DAVAO DOCTORS COLLEGE CRITERIA:

Content and organization

General Malvar St., Davao 40% Analysis 40%
Neatness and promptness 10%
City Nursing Program
Reference 10%
TOTAL 100%
DRUG STUDY

Name of Patient: Date of Admission: Room: Age: Sex:

Civil Status: Attending Physician:
DRUG NAME CLASSIFICATION / INDICATIONS CONTRAINDICATIONS ADVERSE EFFECTS NURSING
MECHANISM OF ACTION RESPONSIBILITY
BRAND NAME: CLASSIFICATION: Betamethasone Contraindicated in GU (Genitourinary): Conduct a thorough
Diprolene Corticosteroids dipropionate is indicated patients with a history of  Glucosuria assessment of the patient's
for the relief of: sensitivity to skin condition, including
GENERIC NAME: MECHANISM OF ACTION: betamethasone Metabolic: the type and location of
betamethasone Topical corticosteroids, Inflammation and pruritus dipropionate, other  Hyperglycemia the affected area.
dipropionate such as betamethasone from corticosteroid- corticosteroids, or any of
dipropionate, are the components in these Skin:
responsive dermatoses. Administer cautiously to
preparations.  burning, pruritus,
DOSAGES AND effective in the treatment pregnant patients; topical
FREQUENCIES: of corticosteroid- Mild to moderate plaque irritation, dryness, corticosteroids have
Don’t use it as
500 mcg/ g once or twice responsive dermatoses psoriasis. erythema, caused teratogenic effects
monotherapy in primary
daily primarily because of their folliculitis, striae, and can be absorbed from
bacterial infections
anti-inflammatory, (impetigo, paronychia, acneiform systemic sites.
antipruritic, and cellulitis), rosacea, perioral eruptions, perioral
vasoconstrictive actions. dermatitis, or acne. dermatitis, Assess patient
hypopigmentation, hypersensitivity to
Use in pregnancy only if hypertrichosis, betamethasone
the potential benefit allergic contact dipropionate or any of its
justifies the potential risk dermatitis, components.
to the fetus. Use secondary infection,
cautiously in patients maceration, Educate the patient on the
breastfeeding. atrophy, miliaria proper application
with occlusive
technique, the need for a
dressings,
thin, even layer, and the
application-site
importance of washing
pain.
 hands after application.
Others:
 HPA axis Ensure the patient
suppression understands the prescribed
 Cushing syndrome dosage, frequency, and
duration of betamethasone
dipropionate use.

Instruct the patient to

clean and dry the affected
area before applying the
medication to enhance its
absorption.

Advise the patient to use

gloves or a clean applicator
to avoid contamination and
prevent potential side
effects.

Emphasize the importance

of avoiding contact with
the eyes and mucous
membranes when applying
the medication.

Instruct the patient to

watch for signs of skin
thinning, redness, or
irritation and report these
to the healthcare provider.

Educate the patient about

the need to taper off the
medication as directed by
the healthcare provider to
prevent rebound
symptoms.

Ensure that the patient

follows the recommended
application schedule and
does not use the
medication beyond the
prescribed duration.

Accurately document the

patient's response to
treatment, any adverse
effects, and the progress of
the skin condition.

Collaborate with the

healthcare team, including
dermatologists, to adjust
the treatment plan if
necessary and monitor the
patient's overall well-being.

Teach how to apply the

drug.

Emphasize that the drug is

for external use only.

Tell the patient to wash

hands after application.

Tell the patient to stop the

drug and report signs of
systematic absorption, skin
irritation or ulceration,
hypersensitivity, visual
changes, or infection.
 Instruct not to use
occlusive dressings.

Discuss personal hygiene

measures to reduce the
chance of infection.

Document all aspects of

the patient’s treatment
(time, route, dosage,
patient’s response, any
side/adverse effects.
REFERENCES:
Comerford, K. C., &
Durkin, M. T. (2021).
Nursing 2021 drug
handbook. 41st edition.
Philadelphia, Wolters
Kluwer.

