I can repro like this. Probably device dependent. MacOS Chrome. My screen as 2 DPI.

1. Make sure your pixel size setting is set to 1.
2. Put a rectangle on the screen, eg:

shape().out()

3. Make sure it's visible and in the middle of the screen.
4. Change the pixel size setting to 2.

Expected: Rectangle is still within the middle of the screen.
Actual: Rectangle is not visible.

Interestingly, this works fine:

shape().scrollX(0).out()

Will investigate this further!