Releases: brentp/vcfanno
fix for QUAL of 256
QUAL of 256 was previously set to ".".
Thanks to @ToonRosseel for the fix.
v0.3.6
fix regression from 0.3.4
This fixes a major bug in v0.3.4 (#150). Please update.
Full Changelog: v0.3.4...v0.3.5
v0.3.4
This release fixes and issue where the FORMAT column was added to the VCF header when no samples were present.
Full Changelog: v0.3.3...v0.3.4
v0.3.3
This contains minor usability fixes.
- 0314e53 - add vcfanno version to header (#140)
- c4c0ae9 - update travis
- 49ef500 - non-zero exit when no args are given
- 6e5a12a - fix help which still mentioned js.
- 9f857a9 - handle missing value in postannotation. closes #116
- 1d140d4 - Misleading Flatten error message (#119)
- 8ffa89c - fix example table format of markdown (#115)
general fixes and by_alt
this release has minor fixes to by_alt and other bugs:
- 8c692e2 - handle by_alt + float correctly (#113) (12 days ago)
- deeeee3 - Fix always falling back to non-bgzip reader (#109) (8 weeks ago)
- 54bcc00 - add go 1.11 (5 months ago)
- cc8048d - add release target to makefile (5 months ago)
- 5683246 - Add Makefile (#103) (5 months ago)
- 16701a1 - closes #99 (6 months ago)
fix for empty description
v0.3.1
- allow empty description in VCF header (sigven/pcgr#49)
minor updates
csi support
this release adds support for CSI. this can greatly speed up dense files like CADD and even gnomAD or ExAC.
to use, simply index your file with tabix as, e.g.:
tabix -m 12 --csi $file
and vcfanno will prefer the .csi index over the .tbi.
refer to the performance page for how to optimize.
in brief, setting
export IRELATE_MAX_GAP=1000
seems to give good results. Please experiment and let me know what works for you. I can get ~60% speed improvement using csi'd ExAC to annotate clinvar with the above changes.