StackPath. (n.d.-b).
https://www.mims.com/p
hilippines/drug/info/diprol
ene?type=full

DRUG NAME CLASSIFICATION / INDICATIONS CONTRAINDICATIONS ADVERSE EFFECTS NURSING

MECHANISM OF ACTION RESPONSIBILITY
BRAND NAME: CLASSIFICATION: Dinoprostone is indicated Contraindicated in Significant: Monitor fetal heart rate,
Primigyn Oxytocics, prostaglandins to ripen an unfavorable patients with acute or Rarely, disseminated uterine activity,
cervix at or near term in history of pelvic intravascular coagulation progression of cervical
GENERIC NAME: MECHANISM OF ACTION: women who are pregnant. inflammatory disease, (DIC). dilation and effacement
dinoprostone Produces contractions vaginal infections or (gel, insert); confirmation
similar to those occurring cervicitis, placenta previa  shock. of fetal death (supp).
during labor at term by or unexplained vaginal
DOSAGES AND
bleeding, history of major
FREQUENCIES: stimulating the CV (Cardiovascular): Monitor signs of allergic
uterine surgery or
0.5 mg intravaginal for myometrium.  HTN reactions and anaphylaxis,
cesarean section,
every 6 hours cephalopelvic including pulmonary
disproportion, fetal GI (Gastrointestinal): symptoms (tightness in the
malpresentation, fetal  Diarrhea throat and chest,
distress, grand multipara,  Nausea wheezing, cough, dyspnea)
history of traumatic  Vomiting or skin reactions (rash,
delivery, ruptured pruritus, urticaria). Notify
membranes. Active GU (Genitourinary): the physician or nursing
cardiac, pulmonary, renal,  Uterine hypertonus staff immediately if these
or hepatic disease.  Uterine rupture reactions occur.
 Abruption placenta
 Pulmonary amniotic Be alert for signs of uterine
fluid embolism rupture. Signs include
 Rapid cervical
increased bleeding, sudden
dilatation
abdominal pain, and
 Vaginal warmth
changes in fetal heart rate.
 Irritation and pain.
Notify the physician or
nursing staff immediately if
Musculoskeletal:
these signs occur.
 Back pain

Respiratory: Assess blood pressure (BP)

 Asthma and compare it to normal
 Bronchospasm values. Report changes in
BP, either a problematic
Skin: decrease in BP
 Rash (hypotension resulting in
syncope) or a sustained
Immunologic: increase in BP
 Anaphylactoid (hypertension).
reactions including
Monitor the patient's
Others: hydration status and
 Fever encourage fluid intake as
needed.
Potentially Fatal:
 Cardiac arrest Assess and provide
appropriate nutrition to
maintain the patient's
energy levels.

Provide pain relief

strategies and comfort
measures, such as
positioning and relaxation
techniques.

Offer pain medications as

prescribed, if necessary.

Ensure that the patient is

aware of the potential risks
and complications
associated with the drug
administered.

Be prepared for any

potential emergencies,
such as uterine
hyperstimulation or uterine
rupture.

Have uterotonics and

tocolytics readily available
for use as directed by the
healthcare provider.

Accurately document the

patient's response to the
drug, including cervical
changes and contractions.

Record any side effects,

vital signs, and fetal
monitoring results.
 Communicate with the
healthcare team about the
patient's progress and any
concerns.

Continue to monitor the

patient and fetus after
administrating to assess
progress.

Assist with the transition to

active labor or any further
interventions as directed.
Offer post-procedure care
and support, including pain
management, comfort
measures, and
encouragement.

Document all aspects of

the patient’s treatment
(time, route, dosage,
patient’s response, any
side/adverse effects.
REFERENCE:
Dinoprostone. (n.d.).
McGraw Hill Medical.
https://fadavispt.mhmedic
al.com/content.aspx?
bookid=1873§ionid=13900
8588

