain Interactions and Human Protein Interaction Networks. German Conference on Bioinformatics 2006: 115-126 - [c65]Iris Antes, Shirley W. I. Siu, Thomas Lengauer:
DynaPred: A structure and sequence based method for the prediction of MHC class I binding peptide sequences and conformations. ISMB (Supplement of Bioinformatics) 2006: 16-24 - 2005
- [j67]Niko Beerenwinkel, Jörg Rahnenführer, Rolf Kaiser, Daniel Hoffmann, Joachim Selbig, Thomas Lengauer:
Mtreemix: a software package for learning and using mixture models of mutagenetic trees. Bioinform. 21(9): 2106-2107 (2005) - [j66]Jörg Rahnenführer, Niko Beerenwinkel, Wolfgang A. Schulz, Christian Hartmann, Andreas von Deimling, Bernd Wullich, Thomas Lengauer:
Estimating cancer survival and clinical outcome based on genetic tumor progression scores. Bioinform. 21(10): 2438-2446 (2005) - [j65]Tobias Sing, Oliver Sander, Niko Beerenwinkel, Thomas Lengauer:
ROCR: visualizing classifier performance in R. Bioinform. 21(20): 3940-3941 (2005) - [j64]Niko Beerenwinkel, Tobias Sing, Thomas Lengauer, Jörg Rahnenführer, Kirsten Roomp, Igor Savenkov, Roman Fischer, Daniel Hoffmann, Joachim Selbig, Klaus Korn, Hauke Walter, Thomas Berg, Patrick Braun, Gerd Fätkenheuer, Mark Oette, Jürgen K. Rockstroh, Bernd Kupfer, Rolf Kaiser, Martin Däumer:
Computational methods for the design of effective therapies against drug resistant HIV strains. Bioinform. 21(21): 3943-3950 (2005) - [j63]Christoph Bock, Sabine Reither, Thomas Mikeska, Martina Paulsen, Jörn Walter, Thomas Lengauer:
BiQ Analyzer: visualization and quality control for DNA methylation data from bisulfite sequencing. Bioinform. 21(21): 4067-4068 (2005) - [j62]Andreas Hahn, Jörg Rahnenführer, Priti Talwar, Thomas Lengauer:
Confirmation of human protein interaction data by human expression data. BMC Bioinform. 6: 112 (2005) - [j61]Thomas Lengauer:
The DFG Priority Program "Informatics Methods for the Analysis and Interpretation of Large Genomic Datasets". it Inf. Technol. 47(4): 226-231 (2005) - [j60]Niko Beerenwinkel, Jörg Rahnenführer, Martin Däumer, Daniel Hoffmann, Rolf Kaiser, Joachim Selbig, Thomas Lengauer:
Learning Multiple Evolutionary Pathways from Cross-Sectional Data. J. Comput. Biol. 12(6): 584-598 (2005) - [j59]Christian Merkwirth, Thomas Lengauer:
Automatic Generation of Complementary Descriptors with Molecular Graph Networks. J. Chem. Inf. Model. 45(5): 1159-1168 (2005) - [j58]Iris Antes, Christian Merkwirth, Thomas Lengauer:
POEM: Parameter Optimization Using Ensemble Methods: Application to Target Specific Scoring Functions. J. Chem. Inf. Model. 45(5): 1291-1302 (2005) - [c64]Mario Albrecht, Carola Huthmacher, Silvio C. E. Tosatto, Thomas Lengauer:
Decomposing protein networks into domain-domain interactions. ECCB/JBI 2005: 221 - [c63]Tobias Sing, Niko Beerenwinkel, Thomas Lengauer, Valentina Svicher, Francesca Ceccherini-Silberstein, Carlo-Federico Perno:
Supervised and Unsupervised Approaches for Analyzing Covariation and Phenotypic Impact of HIV Drug Resistance Mutations. LWA 2005: 234-239 - [c62]Tobias Sing, Valentina Svicher, Niko Beerenwinkel, Francesca Ceccherini-Silberstein, Martin Däumer, Rolf Kaiser, Hauke Walter, Klaus Korn, Daniel Hoffmann, Mark Oette, Jürgen K. Rockstroh, Gerd Fätkenheuer, Carlo-Federico Perno, Thomas Lengauer:
