Showing posts with label penicillin. Show all posts
Showing posts with label penicillin. Show all posts

Medicinal Amphibians


(Up from the depths crawls Penicillin Vol.3! Not only is it an early release, it's on sale. Go buy it, commune with it, absorb it into your being. This latest volume's almost twice as long as the last two and the unofficial theme is d r u g s, hallucination, and other altered states. The art is gorgeous. The material is system-agnostic and inspiring. It's incredible and you need it.)

Usually when you see a frog, toad, newt, or whatnot in fiction it's either of the "really generally poisonous" or the "gets you high" varieties. That's fairly realistic (because dosages are king in pharmacology), but I wanted more, so here's a suite of tables to generate medicinally useful amphibians of your very own! They're pretty self-explanatory, though you may need to look up some terms if you're not familiar with biology, ecology, and pharmacology. (Go wiki-walking! Learn! It's good for you!)


 While you're researching, here are some topics of interest when it comes to real-world amphibians (that can also be adapted for use in games):

 - Aposematism: Honest warning coloration on animals. It's often bright colors, but applies to any distinctive coloration or pattern that makes the creature conspicuous and says "go away" when you really should leave it alone.

 - Ecological indicators: Indicator species are plants and animals that are highly sensitive to changes in their habitat. When they're thriving, it's a good sign for the whole area. When they're declining, it's a sign that something's wrong and you need to sit up and take notice. Amphibians are often important indicator species because their highly permeable skin and water-reliant lifecycle makes them very vulnerable to pollution and disruption in their habitats.

 - The real-life toxins produced by amphibians in nature. They tend to fall into a similar band of nerve-disrupting chemicals and are absolutely fascinating.


 What's cool about these is that usually the amphibian doesn't produce the toxin itself. It gets it from its diet of other poisonous things (usually insects), either by sequestering the chemicals in their tissues or transforming them from a precursor chemical found in their prey to something even more toxic. If these amphibians are caught and kept, they'll gradually lose their toxicity because their diet in captivity doesn't contain the right chemicals. If they're raised in captivity and never eat a wild diet, they're not poisonous at all!

 This is why you have to adventure/quest for your medicinally valuable amphibians, they can't be farmed and still retain their potency. (Unless you create a free-range amphibian ranch, which sounds adorable.)



 Once you've finished reading about the delightful, mildly morbid world of poisonous amphibian toxicology, roll some dice!

 For some of the tables I've only given guidelines, it's up to you to fill in the details and make it work. Like the coloration table. If you roll "brilliant" it could be brilliant blue, red, orange, whatever so long as it's retina-searing and screams "do not eat!" Follow your heart and make something cool.

 (Remember! If you'd like to own these tables in a PDF or print format, along with all the excellent work from other contributors, go grab yourself a copy of Penicillin Vol.3.)

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Type (d6)
1) Frog
2) Toad
3) Newt
4) Salamander
5) Axolotl
6) Caecilian

Size (d6)
1) Tiny - Fits on fingertip
2) Small - Fits on finger
3) Medium - Fits on palm
4) Large - Fits on whole hand
5) Huge - Need two hands to lift
6) Massive - Larger than a cat

Skin Texture (d8)
1) Smooth
2) Smooth
3) Smooth
4) Rough
5) Bumpy/warty
6) Wrinkly
7) Spiked/horned
8) Dendritic/lacy

Coloration (d10)
1) Dull/earth tones
2) Subtle
3) Bright
4) Brilliant
5) Iridescent
6) Metallic
7) Translucent
8) Achromatic/grayscale
9) Roll again x2
10) Roll again x3

Pattern (d12)
1) Solid
2) Countershaded
3) Zones/patches of color
4) Spots
5) Flecks of color
6) Mottled/camouflaged
7) Stripes
8) Single stripe
9) Characteristic symbol/shape (like a black widow's hourglass)
10) Mobile/changing (chromatophores)
11) Roll again x2
12) Roll again x3

Body Shape (d6)
1) Average proportions
2) Slender/skeletal
3) Beefy/solid
4) Round/chunky
5) Stubby limbs
6) Flabby

Potency (1d8)
1) Weak - Need 10 to affect 1 adult human
2) Moderate - Need 1 to affect 1 adult human
3) Strong - Need 1 to affect 5 adult humans
4) Dangerous - Need 1 to affect 10 adult humans
5) Lethal - Need 1 to affect 100 adult humans
6) Increases with exposure - Starts weak and gets 1 degree stronger each time it's used after until it's lethal
7) Decreases with exposure - Starts lethal and gets 1 degree weaker each time it's used after until it's weak
8) Placebo

Habitat (d12)
1) River
2) Pond
3) Marsh/wetland
4) Bog
5) Vernal ponds
6) Stagnant water
7) Forest floor/understory
8) Trees
9) Jungle/rainforest
10) Epiphytes
11) Prairie/grassland
12) Desert

Administered By (d20)
(H is harmless to the creature, NL is not lethal but stressful, and F is fatal to it)
1) Skin contact (H)
2) Hold to an open wound (H)
3) Press to eyeball (H)
4) Lick it (H)
5) Soak it in oil and mix the oil into food (H)
6) Sit in a sweat lodge/sauna with them and breathe the steam (H)
7) Run on gums/under tongue (NL)
8) Just hold it in our mouth for a while, then spit it out (NL)
9) Wash it in alcohol and drink the tincture (NL)
10) Blotting paper (NL)
11) Eat it (1 whole, 2 raw, 3 dried, 4 powdered) (F)
12) Pills (F)
13) Mixed into tea or broth (F)
14) Snort it (F)
15) Smoke it (1 dried whole, 2 powdered, 3 mixed with resin, 4 shredded) (F)
16) Cut out the parotoid glands and squeeze into eyes (F)
17) Render down the skin, put drops of the liquid in boiling water and breathe the steam (F)
18) Render down the skin, apply liquid to a skewer/needle and stab the patient (F)
19) Roll again x2, the second method is less effective (1 lower potency)
20) Roll again x3, the second method is more effective (1 higher potency), the third method is lethal