DRUG NAME CLASSIFICATION / INDICATIONS CONTRAINDICATIONS ADVERSE EFFECTS NURSING

MECHANISM OF ACTION RESPONSIBILITY
BRAND NAME: CLASSIFICATION: Evening primrose is Precautions: SIDE EFFECTS Assess the patient's
Everprim Herbal Medicine, food indicated for atopic Pregnancy CNS (Central nervous medical history and
supplement capsule dermatitis (a type of system): current condition to
GENERIC NAME: eczema), rheumatoid Breastfeeding  Headache determine the
evening primrose MECHANISM OF ACTION: arthritis, premenstrual appropriateness of
Evening primrose, syndrome (PMS), breast Bleeding disorders GI (Gastrointestinal): therapy.
DOSAGES AND containing gamma- pain, menopause  Upset
FREQUENCIES: linolenic acid (GLA), symptoms, and other Allergies  Nausea Assess vital signs based on
2-6 g PO daily for 3-12 exerts its mechanism of conditions. status for baseline data.
action by converting GLA Epilepsy Surgery Skin:
months
into anti-inflammatory Indicated to prevent  Rash Verify the healthcare
For Breast Pain: prostaglandins, gestational hypertension provider's prescription and
3-4g PO daily particularly PGE1, which (preeclampsia), shorten Immune System: dosage instructions.
can regulate labor, and prevent late  Immunosuppression
inflammation, hormonal deliveries. with long-term use. Educate the patient on the
balance, and skin health. purpose of Evening
Used as a source of ADVERSE EFFECTS Primrose Oil and its
essential fatty acid. CNS (Central nervous potential benefits and
system): risks.
 Headache
 Seizure Discuss any known
allergies to components of
GI (Gastrointestinal):
Evening Primrose Oil, such
 Diarrhea
as GLA, with the patient.
 Fullness
 Nausea
 Abdominal pain Explain the importance of
adhering to the prescribed
GU (Genitourinary): dosing regimen for optimal
 therapeutic effect.

Hematologic: Guide how to take Evening

 Increase bleeding Primrose Oil with or
without food, as directed.
Respiratory:
 Difficulty breathing Encourage the patient to
report any unusual or
Skin: severe side effects
 Rash promptly.
 Skin irritation
Observe for nausea or
vomiting.

Monitor and document

the patient's response to
Evening Primrose Oil
therapy.

Increase oral intake if soft

stools are noted.

Evaluate any changes in

the patient's medical
condition and report to
the healthcare provider.

Assess for potential

allergic reactions,
especially if the patient
has allergies to nuts or
seeds.

Instruct the patient on the

appropriate disposal of
unused or expired
medication.

Ensure that the patient

understands the
significance of not
exceeding the prescribed
dosage.

Monitor the patient for

any drug interactions or
contraindications with
other medications.
 Collaborate with the
healthcare team to adjust
the Evening Primrose Oil
regimen as needed.

Provide emotional support

and address any concerns
or anxieties the patient
may have about the
medication.

Discuss the possibility of

any adverse effects
associated with Evening
Primrose Oil and its
management.

During follow-up visits,

assess and evaluate the
patient's progress and
response to Evening
Primrose Oil therapy,
making necessary
adjustments as indicated.

Document all aspects of

the patient’s treatment
(time, route, dosage,
patient’s response, any
side/adverse effects.
REFERENCE:
EVENING PRIMROSE OIL:
Overview, uses, side
effects, precautions,
interactions, dosing, and
reviews. (n.d.).
https://www.webmd.com/
 vitamins/ai/ingredientmon
o-1006/evening-primrose-
oil

A Drug Study On Evening

Primrose Oil.docx. (n.d.).
Scribd.
https://www.scribd.com/d
ocument/453681184/A-
Drug-Study-On-Evening-
Primrose-Oil-docx