Characterization of Novel HIV Drug Resistance Mutations Using Clustering, Multidimensional Scaling and SVM-Based Feature Ranking. PKDD 2005: 285-296 - 2004
- [j57]Torsten Crass, Iris Antes, Rico Basekow, Peer Bork, Christian Buning, Maik Christensen, Holger Claussen, Christian Ebeling, Peter Ernst, Valérie Gailus-Durner, Karl-Heinz Glatting, Rolf Gohla, Frank Gößling, Korbinian Grote, Karsten R. Heidtke, Alexander Herrmann, Sean O'Keeffe, O. Kießlich, Sven Kolibal, Jan O. Korbel, Thomas Lengauer, Ines Liebich, Mark van der Linden, Hannes Luz, Kathrin Meissner, Christian von Mering, Heinz-Theodor Mevissen, Hans-Werner Mewes, Holger Michael, Martin Mokrejs, Tobias Müller, Heike Pospisil, Matthias Rarey, Jens G. Reich, Ralf Schneider, Dietmar Schomburg, Steffen Schulze-Kremer, Knut Schwarzer, Ingolf Sommer, Stephan Springstubbe, Sándor Suhai, Gnanasekaran Thoppae, Martin Vingron, Jens Warfsmann, Thomas Werner, Daniel Wetzler, Edgar Wingender, Ralf Zimmer:
The Helmholtz Network for Bioinformatics: an integrative web portal for bioinformatics resources. Bioinform. 20(2): 268-270 (2004) - [j56]Ingolf Sommer, Jörg Rahnenführer, Francisco S. Domingues, Ulrik de Lichtenberg, Thomas Lengauer:
Predicting protein structure classes from function predictions. Bioinform. 20(5): 770-776 (2004) - [j55]Niklas von Öhsen, Ingolf Sommer, Ralf Zimmer, Thomas Lengauer:
Arby: automatic protein structure prediction using profile-profile alignment and confidence measures. Bioinform. 20(14): 2228-2235 (2004) - [j54]Christian Merkwirth, Harald Mauser, Tanja Schulz-Gasch, Olivier Roche, Martin Stahl, Thomas Lengauer:
Ensemble Methods for Classification in Cheminformatics. J. Chem. Inf. Model. 44(6): 1971-1978 (2004) - [c61]Niko Beerenwinkel, Jörg Rahnenführer, Martin Däumer, Daniel Hoffmann, Rolf Kaiser, Joachim Selbig, Thomas Lengauer:
Learning multiple evolutionary pathways from cross-sectional data. RECOMB 2004: 36-44 - [c60]Tobias Sing, Niko Beerenwinkel, Thomas Lengauer:
Learning Mixtures of Localized Rules by Maximizing the Area Under the ROC Curve. ROCAI 2004: 89-96 - 2003
- [j53]Mario Albrecht, Thomas Lengauer:
Pyranose Oxidase Identified as A Member of the GMC Oxidoreductase Family. Bioinform. 19(10): 1216-1220 (2003) - [j52]Mario Albrecht, Thomas Lengauer, Stefan Schreiber:
Disease-associated variants in PYPAF1 and NOD2 result in similar alterations of conserved sequence. Bioinform. 19(17): 2171-2175 (2003) - [j51]Alexander Zien, Juliane Fluck, Ralf Zimmer, Thomas Lengauer:
Microarrays: How Many Do You Need? J. Comput. Biol. 10(3/4): 653-667 (2003) - [j50]Marcus Peinado, Thomas Lengauer:
Parallel 'go with the winners' algorithms in distributed memory models. J. Parallel Distributed Comput. 63(9): 801-814 (2003) - [j49]Niko Beerenwinkel, Martin Däumer, Mark Oette, Klaus Korn, Daniel Hoffmann, Rolf Kaiser, Thomas Lengauer, Joachim Selbig, Hauke Walter:
Geno2pheno: estimating phenotypic drug resistance from HIV-1 genotypes. Nucleic Acids Res. 31(13): 3850-3855 (2003) - [c59]Thomas Lengauer:
Analyzing resistance phenomena in HIV with bioinformatics methods. ECCB 2003: 92 - [c58]Niko Beerenwinkel, Thomas Lengauer, Martin Däumer, Rolf Kaiser, Hauke Walter, Klaus Korn, Daniel Hoffmann, Joachim Selbig:
Methods for optimizing antiviral combination therapies. ISMB (Supplement of Bioinformatics) 2003: 16-25 - 2002
- [j48]Ingolf Sommer, Alexander Zien, Niklas von Öhsen, Ralf Zimmer, Thomas Lengauer:
Confidence measures for protein fold recognition. Bioinform. 18(6): 802-812 (2002) - [j47]Daniel Hanisch, Ralf Zimmer, Thomas Lengauer:
ProML - the Protein Markup Language for specification of protein sequences, structures and families. Silico Biol. 2(3): 313-324 (2002) - [j46]Mario Albrecht, Daniel Hanisch, Ralf Zimmer, Thomas Lengauer:
Improving fold recognition of protein threading by experimental distance constraints. Silico Biol. 2(3): 325-337 (2002) - [j45]Jan Freudenberg, Ralf Zimmer, Daniel Hanisch, Thomas Lengauer:
A hypergraph-based method for unification of existing protein structure- and sequence-families. Silico Biol. 2(3): 339-349 (2002) - [j44]Sally A. Hindle, Matthias Rarey, Christian Buning, Thomas Lengauer:
Flexible docking under pharmacophore type constraints. J. Comput. Aided Mol. Des. 16(2): 129-149 (2002) - [j43]Thomas Lengauer:
Preface: Special RECOMB 2001 Issue. J. Comput. Biol. 9(2): 147-148 (2002) - [j42]Niko Beerenwinkel, Barbara Schmidt, Hauke Walter, Rolf Kaiser, Thomas Lengauer, Daniel Hoffmann, Klaus Korn, Joachim Selbig:
Diversity and complexity of HIV-1 drug resistance: A bioinformatics approach to predicting phenotype from genotype. Proc. Natl. Acad. Sci. USA 99(12): 8271-8276 (2002) - [c57]Thomas Lengauer:
Editorial. ECCB 2002: 1 - [c56]Thomas Lengauer:
ECCB 2002 Organization. ECCB 2002: 2-3 - [c55]Daniel Hanisch, Alexander Zien, Ralf Zimmer, Thomas Lengauer:
Co-clustering of biological networks and gene expression data. ISMB 2002: 145-154 - [c54]Alexander Zien, Juliane Fluck, Ralf Zimmer, Thomas Lengauer:
Microarrays: how many do you need? RECOMB 2002: 321-330 - 2001
- [j41]Niko Beerenwinkel, Barbara Schmidt, Hauke Walter, Rolf Kaiser, Thomas Lengauer, Daniel Hoffmann, Klaus Korn, Joachim Selbig:
Geno2pheno: Interpreting Genotypic HIV Drug Resistance Tests. IEEE Intell. Syst. 16(6): 35-41 (2001) - [c53]Thomas Lengauer:
Computational Biology at the Beginning of the Post-genomic Era. Informatics 2001: 341-355 - [c52]Ingolf Sommer, Niklas von Öhsen, Alexander Zien, Ralf Zimmer, Thomas Lengauer:
Confidence Measures for Fold Recognition. German Conference on Bioinformatics 2001: 26-33 - [c51]Daniel Hanisch, Ralf Zimmer, Thomas Lengauer:
ProML - the Protein Markup Language for specification of protein sequences, structures and families. German Conference on Bioinformatics 2001: 58-67 - [c50]Mario Albrecht, Daniel Hanisch, Ralf Zimmer, Thomas Lengauer:
Improving Fold Recognition of Protein Threading by Experimental Distance Constraints. German Conference on Bioinformatics 2001: 68-77 - [c49]Jan Freudenberg, Ralf Zimmer, Daniel Hanisch, Thomas Lengauer:
A new Method for Unification of Existing Protein Structure- and Sequence-Families. German Conference on Bioinformatics 2001: 78-84 - [c48]Niko Beerenwinkel, Barbara Schmidt, Hauke Walter, Rolf Kaiser, Thomas Lengauer, Daniel Hoffmann, Klaus Korn, Joachim Selbig:
Identifying drug resistance-associated patterns in HIV genotypes. German Conference on Bioinformatics 2001: 126-130 - [c47]Alexander Zien, Thomas Aigner, Ralf Zimmer, Thomas Lengauer:
Centralization: a new method for the normalization of gene expression data. ISMB (Supplement of Bioinformatics) 2001: 323-331 - [e8]Thomas Lengauer:
Proceedings of the Fifth Annual International Conference on Computational Biology, RECOMB 2001, Montréal, Québec, Canada, April 22-25, 2001. ACM 2001, ISBN 1-58113-353-7 [contents] - 2000
- [j40]Thomas Lengauer, Ralf Zimmer:
Protein Structure Prediction Methods for Drug Design. Briefings Bioinform. 1(3): 275-288 (2000) - [j39]Alexander Zien, Gunnar Rätsch, Sebastian Mika, Bernhard Schölkopf, Thomas Lengauer, Klaus-Robert Müller:
Engineering support vector machine kernels that recognize translation initiation sites. Bioinform. 16(9): 799-807 (2000) - [j38]Robert Küffner, Ralf Zimmer, Thomas Lengauer:
Pathway analysis in metabolic databases via differential metabolic display (DMD). Bioinform. 16(9): 825-836 (2000) - [j37]Christian Lemmen, Thomas Lengauer:
Computational methods for the structural alignment of molecules. J. Comput. Aided Mol. Des. 14(3): 215-232 (2000) - [j36]Alexander Zien, Ralf Zimmer, Thomas Lengauer:
A Simple Iterative Approach to Parameter Optimization. J. Comput. Biol. 7(3-4): 483-501 (2000) - [j35]Thomas Lengauer, Martin Lügering:
Provably Good Global Routing of Integrated Circuits. SIAM J. Optim. 11(1): 1-30 (2000) - [c46]Thomas Lengauer:
Computational Biology - Algorithms and More. ESA 2000: 9-19 - [c45]Thomas Lengauer:
Bioinformatics Problems Along the Process Line from Genomic Data to New Drugs. German Conference on Bioinformatics 2000: 189 - [c44]Alexander Zien, Robert Küffner, Ralf Zimmer, Thomas Lengauer:
Analysis of Gene Expression Data with Pathway Scores. ISMB 2000: 407-417 - [c43]Alexander Zien, Ralf Zimmer, Thomas Lengauer:
A simple iterative approach to parameter optimization. RECOMB 2000: 318-327 - [e7]Philip E. Bourne, Michael Gribskov, Russ B. Altman, Nancy Jensen, Debra A. Hope, Thomas Lengauer, Julie C. Mitchell, Eric D. Scheeff, Chris Smith, Shawn Strande, Helge Weissig:
Proceedings of the Eighth International Conference on Intelligent Systems for Molecular Biology, August 19-23, 2000, La Jolla / San Diego, CA, USA. AAAI 2000, ISBN 1-57735-115-0 [contents]
1990 – 1999
- 1999
- [j34]Matthias Rarey, Bernd Kramer, Thomas Lengauer:
Docking of hydrophobic ligands with interaction-based matching algorithms. Bioinform. 15(3): 243-250 (1999) - [j33]Thomas Lengauer:
Editorial. The Seventh International Conference on Intelligent Systems for Molecular Biology (ISMB'99). Bioinform. 15(10): 775 (1999) - [j32]Joachim Selbig, Heinz-Theodor Mevissen, Thomas Lengauer:
Decision tree-based formation of consensus protein secondary structure prediction. Bioinform. 15(12): 1039-1046 (1999) - [c42]Alexander Zien, Gunnar Rätsch, Sebastian Mika, Bernhard Schölkopf, Christian Lemmen, Alexander J. Smola, Thomas Lengauer, Klaus-Robert Müller:
Engineering Support Vector Machine Kerneis That Recognize Translation Initialion Sites. German Conference on Bioinformatics 1999: 37-43 - [c41]Robert Küffner, Ralf Zimmer, Thomas Lengauer:
Pathway analysis in metabolic databases via differetial metabolic display (DMD). German Conference on Bioinformatics 1999: 141-147 - [c40]Christian Lemmen, Alexander Zien, Ralf Zimmer, Thomas Lengauer:
Application of Parameter Optimization to Molecular Comparison Problems. Pacific Symposium on Biocomputing 1999: 482-493 - [c39]Thomas Lengauer:
Invited Lecture: Discrete Optimization Methods for Packing Problems in Two and Three Dimensions - With Applications in the Textile and Car Manufacturing Industries. WG 1999: 27-28 - [e6]Thomas Lengauer, Reinhard Schneider, Peer Bork, Douglas L. Brutlag, Janice I. Glasgow, Hans-Werner Mewes, Ralf Zimmer:
Proceedings of the Seventh International Conference on Intelligent Systems for Molecular Biology, August 6-10, 1999, Heidelberg, Germany. AAAI 1999, ISBN 1-57735-083-9 [contents] - 1998
- [j31]Ralf Heckmann, Thomas Lengauer:
Computing closely matching upper and lower bounds on textile nesting problems. Eur. J. Oper. Res. 108(3): 473-489 (1998) - [j30]Christian Lemmen, Claus Hiller, Thomas Lengauer:
RigFit: A new approach to superimposing ligand molecules. J. Comput. Aided Mol. Des. 12(5): 491-502 (1998) - [c38]Matthias Rarey, Bernd Kramer, Thomas Lengauer:
Docking of hydrophobic ligands with interaction-based matching algorithms. German Conference on Bioinformatics 1998 - [c37]Marcus Peinado, Thomas Lengauer:
Random Generation of Embedded Graphs and an Extension to Dobrushin Uniqueness (Extended Abstract). STOC 1998: 176-185 - 1997
- [j29]Christian Lemmen, Thomas Lengauer:
Time-efficient flexible superposition of medium-sized molecules. J. Comput. Aided Mol. Des. 11(4): 357-368 (1997) - [j28]Matthias Rarey, Bernd Kramer, Thomas Lengauer:
Multiple automatic base selection: Protein-ligand docking based on incremental construction without manual intervention. J. Comput. Aided Mol. Des. 11(4): 369-384 (1997) - [c36]Christian Lemmen, Claus Hiller, Thomas Lengauer:
RigFit: a new approach to superimposing ligand molecules. German Conference on Bioinformatics 1997: 103-105 - [c35]Franz-Josef Brandenburg, Michael Jünger, Petra Mutzel, Thomas Lengauer:
Algorithmen zum automatischen Zeichnen von Graphen im Rahmen des DFG-Schwerpunkts Effiziente Algorithmen für diskrete Probleme und ihre Anwendungen. GI Jahrestagung 1997: 58-67 - [c34]Thomas Lengauer:
DFG-Schwerpunkt: Informatikmethoden zur Analyse und Interpretation großer genomischer Datenmengen. GI Jahrestagung 1997: 76-84 - [c33]Marcus Peinado, Thomas Lengauer:
Parallel 'Go with the Winners' Algorithms in the LogP Model. IPPS 1997: 656-664 - [c32]Ina Koch, Thomas Lengauer:
Detection of Distant Structural Similarities in a Set of Proteins Using a Fast Graph-Based Method. ISMB 1997: 167-178 - [c31]Marcus Peinado, Thomas Lengauer:
'Go with the winners' Generators with Applications to Molecular Modeling. RANDOM 1997: 135-149 - [c30]Ralf Zimmer, Thomas Lengauer:
Fast and numerically stable parametric alignment of biosequences. RECOMB 1997: 344-353 - [e5]Ralf Hofestädt, Thomas Lengauer, Markus Löffler, Dietmar Schomburg:
Bioinformatics, German Conference on Bioinformatics, Leipzig, Germany, September 30 - October 2, 1996, Selected Papers. Lecture Notes in Computer Science 1278, Springer 1997, ISBN 3-540-63370-7 [contents] - 1996
- [j27]Ralf Hofestädt, Markus Löffler, Thomas Lengauer:
