When doctors detect elevated levels of SerpinB3 in a blood test, it can signal that something is seriously wrong, from hard-to-treat cancers to severe inflammatory conditions.
Nov 9, 2025
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A Penn-led team has revealed how hydralazine, one of the world's oldest blood pressure drugs and a mainstay treatment for preeclampsia, works at the molecular level. In doing so, they made a surprising discovery—it can ...
Nov 16, 2025
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Pancreatic cancer is notoriously hard to treat and often resists the most advanced immunotherapies. Northwestern Medicine scientists have uncovered a novel explanation for that resistance: Pancreatic tumors use a sugar-based ...
Nov 3, 2025
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Pancreatic cancer is one of the deadliest types of tumors. A team at the Technical University of Munich (TUM) reports that pancreatic tumors exploit the body's nervous system by forming so-called pseudosynapses.
Nov 11, 2025
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Pinned between the stomach and spine, the pancreas supervises both digestion and blood sugar in the body. It's also the site of an aggressive cancer called pancreatic ductal adenocarcinoma, or PDAC.
Nov 13, 2025
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The emergence of cancer drug resistance remains one of the most pressing problems in cancer care and there is a critical need to devise approaches to mitigate it. However, the molecular mechanisms driving treatment resistance ...
Nov 19, 2025
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Pancreatic cancer is among the deadliest forms of cancer, with most patients diagnosed after the disease has already spread throughout the body. The five-year survival rate for metastatic cases hovers around 2–3%, and median ...
Nov 25, 2025
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Immunotherapy, which harnesses our body's own immune system to fight cancer, has revolutionized modern oncology. Yet despite its success with several cancers, many patients still fail to respond to therapy or experience relapse ...
Nov 19, 2025
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A new study has discovered a molecular signal that tumors exploit to exhaust the T cells meant to destroy them—and how silencing that signal could revive the body's immunity.
Nov 17, 2025
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A new radioimmunotherapy approach has the potential to cure human epidermal growth factor receptor 2 (HER2)-positive breast cancer, according to new research published in the November issue of The Journal of Nuclear Medicine. ...
Nov 8, 2025
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