DRUG NAME CLASSIFICATION / INDICATIONS CONTRAINDICATIONS ADVERSE EFFECTS NURSING

MECHANISM OF ACTION RESPONSIBILITY
BRAND NAME: CLASSIFICATION: These actions may help Contraindicated in SIDE EFFECTS Verify the medication
Vasodilan Pharmacologic class: treat the symptoms of patients with USP and Rare: order: Ensure that the
Peripheral Vasodilator conditions such as: should not be given  Chest pain prescription for isoxsuprine
GENERIC NAME: immediately postpartum  Dizziness or faintness hydrochloride is accurate
isoxsuprine hydrochloride MECHANISM OF ACTION: Cerebral vascular or in the presence of (more common for and up-to-date.
Isoxsuprine insufficiency (poor blood arterial bleeding.
injection)
DOSAGES and hydrochloride, a β- flow to the brain)  Fast heartbeat (more Review the patient's
Common contraindications
FREQUENCIES: agonist, increases muscle common for medical history: Assess the
for isoxsuprine
10mg – 20mg per tablet blood flow by directly Arteriosclerosis (hardening hydrochloride may injection) patient's medical history,
Adult: 3 to 4 times daily relaxing the vascular of the arteries)  Shortness of breath including allergies, prior
include:
(Oral) smooth muscle.  Skin rash adverse reactions to
Raynaud’s phenomenon, Hypersensitivity: medications, and any
and other conditions Individuals who have a Less common: contraindications.
involving poor blood flow known hypersensitivity or  Nausea or vomiting
in the veins and arteries. allergy to isoxsuprine (more common for Educate the patient:
hydrochloride or related injection) Provide the patient with
Prevention of Preterm drugs should not use it. information about the
Labor: Isoxsuprine may be ADVERSE EFFECTS medication, its purpose,
prescribed to delay or Active bleeding: potential side effects, and
CNS (Central nervous
prevent preterm labor by Isoxsuprine hydrochloride how to take it as directed.
system):
may increase the risk of
relaxing the uterine  Trembling
bleeding, so it should not
muscles. This can be  Nervousness Prepare the medication:
be used in patients with
beneficial in cases where active bleeding disorders.  Weakness Follow proper procedures
preterm birth is a  Dizziness for preparing isoxsuprine
significant concern. Recent heart attack: hydrochloride, such as
It is generally not CV (Cardiovascular): checking the medication
recommended for use in  Palpitation label, expiration date, and
patients who have had a  Tachycardia dosage.
recent heart attack.  Chest pain
 Hypotension Administer the medication:
Pregnancy:  Flushing Administer the drug via the
While isoxsuprine
hydrochloride is prescribed route, which
GI (Gastrointestinal): may include oral,
sometimes used to  Abdominal distress intravenous, or other
manage preterm labor, its  Nausea
use during pregnancy routes as ordered.
 Vomiting
should be carefully  Intestinal distention
considered. The decision Monitor vital signs:
to use it during pregnancy Regularly assess the
Skin:
is typically based on a risk- patient's blood pressure,
benefit assessment and
 Severe rash
heart rate, and respiratory
should be made by a rate, especially if the
healthcare provider. The medication is given
drug is not contraindicated intravenously.
in pregnancy when its
potential benefits
Assess for
outweigh the risks.
contraindications: Ensure
the patient does not have
contraindications to
isoxsuprine hydrochloride
use and promptly report
any concerns to the
healthcare provider.

Monitor for side effects:

Watch for side effects such
as dizziness, headache,
nausea, or palpitations and
report them to the
healthcare provider.
Evaluate therapeutic
response: Monitor the
patient's condition to
assess whether the
medication is effectively
managing their symptoms
or condition.

Provide pain relief:

Administer the medication
as needed to alleviate pain
or discomfort in patients
with peripheral vascular
disease.

Monitor for signs of

preterm labor: For patients
receiving isoxsuprine to
prevent or manage
preterm labor, closely
monitor uterine
contractions and fetal well-
being.

Document administration:
Maintain accurate and
complete records of
medication administration,
including the date, time,
dosage, and route.

Ensure proper dosage

calculations: Calculate the
correct dose based on the
patient's weight and other
relevant factors.
Check for drug interactions:
Be vigilant for potential
drug interactions with
other medications the
patient is taking.

Assess for allergies:

Confirm that the patient is
not allergic to isoxsuprine
hydrochloride or any of its
components.

Promote adherence:
Encourage patients to take
the medication as
prescribed and address any
concerns or questions they
may have.

Monitor fluid intake: For

patients receiving
intravenous isoxsuprine,
ensure they are adequately
hydrated, as dehydration
can increase the risk of side
effects.

Observe for changes in skin

color and temperature:
Patients with peripheral
vascular disease may
experience changes in skin
color or temperature, so
monitor for these signs.

Educate on side effect

management: Teach
 patients how to manage
and report common side
effects and when to seek
medical attention for
severe reactions.

Communicate with the

healthcare team: Maintain
open and clear
communication with
physicians and other
healthcare providers
regarding the patient's
response to isoxsuprine
and any concerns or
changes in the patient's
condition.

