www.PDHcenter.com PDH Course M143 www.PDHonline.
org
Unidirectional Flow System Designs
1) Single Pass System: Filtered air enters the room, exits through the louvers and is not re-
circulated. The system is ideal for 100% makeup air or when ambient temperatures are
favorable and acceptable.
2) Re-circulated System: Filtered air enters the room, exits through plenum walls and is re-
circulated through a sealed plenum using motorized fan modules with HEPA filters. This is
the most popular design.
3) Ducted Plenum System: Filtered air enters the room, exits through plenum walls and is re-
circulated through air ducts directly to the HEPA filters.
(Refer to the figures under part IV)
3
ROOM PRESSURIZATION
A clean room facility may consist of multiple rooms with different requirements for cleanliness.
Rooms in a clean facility should be maintained at static pressures higher than atmospheric to
prevent infiltration by wind. Positive differential pressures should be maintained between the
rooms to ensure airflows from the cleanest space to the least clean space. The only exception to
using a positive differential pressure is when dealing with specific hazardous materials where the
statutory health & safety agencies require the room to be at a negative pressure.
Ventilation Air
Ventilation air volumes are dictated by the quantity of air required to maintain indoor air quality,
makeup for exhaust and for building pressurization. This provides assurance that carbon dioxide
and oxygen remain in balance and that formaldehyde and other vapors given off by building
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