Thanks for developing the application! GPN-MSA seems to be a great approach for predicting variant effects, especially for variants outside protein coding regions. I have a quick question about its application on non-human organisms: based on my understanding of the process, if I'd like to build a VEP for a non-human organism (our target organism), I need to use the MSA data set and re-train a model for the target organism, then run the "VEP" process on that model. Is this the correct way to do it?
Thanks for developing the application! GPN-MSA seems to be a great approach for predicting variant effects, especially for variants outside protein coding regions. I have a quick question about its application on non-human organisms: based on my understanding of the process, if I'd like to build a VEP for a non-human organism (our target organism), I need to use the MSA data set and re-train a model for the target organism, then run the "VEP" process on that model. Is this the correct way to do it?