Document all aspects of

the patient’s treatment
(time, route, dosage,
patient’s response, any
side/adverse effects.
REFERENCE:
Isoxsuprine (Oral route,
injection route) side effects
- Mayo Clinic. (n.d.).
https://shorturl.at/cMPT7

StackPath. (n.d.)
.https://www.mims.com/p
hilippines/drug/info/isoxsu
prine?mtype=generic

DRUG NAME CLASSIFICATION / INDICATIONS CONTRAINDICATIONS ADVERSE EFFECTS NURSING

MECHANISM OF ACTION RESPONSIBILITY
BRAND NAME: CLASSIFICATION: Magnesium sulfate is Contraindicated in CNS (Central nervous Baseline Assessment
MgSO4 Therapeutic class: indicated for immediate patients with system):
hypersensitivity to  Assess the patient's
Electrolyte control of life-threatening  Confusion
magnesium salts or any hypersensitivity to
replacement convulsions in the  Decreased reflexes,
component of magnesium- magnesium.
GENERIC NAME: treatment of severe dizziness
magnesium sulfate Pharmacologic class: toxemias (pre-eclampsia containing preparations.
 Syncope  Assess GI pain
Mineral and eclampsia) of
Also, contradicted heart  Assess the patient's
DOSAGES AND pregnancy and in the CV (Cardiovascular):
block, MI, and respiratory rate and
FREQUENCIES: MECHANISM OF ACTION: treatment of acute preeclampsia 2 hours or  Arrhythmias
Hypomagnesemia Assists all enzymes nephritis in children.  Hypotension pattern to detect
less before delivery (I.V.
Mild: 1 g intramuscularly involved in phosphate respiratory
form).
(IM) every 6 hours for 4 transfer reactions that Also indicated for GI (Gastrointestinal): depression.
doses use adenosine replacement therapy in  Flatulence
Severe: 5 g intravenously triphosphate (ATP). magnesium deficiency,  Vomiting
(IV) over 3 hours Magnesium is required especially in acute Intervention/Evaluation
for the normal function hypomagnesemia MS (Musculoskeletal):
of the ATP-dependent  Muscle cramps  Be aware that the
Toxemia of Pregnancy accompanied by signs of
sodium-potassium pump drug isn’t
4-5 g (diluted in 250 tetany similar to those of
Respiratory: metabolized. Drug
mL NS/D5W) intravenously in muscle membranes. It hypocalcemia. Also used in
may effectively treat  Dyspnea remaining in the GI
(IV) in combination with uterine tetany as a
digitalis glycoside-  Respiratory tract produces
either (a) up to 10 g (10 myometrial relaxant.
induced arrhythmias depression or watery stool within
mL of undiluted 50%
because correction of paralysis 30 minutes to 3
solution) divided and
hypomagnesemia hours.
administered
Skin:
intramuscularly (IM) into improves the sodium-  Frequently assess
potassium pump’s ability  Diaphoresis
each buttock or (b) after cardiac status of
initial IV dose, 1-3 g/ hour to distribute potassium Other: patients taking drugs
IV. into intracellular spaces
 Hypermagnesemia that lower heart
and because magnesium
 Hypersensitivity rate, such as beta
decreases calcium uptake
Preterm Labor (Off-label) reactions blockers because
and potassium outflow
Loading dose: 4-6 g  Injection site pain or magnesium may
through myocardial cell
intravenously (IV) over 20 irritation (I.M. form) aggravate symptoms
membranes.
minutes; maintenance: 2-4  Laxative of heart block.
g/hour IV for 12-24 hours dependence
As a laxative, magnesium  Provide adequate
as tolerated after  Magnesium toxicity
exerts a hyperosmotic diet, exercise, and
contractions cease.
effect in the small fluids for patients
intestine. It causes water being treated for
retention that distends
the bowel and causes the constipation.
duodenum to secrete  Monitor serum
cholecystokinin. This electrolyte levels in
substance stimulates patients with renal
fluid secretion and insufficiency
intestinal motility. because they’re at
risk for magnesium
As an antacid, toxicity.
magnesium reacts with
water, converting  Be aware that
magnesium oxide to magnesium salts
magnesium hydroxide. aren’t intended for
Magnesium hydroxide long-term use. For
rapidly reacts with gastric example,
acid to form water and magnesium sulfate
magnesium chloride, may cause fetal
which increases gastric abnormalities if
pH. administered for
more than 5 to 7
As an anticonvulsant, days to pregnant
magnesium depresses women. When
the CNS and blocks magnesium sulfate is
peripheral administered by
neuromuscular impulse continuous I.V.
transmission by infusion (especially
decreasing available for more than 24
acetylcholine. hours preceding
delivery) to control
convulsions in a
toxemic woman,
monitor the
newborn for signs of
magnesium toxicity,
such as
neuromuscular or
respiratory
depression.
  Magnesium levels
must be monitored
after repeated
doses. Monitor
levels hourly in
patients with severe
hypomagnesemia