Editorial: Informatik in den Biowissenschaften. Informationstechnik Tech. Inform. 38(5): 5-7 (1996) - [j26]Matthias Rarey, Stephan Wefing, Thomas Lengauer:
Placement of medium-sized molecular fragments into active sites of proteins. J. Comput. Aided Mol. Des. 10(1): 41-54 (1996) - [j25]Ina Koch, Thomas Lengauer, Egon Wanke:
An Algorithm for Finding Maximal Common Subtopologies in a Set of Protein Structures. J. Comput. Biol. 3(2): 289-306 (1996) - [c29]Ralf Heckmann, Thomas Lengauer:
Computing Upper and Lower Bounds on Textile Nesting Problems. ESA 1996: 392-405 - [c28]Christian Lemmen, Thomas Lengauer:
Time-Efficient Flexible Superposition of Medium-Sized Molecules and Molecular Fragments. German Conference on Bioinformatics 1996: 257-259 - 1995
- [j24]Ralf Heckmann, Thomas Lengauer:
A simulated annealing approach to the nesting problem in the textile manufacturing industry. Ann. Oper. Res. 57(1): 103-133 (1995) - [j23]Jörg Heistermann, Thomas Lengauer:
The nesting problem in the leather manufacturing industry. Ann. Oper. Res. 57(1): 147-173 (1995) - [c27]H. Schmidt, Dirk Theune, Ralf Thiele, Thomas Lengauer:
EMC-driven midway routing on PCBs. ED&TC 1995: 486-491 - [c26]Elof Frank, Thomas Lengauer:
APPlaUSE: Area and performance optimization in a unified placement and synthesis environment. ICCAD 1995: 662-667 - [c25]Matthias Rarey, Bernd Kramer, Thomas Lengauer:
Time-Efficient Docking of Flexible Ligands into Active Sites of Proteins. ISMB 1995: 300-308 - [c24]Ralf Thiele, Ralf Zimmer, Thomas Lengauer:
Recursive Dynamic Programming for Adaptive Sequence and Structure Alignment. ISMB 1995: 384-392 - [e4]Christopher J. Rawlings, Dominic A. Clark, Russ B. Altman, Lawrence Hunter, Thomas Lengauer, Shoshana J. Wodak:
Proceedings of the Third International Conference on Intelligent Systems for Molecular Biology, Cambridge, United Kingdom, July 16-19, 1995. AAAI 1995, ISBN 0-929280-83-0 [contents] - 1994
- [j22]Dirk Theune, Ralf Thiele, Werner John, Thomas Lengauer:
Robust methods for EMC-driven routing. IEEE Trans. Comput. Aided Des. Integr. Circuits Syst. 13(11): 1366-1378 (1994) - 1993
- [j21]Thomas Lengauer, Egon Wanke:
Efficient Decision Procedures for Graph Properties on Centext-Free Graph Languages. J. ACM 40(2): 368-393 (1993) - [j20]Ralf Hofestädt, Fritz Krückeberg, Thomas Lengauer:
1. Fachtagung "Informatik in den Biowissenschaften". Künstliche Intell. 7(3): 31 (1993) - [j19]Thomas Lengauer, Rolf Müller:
Robust and accurate hierarchical floorplanning with integrated global wiring. IEEE Trans. Comput. Aided Des. Integr. Circuits Syst. 12(6): 802-809 (1993) - [c23]Thomas Lengauer:
Informatik in den technischen Disziplinen. Perspektiven der Informatik 1993: 13-16 - [c22]Thomas Lengauer:
Informatik in den Naturwissenschaften. Perspektiven der Informatik 1993: 16-20 - [c21]Thomas Lengauer:
Algorithmic Research Problems in Molecular Bioinformatics. ISTCS 1993: 177-192 - [c20]Jörg Heistermann, Thomas Lengauer:
Efficient Automatic Part Nesting on Irregular and Inhomogeneous Surfaces. SODA 1993: 251-259 - [p2]Thomas Lengauer, Martin Lügering:
Integer Program formulations of Global Routing and Placement Problems. Algorithmic Aspects of VLSI Layout 1993: 167-197 - [e3]Ralf Hofestädt, Fritz Krückeberg, Thomas Lengauer:
Informatik in den Biowissenschaften, 1. Fachtagung der GI-FG 4.0.3 "Informatik in den Biowissenschaften", Bonn, 15./16. Februar 1993, Proceedings. Informatik Aktuell, Springer 1993, ISBN 3-540-56456-X [contents] - [e2]Thomas Lengauer:
Algorithms - ESA '93, First Annual European Symposium, Bad Honnef, Germany, September 30 - October 2, 1993, Proceedings. Lecture Notes in Computer Science 726, Springer 1993, ISBN 3-540-57273-2 [contents] - 1992
- [j18]Thomas Lengauer, Klaus W. Wagner:
The Correlation between the Complexities of the Nonhierarchical and Hierarchical Versions of Graph Problems. J. Comput. Syst. Sci. 44(1): 63-93 (1992) - [c19]Franz Höfting, Thomas Lengauer, Egon Wanke:
Processing of Hierarchically Defined Graphs and Graph Families. Data Structures and Efficient Algorithms 1992: 44-69 - [c18]Dirk Theune, Ralf Thiele, Thomas Lengauer, Anja Feldmann:
HERO: hierarchical EMC-constrained routing. ICCAD 1992: 468-472 - 1991
- [j17]Jörg Heistermann, Thomas Lengauer:
The efficient solution of integer programs for hierarchical global routing. IEEE Trans. Comput. Aided Des. Integr. Circuits Syst. 10(6): 748-753 (1991) - [c17]Frank Buijs, Thomas Lengauer:
Synthesis of multi-level logic with one symbolic input. EURO-DAC 1991: 60-64 - [c16]Thomas Lengauer, Dirk Theune:
Efficient Algorithms for Path Problems with Gernal Cost Citeria. ICALP 1991: 314-326 - [c15]Thomas Lengauer, Dirk Theune:
Unstructured Path Problems and the Making of Semirings (Preliminary Version). WADS 1991: 189-200 - 1990
- [b2]Thomas Lengauer:
Combinatorial algorithms for integrated circuit layout. Applicable theory in computer science, Teubner 1990, ISBN 978-0-471-92838-6, pp. I-XXVIII, 1-697 - [j16]Thomas Lengauer, Klaus W. Wagner:
The Binary Network Flow Problem is Logspace Complete for P. Theor. Comput. Sci. 75(3): 357-363 (1990) - [c14]Thomas Lengauer, Rolf Müller:
A Robust Framework for Hierarchical Floorplanning with Integrated Global Wiring. ICCAD 1990: 148-151 - [p1]Thomas Lengauer:
VLSI Theory. Handbook of Theoretical Computer Science, Volume A: Algorithms and Complexity (A) 1990: 835-868 - [e1]Christian Choffrut, Thomas Lengauer:
STACS 90, 7th Annual Symposium on Theoretical Aspects of Computer Science, Rouen, France, February 22-24, 1990, Proceedings. Lecture Notes in Computer Science 415, Springer 1990, ISBN 3-540-52282-4 [contents]
1980 – 1989
- 1989
- [j15]Thomas Lengauer:
Hierarchical planarity testing algorithms. J. ACM 36(3): 474-509 (1989) - 1988
- [j14]Thomas Lengauer, Egon Wanke:
Efficient processing of hierarchical graphs for engineering design. Bull. EATCS 35: 143-157 (1988) - [j13]Thomas Lengauer, Rolf Müller:
Linear arrangement problems on recursively partitioned graphs. ZOR Methods Model. Oper. Res. 32(3-4): 213-230 (1988) - [j12]Thomas Lengauer, Egon Wanke:
Efficient Solution of Connectivity Problems on Hierarchically Defined Graphs. SIAM J. Comput. 17(6): 1063-1080 (1988) - [c13]Thomas Lengauer, Egon Wanke:
Efficient Analysis of Graph Properties on Context-free Graph Languages (Extended Abstract). ICALP 1988: 379-393 - 1987
- [j11]Thomas Lengauer, Christian Wieners:
Efficient solutions of hierarchical systems of linear equations. Computing 39(2): 111-132 (1987) - [j10]Thomas Lengauer:
Efficient Algorithms for Finding Minimum Spanning Forests of Hierarchically Defined Graphs. J. Algorithms 8(2): 260-284 (1987) - [j9]Jürgen Doenhardt, Thomas Lengauer:
Algorithmic Aspects of One-Dimensional Layout Compaction. IEEE Trans. Comput. Aided Des. Integr. Circuits Syst. 6(5): 863-878 (1987) - [c12]Thomas Lengauer, Klaus W. Wagner:
The Correlation Between the Complexities of the Nonhierarchical and Hierarchical Versions of Graph Problems. STACS 1987: 100-113 - 1986
- [j8]Thomas Lengauer, Stefan Näher:
An analysis of ternary simulation as a tool for race detection in digital MOS circuits. Integr. 4(4): 309-330 (1986) - [c11]Rolf Müller, Thomas Lengauer:
Linear Algorithms For Two CMOS Layout Problems. Aegean Workshop on Computing 1986: 121-132 - [c10]Thomas Lengauer:
Exploiting Hierarchy in VLSI Design. Aegean Workshop on Computing 1986: 180-193 - [c9]Thomas Lengauer:
Hierarchische Darstellung geometrischer Objekte und ihre algorithmische Bedeutung. GI Jahrestagung (1) 1986: 456-469 - [c8]Thomas Lengauer:
Hierarchical Planary Testing Algorithms. ICALP 1986: 215-225 - [c7]Thomas Lengauer:
Efficient Algorithms for Finding Minimum Spanning Forests of Hierarchically Defined Graphs. STACS 1986: 153-170 - 1984
- [j7]Thomas Lengauer:
On the Solution of Inequality Systems Relevant to IC-Layout. J. Algorithms 5(3): 408-421 (1984) - [c6]Thomas Lengauer:
Algorithmische Spezifikation von symbolischen Layouts integrierter Schaltkreise. GI Jahrestagung (Fachgespräche) 1984: 5-16 - 1983
- [c5]Thomas Lengauer:
Efficient Algorithms for the Constraint Generation for Integrated Circuit Layout Compaction. WG 1983: 219-230 - 1982
- [j6]Thomas Lengauer:
Cube-Connected Cycles - Shuffle Exchange Graph - Das aktuelle Schlagwort. Inform. Spektrum 5(3): 192-194 (1982) - [j5]Thomas Lengauer, Robert Endre Tarjan:
Asymptotically tight bounds on time-space trade-offs in a pebble game. J. ACM 29(4): 1087-1130 (1982) - [c4]Thomas Lengauer:
The Complexity of Compacting Hierarchically Specified Layouts of Integrated Circuits (Preliminary Version). FOCS 1982: 358-368 - [c3]Thomas Lengauer:
On the Solution of Inequality Systems Relevant to IC-Layout. WG 1982: 151-164 - 1981
- [j4]Thomas Lengauer:
Black-White Pebbles and Graph Separation. Acta Informatica 16: 465-475 (1981) - 1980
- [j3]Thomas Lengauer, Robert Endre Tarjan:
The Space Complexity of Pebble Games on Trees. Inf. Process. Lett. 10(4/5): 184-188 (1980) - [j2]John R. Gilbert, Thomas Lengauer, Robert Endre Tarjan:
The Pebbling Problem is Complete in Polynomial Space. SIAM J. Comput. 9(3): 513-524 (1980)
1970 – 1979
- 1979
- [b1]Thomas Lengauer:
Upper and lower bounds on time-space tradeoffs in a pebble game. Stanford University, USA, 1979 - [j1]Thomas Lengauer, Robert Endre Tarjan:
A Fast Algorithm for Finding Dominators in a Flowgraph. ACM Trans. Program. Lang. Syst. 1(1): 121-141 (1979) - [c2]John R. Gilbert, Thomas Lengauer, Robert Endre Tarjan:
The Pebbling Problem is Complete in Polynomial Space. STOC 1979: 237-248 - [c1]Thomas Lengauer, Robert Endre Tarjan:
Upper and Lower Bounds on Time-Space Tradeoffs. STOC 1979: 262-277
Coauthor Index
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