Toxin Effect (d60)
1) Analgesic/numbing
2) Anesthetic
3) Sedative
4) Soporific/hypnotic
5) Serenic (decreased aggression)
6) Choleric (induces aggression)
7) Oneirogen (dream producing)
8) Narcotic
9) Hallucinogenic - Psychedelic
10) Hallucinogenic - Dissociative
11) Hallucinogenic - Deliriant
12) Stimulant
13) Depressant
14) Orexigenic (appetite stimulant)
15) Anoretic (appetite depressant)
16) Emetic
17) Laxative
18) Vasodilator
19) Vasoconstrictor
20) Hemorrhagic
21) Anticoagulant
22) Coagulant
23) Antipyretic (fever reducer)
24) Anti-inflammatory
25) Antihistamine
26) Diuretic
27) Contraceptive
28) Conceptive
29) Aphrodisiac
30) Anaphrodisiac (decreases libido)
31) Immunosuppressant
32) Vertigo (balance disruptor)
33) Irritant/inflammatory
34) Capsaicin analog (just pain/burning)
35) Menthol analog (chemical frostbite)
36) Blistering/caustic
37) Necrotic
38) Neurotoxic
39) Antibacterial
40) Antifungal
41) Antiviral
42) Antiparasitic
43) Antimiotic (disrupts cell division)
44) Paralytic
45) Hyperactive nerve conduction (seizure, paralysis, heart attack)
46) Hypoactive nerve conduction (peripheral nerve signaling blocked, paralysis, suffocate)
47) Antispasmodic
48) Muscle relaxant
49) Anxiogenic (increases anxiety)
50) Increased suggestibility
51) Induces insomnia
52) Eugeroic (promotes wakefulness)
53) Nootropic (enhances memory/thought)
54) Euphoriant
55) Entheogen (induces spiritual experiences)
56) Roll again x2
57) Roll again x3
58) Roll again x4
59) Roll again x5
60) Placebo

Plague Eater


Be advised: You can use this content right now, as-is, but you'll be missing out on the bizarre glory that is Penicillin vol 2

It has Plague Eater (a single facet of the glut of inspiring content) done right with gorgeous art and wild layout. It's a masterpiece and you need it. Grab a copy of the PDF, and a copy of volume 1. Happy Solstice!




It takes a moment- Jellied, attenuated seconds clawing through the haze of fever- To determine if the woman approaching your bedside is real. She is, and her eyes are kind.

Her movements are smooth and precise, observed detachedly through the heat shimmer of your illness. She presses a kiss to your forehead, grasps a fistful of hair with one gloved hand, places the other splayed over your nose and mouth, and pulls-

Deep in your chest something resists, digging barbs into your heart, your lungs, gouting sparkles of pain as she drags its coils out from your flesh. She brings her hand from your mouth to hers, trailing a mass of fine strands. Green-black and wetly iridescent, like beetle wings spun into thread. She gorges on it, drawing out yard after yard and slurping them up like noodles.

With each foot extracted, shards of lucidity rasp at the edges of your inflamed mind and congeal. Your breath comes easier. Your trembling chills subside. When she finishes her eyes glimmer with an edge of mania, a shadow of the fever she took from you. She takes a breath, coughs lightly into the back of her hand, then leans forward to kiss your brow again.

"Be well."




A Plague Eater heals the sick by drawing out illnesses and containing them encysted within their own bodies. The ritual required to consume disease is simple and can be learned by anyone so long as they find a teacher or detailed instructions.

Plague Eaters may consume as many different diseases or cases of the same disease as they like.

Consuming a disease takes as long as a short meal, completely heals the patient, and stores the disease within the Plague Eater. Stored diseases aren't contagious and the Plague Eater can't die from them, but a stat of their choice is reduced by 1 for each disease they hold. They also suffer an attenuated version of the symptoms (1/4 strength) that accumulates. Healing 2 people of different diseases will cause the Plague Eater to take 2 stat damage and feel a quarter of the symptoms of each disease. Healing 4 people of the same disease will cause 4 stat damage and the Plague Eater will suffer the full brunt of the disease's symptoms.

Plague Eaters can use their stored diseases two ways:

The can vaccinate others, granting immunity to any of their stored diseases. Every vaccination causes them to feel more symptoms. One quarter each time, after 3 vaccinations of the same disease they feel full symptoms.

They can inflict diseases on others. When a Plague Eater inflicts a disease it's expelled from their body. They lose access and immunity to it, regain a stat point, and all of the immunities they granted for that disease end. The disease becomes contagious again. They can only inflict a disease on creatures that can normally catch it.

The only way for a Plague Eater to recover their lost stat points or decrease the severity of their symptoms is by revoking immunities they've granted or purging themselves by inflicting diseases. They don't recuperate naturally from stored diseases and outside healing has no effect.

If a Plague Eater dies their stored diseases die with them, harmlessly contained in the body forever.

If a Plague Eater gets sick, actually contracting a disease instead of consuming it through their ritual, they will feel completely fine. All symptoms from their stored diseases will vanish and they'll begin to take 1 damage to their lowest stat each day. When that stat reaches 0 the Plague Eater disintegrates into an infectious dust, releasing all their stored diseases to be spread as an airborne vector. This can be averted by getting treatment or by inflicting all of their stored diseases on others.