Patient/Family Teaching
 Advise patient to
chew magnesium
chewable tablets
thoroughly before
swallowing, and
then drink a full
glass of water.
Mention that tablets
have a chalky taste.
 Instruct patient to
take magnesium-
containing antacids
between meals and
at bedtime. Urge
him not to take
other drugs within 2
hours of the antacid.
 Tell the patient to
notify the prescriber
and avoid using
magnesium-
containing laxatives
if he has abdominal
pain, nausea, or
vomiting.
 Instruct patient to
refrigerate
magnesium citrate
solution.
 Caution patient
about the risk of
dependence with
long-term laxative
use.
 Teach the patient to
prevent constipation
by increasing dietary
fiber and fluid intake
and exercising
regularly.
 Explain the use and
administration of
the drug to the
patient and family.
 Tell the patient
about warning signs
of high and low
magnesium levels.
 Encourage the
patient to report
adverse effects.
 Instruct patient to
tell prescriber if
she’s pregnant or
planning to become
pregnant during
therapy.
 Document all aspects of
the patient’s treatment
(time, route, dosage,
patient’s response, any
side/adverse effects.
REFERENCE:
Comerford, K. C.,
& Durkin, M. T.
(2021). Nursing 2021
drug handbook. 41st
edition. Philadelphia,
Wolters Kluwer.

Kizior, R.J. & Hodgson,

K.J., (2023). Saunders
Nursing Drug Handbook.
Elsevier, St. Louis,
Missouri.

Jones & Bartlett Learning

(2023). 2022 Nurse’s Drug
Handbook, 21st Edition.

Magnesium sulfate: Uses,

Interactions, Mechanism of
Action | DrugBank Online.
(n.d.). DrugBank.
https://go.drugbank.com/d
rugs/DB00653

Magnesium sulfate:
generic, uses, side effects,
dosages, interactions &
warnings. (2021, August
13). RxList.
https://www.rxlist.com/m
agnesium_sulfate/generic-
 drug.htm

