Summary

Request to add the METPO (Microbial Ecophysiological Trait and Phenotype Ontology) prefix to the Biolink Model prefixes section.

Prefix Definition

METPO: 'https://w3id.org/metpo/'

Justification

METPO provides ontology terms for microbial phenotypes and growth characteristics that are essential for knowledge graph representations of microbe-medium relationships. Key terms include:

• METPO:1004005 - growth medium (class)
• METPO:2000517 - grows in (object property, domain: microbe, range: growth medium)
• METPO:2000518 - does not grow in (object property)

These terms have defined domains and ranges that complement Biolink's representation of organisms and chemical entities.

Use Cases

• Representing strain-medium growth relationships in knowledge graphs (e.g., "Methylobacterium extorquens grows in MP medium")
• Integrating data from culture collections (BacDive, DSMZ, ATCC)
• KGX-based ETL pipelines for microbial knowledge graphs

Related Resources

• METPO repository: https://github.com/berkeleybop/metpo
• w3id.org namespace: https://w3id.org/metpo/
• Related project: cmm-ai-automation (Critical Mineral Metabolism AI)

Notes

METPO is developed at LBNL/Berkeley BOP and follows OBO Foundry principles. The ontology is hosted at w3id.org rather than purl.obolibrary.org.

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