Ahmed M. Hashad, Mohammad M. Abd-Alhaseeb, Xin Rui Lim, Natalia M. Mathieu, Osama F. Harraz. PIP 2 corrects an endothelial Piezo1 channelopathy. Proceedings of the National Academy of Sciences, 2025; http://dx.doi.org/10.1073/pnas.2522750122

Via Li Chen’s Mastodon.

Another more than $200 million in medical debt has been wiped out for Arizonans. And the recipients are going to know who to thank: Gov. Katie Hobbs.

Foreign Affairs Minister Anita Anand plans to visit the Greenland community of Nuuk to open a Canadian consulate there early next year.

Rabat (AFP) – Organisers at the Africa Cup of Nations in Morocco are allowing supporters in for free after kick-off in matches where stadiums are not full, a Confederation of African Football source told AFP.

Maiduguri (Nigeria) (AFP) – Nigeria police said Thursday that they suspected a suicide bomber was behind the blast that killed several worshippers in a mosque on Christmas eve in the country’s northeastern Borno state.

Of the total area that is used by humans (Agriculture, Urban and Built-up Land),

Dec. 24, 2025

*Rebecca Joynes is currently serving a six and a half year prison sentence*

An airplane has, for the first time, automatically landed itself after an in-flight emergency, according to the system’s manufacturer.

There are no roads through the Darién Gap. This vast impenetrable forest spans the width of the land bridge between South and Central America, but there is almost no way through it: hundreds have lost their lives trying to cross it on foot.

Israeli police arrested a Palestinian man dressed as Santa Claus during a raid on a Christmas party in Haifa, a civil rights monitor has said.

in the week before people were disappointed by a lack of snow… lucky us :)

Pentagon Paid Lockheed Martin $1.7B Despite Half Of F-35 Fleet Grounded By Poor Maintenance | Defense Express

I have posted about the L119/M119 before, but I will again because it is curiously largely ignored by the international community as a critical force multiplier in the Ukrainian military. Howitzers will be the bread and butter of ground armies long into the future no matter what armchair generals say about drones, missiles etc…

i.e. Almost all of Kupiansk has been liberated. A pocket of Russian forces is trapped.

The agreement allows for the potential supply of up to 500 RCH 155 self-propelled howitzers. Moreover, deliveries under this agreement may be made not only to the Bundeswehr but also to foreign customers. While 500 RCH 155s is an impressive number, the Bundeswehr probably does not need that many at present.

The codename for this release series is Tenacious Tomato. Today’s release is a beta/RC. You can find it here: https://rsync.libreboot.org/testing/26.01rc1/ Or you can find it on a mirror.

Exhibition of design flops should suit British sense of humour, says its founder, but also shows failure is a part of learning

https://www.youtube.com/watch?v=QfVcJO5Z2i4

According to the often-cited 3.5% rule, if 3.5% of a population protests against a regime, the regime will fail. Developed by political scientists Erica Chenoweth and Maria Stephan, who researched civil resistance campaigns from 1900 to 2006, the rule has seen renewed interest in leftist circles recently, especially with No Kings protests attracting historic numbers.

The lost tape of UNIX V4 was found, I gave it a spin and was amazed how fast you feel familiar using it.

transcription: can i come over and be strange and intense?

Christmas is often regarded as a time for goodwill, but one young UK couple’s act of kindness 50 years ago changed their lives forever.

Artillery units of Ukraine’s National Guard have conducted training exercises using a modernized BM-21 “Grad” multiple launch rocket system fitted with a new chassis and digital fire-control systems, according to the National Guard’s Separate Artillery Brigade on December 25.

ALGIERS, Algeria – Legislators in Algeria voted to declare France’s colonization of the North African country a crime, approving a law that calls for restitution of property taken by France during its 130-year rule, among other demands seeking to redress historical wrongs.

Happy Holidays

NEW YORK (AP) — Days after Ghislaine Maxwell asked a judge to immediately free her from a 20-year prison sentence, the public release of grand jury transcripts from her sex trafficking case returned the spotlight to victims whose allegations helped land her behind bars.

This latest update focuses on expanding the player’s offensive capabilities and significantly improving the overall atmosphere through a complete audio rework.

Archived version