Comerford, K. C., & Durkin,

M. T. (2021). Nursing 2021
drug handbook. 41st
edition. Philadelphia,
Wolters Kluwer.

DRUG NAME CLASSIFICATION / INDICATIONS CONTRAINDICATIONS ADVERSE EFFECTS NURSING

MECHANISM OF ACTION RESPONSIBILITY
BRAND NAME: CLASSIFICATION: 1. Indicated to induce or Contraindicated in SIDE EFFECTS Medication:
Pitocin Therapeutic class: stimulate labor. patients with Occasional: IV Route
Oxytocic agent hypersensitivity to  Tachycardia
oxytocin.  Never give drugs
GENERIC NAME: 2. Indicated to reduce  Premature
simultaneously by
oxytocin Pharmacologic class: postpartum bleeding ventricular
Adequate uterine activity more than one
Uterine smooth muscle after expulsion of the contractions
that fails to progress, route. Never give
DOSAGES AND stimulant placenta.  Hypotension
cephalopelvic drugs
FREQUENCY: disproportion, fetal  Nausea
simultaneously by
Based on each indication MECHANISM OF ACTION: 3. And incomplete, distress without imminent  Vomiting
more than one
by number: Activates receptors that inevitable, or elective delivery, grand multiparity,
trigger an increase in route.
1. Adults: Initially, 0.5 to abortion hyperactive or hypertonic Rare
1 milliunit/minute IV intracellular calcium uterus, obstetric Nasal:  Don't give bolus
infusion. Increase the levels in uterine emergencies that favor  Lacrimation/tearing injection; use an
rate by 1 to 2 myofibrils; and increases surgical intervention,  Nasal irritation infusion pump.
milliunits/minute at prostaglandin prematurity, unengaged  Rhinorrhea
30- to 60-minute production. fetal head, unfavorable  Give the drug only
 Unexpected uterine
intervals until a normal fetal by piggyback
bleeding/
contraction pattern is Therapeutic Effect: position/presentation, infusion so that it
contractions
established. Decrease Stimulates uterine when vaginal delivery is may be stopped
rate when labor is contractions contraindicated (e.g., without
active genital herpes ADVERSE EFFECTS
firmly established. interrupting the IV
infection, invasive cervical Maternal line.
Rates exceeding 9 to CNS (Central nervous
cancer, placenta previa,
10 milliunits/minute cord presentation). system):  Alert: All patients
are rarely required.  Subarachnoid receiving oxytocin
2. Adults: 10 to 40 units hemorrhage IV must be under
in 1,000 mL of lactated  Seizures continuous
Ringer solution, or NSS  Coma observation by
 IV infused at the rate
CV (Cardiovascular): trained personnel
needed to sustain
 HTN who have a
uterine contraction
 PVCs thorough
and control uterine
 Hypotension knowledge of the
atony. Also, may give
 Tachycardia drug.
10 units IM after
delivery of the  Alert: Discontinue
placenta. GI (Gastrointestinal):
oxytocin infusion
3. Adults: 10 units IV  Nausea
immediately if
 Vomiting
infusion at 10 to 20 uterine
milliunits (20 to 40 hyperactivity or
GU (Genitourinary):
drops)/minute. Don't fetal distress
 abruptio placentae
exceed 30 units in 12 occurs. Administer
 Tetanic uterine
hours. oxygen to the
contractions
 Postpartum mother. The
hemorrhage mother and fetus
 Uterine rupture must be evaluated
 Impaired uterine by the responsible
blood flow practitioner.
 Pelvic hematoma
 Increased uterine IM Route
motility  Never give drugs
simultaneously by
Hematologic:
more than one
 Afibrinogenemia
route.
 Possibly related to
postpartum
Baseline Assessment
bleeding
 Pelvic hematoma  Assess baselines for
vital signs, blood
Other: pressure, and fetal
 Anaphylaxis heart rate.
 Death from
oxytocin-induced  Determine the
water intoxication frequency,
 Hypersensitivity duration, and
reactions strength of
 contractions.
Fetal
CNS (Central nervous
system):
 Infant brain damage Intervention/Evaluation
 Seizures  Monitor blood
pressure, pulse,
CV (Cardiovascular)
respirations, fetal
 Bradycardia,
heart rate,
arrhythmias
intrauterine
 PVCS
pressure, and
contractions
EENT (Eye, Ear, Nose, and
Throat): (duration, strength,
 Neonatal retinal frequency) q 15
hemorrhage min.
 Notify the physician
Hepatic: of contractions that
 Neonatal jaundice last longer than 1
min, occur more
Other:
frequently than
 Low Apgar scores at
every 2 min, or
5 minutes, death
stop.
 Maintain careful
I&O; be alert to
potential water
intoxication.
 Check for blood
loss.
 Drug is used to
induce or reinforce
labor only when the
pelvis is known to
be adequate when
vaginal delivery is
indicated, when
 fetal maturity is
assured, and when
the fetal position is
favorable. Use
drugs only in
hospitals where
critical care
facilities and
prescribers are
immediately
available.
 Monitor fluid intake
and output. The
antidiuretic effect
may lead to fluid
overload, seizures,
and coma from
water intoxication.
 Monitor and record
uterine
contractions, HR,
BP, intrauterine
pressure, fetal HR,
and blood loss at
least every 15
minutes.

Patient/Family Teaching
 Keep patient, and
family informed of
labor progress.
 Explain the use and
administration of
the drug to the
 patient and family.
 Instruct patient to
promptly report
adverse reactions.

