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Drug Study

Azithromycin is a macrolide antibiotic used to treat bacterial infections such as pneumonia, sinusitis, and gonorrhea. It works by binding to the bacterial ribosome to inhibit protein synthesis. Common side effects include headache, nausea, vomiting, and diarrhea. Nurses should monitor patients for signs of pseudomembranous colitis and interact with warfarin. Patients should minimize sun exposure and follow directions on timing of antacids while taking this medication.

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97 views2 pages

Drug Study

Azithromycin is a macrolide antibiotic used to treat bacterial infections such as pneumonia, sinusitis, and gonorrhea. It works by binding to the bacterial ribosome to inhibit protein synthesis. Common side effects include headache, nausea, vomiting, and diarrhea. Nurses should monitor patients for signs of pseudomembranous colitis and interact with warfarin. Patients should minimize sun exposure and follow directions on timing of antacids while taking this medication.

Uploaded by

Aubrey Unique Evangelista
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as DOCX, PDF, TXT or read online on Scribd
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AZITHROMYCIN

Stephen Josh V. Lim BSN 3A


Generic Name AZITHROMYCIN

Brand Name Zithromax, Zmax

Classification ANTIINFECTIVE; MACROLIDE ANTIBIOTIC


General Action A macrolide antibiotic that reversibly binds to the 50S ribosomal subunit of
susceptible organisms and consequently inhibits protein synthesis.
Dose and Route Bacterial Infections
Adult: PO 500 mg on day 1, then 250 mg q24h for 4 more d IV 500 mg
q.d. for at least 2 d, administer 1 mg/mL over 3 h or 2 mg/mL over 1 h
Child: PO 6 mo, 10 mg/kg on day 1, then 5 mg/kg for 4 more d (max:
250 mg/d)

Acute Bacterial Sinusitis


Adult: PO 500 mg once daily x 3 d. Zmax: single one-time dose of 2 g.
Child: PO 6 mo, 10 mg/kg once daily x 3 d

Otitis Media
Child: PO >6 mo, 30 mg/kg as a single dose or 10 mg/kg once daily (not to
exceed 500 mg/d) for 3 d or 10 mg/kg as a single dose on day 1 followed
by 5 mg/kg/d on days 2–5

Gonorrhea
Adult: PO 2 g as a single dose

Chancroid
Adult: PO 1 g as a single dose
Child: PO 20 mg/kg as single dose (max: 1 g)
Indications or Pneumonia, lower respiratory tract infections, pharyngitis/tonsillitis,
Purposes gonorrhea, nongonococcal urethritis, skin and skin structure infections due
to susceptible organisms, otitis media, Mycobacterium avium–
intracellulare complex infections, acute bacterial sinusitis. Zmax: acute
bacterial sinusitis and community acquired pneumonia.
Side effects CNS: Headache, dizziness.
GI: Nausea, vomiting, diarrhea, abdominal pain; hepatotoxicity, mild
elevations in liver function tests.
Contraindications Hypersensitivity to azithromycin, erythromycin, or any of the macrolide
antibiotics.
Nursing Assessment & Drug Effects
Responsibilities
 Monitor for and report loose stools or diarrhea, since
pseudomembranous colitis (see Appendix F) must be ruled out.
 Monitor PT and INR closely with concurrent warfarin use.

Patient & Family Education

 Direct sunlight (UV) exposure should be minimized during therapy


with drug.
 Take aluminum or magnesium antacids 2 h before or after drug.
 Report onset of loose stools or diarrhea.
 Do not breast feed while taking this drug without consulting
physician.

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