Document all aspects of

the patient’s treatment
(time, route, dosage,
patient’s response, any
side/adverse effects.
REFERENCE:
Comerford, K. C.,
& Durkin, M. T.
(2021). Nursing 2021
drug handbook. 41st
edition. Philadelphia,
Wolters Kluwer.

Kizior, R.J. & Hodgson,

K.J., (2023). Saunders
Nursing Drug Handbook.
Elsevier, St. Louis,
Missouri.

Jones & Bartlett Learning

(2023). 2022 Nurse’s Drug
Handbook, 21st Edition.

DRUG NAME CLASSIFICATION / INDICATIONS CONTRAINDICATIONS ADVERSE EFFECTS NURSING

MECHANISM OF ACTION RESPONSIBILITY
BRAND NAME: CLASSIFICATION: Oral: Contraindicated in Common: Administration
Progesterone Progestins (pregnen (4) Disorders associated with patients with  Altered menstrual
hypersensitivity to the  Verify the healthcare
derivative progestogens a progesterone deficit: cycles
active substance or any of provider's
GENERIC NAME: pre-menstrual syndrome,  Amenorrhea
the excipients. prescription for the
utrogestan menstrual irregularity, (absence of
Severe changes in hepatic correct dose and
MECHANISM OF ACTION: benign breast disease, pre- menstruation)
function.
DOSAGES AND Contains progesterone in menopause.  Intermenstrual
micronized form, and It should not be prescribed administration
FREQUENCIES: bleeding
significantly increases to nursing mothers. route.
Oral: 100 mg or 200 mg. Treatment of the  Headaches
Vaginal: 200 mg. plasma progesterone menopause (as an  Confirm the
levels following oral and adjuvant to estrogen Uncommon: patient's medical
vaginal administration, therapy).  Drowsiness history and reason
thus making it possible to  Transient dizziness for the Utrogestan
correct any deficits in Infertility caused by luteal  Cholestatic jaundice treatment.
progesterone. phase defect.  Pruritus (itching)
 Ensure the patient is
 Gastrointestinal
Menace of abortion or not allergic to
disorders
prevention of recurrent progesterone or any
spontaneous abortions components of
Drowsiness and transient
due to diagnosed luteal Utrogestan.
dizziness are more likely in
phase defect. patients with low estrogen  Educate the patient
levels and can be reversed about the purpose,
Menace of preterm by adjusting the dosage, potential
delivery. medication dosage or side effects, and
increasing estrogen doses. proper
Vaginal: administration
Starting treatment too technique.
During In Vitro early may shorten the
Fertilization cycles (IVF). menstrual cycle or cause  Prepare the
intermenstrual bleeding. medication
Menace of abortion or according to the
prevention of recurrent Local irritation can occur prescription,
spontaneous abortions after vaginal whether oral or
due to luteal phase defect. administration due to the vaginal
presence of soya lecithin administration.
Menace of preterm and peanut oil in the soft  Provide clear
delivery. capsules. instructions to the
patient for self-
The use of Progesterone
administration, if
(Utrogestan) soft capsules
applicable.
is not contraindicated
during pregnancy  For vaginal
including the first few administration,
weeks.
explain the correct
positioning and
insertion technique.
 Ensure that the
patient understands
the timing and
frequency of
administration.

Baseline Assessment
 Monitor the
patient's menstrual
cycle and inform
them of the
appropriate start
date if necessary.
 Monitor for any
signs of allergic
reactions or adverse
effects, such as
itching, rash, or
swelling.
 Evaluate the
patient's response to
treatment, including
any changes in
menstrual patterns.

Intervention/Evaluation
 Ensure that patients
are aware of the risk
of drowsiness or
transient dizziness
 and advise them not
to engage in
activities requiring
full alertness until
these effects
subside.
 Monitor patients
with low estrogen
levels for drowsiness
and dizziness and
coordinate with the
healthcare provider
for necessary
adjustments.
 Keep a record of any
intermenstrual
bleeding or changes
in menstrual cycles.
 Monitor for
potential signs of
cholestatic jaundice,
such as yellowing of
the skin or eyes, and
report to the
healthcare provider.
 In the case of missed
doses, guide what to
do, including
whether to take a
missed dose as soon
as remembered.

Patient/Family Teaching
 Educate the patient
on the importance
of taking the
medication as
prescribed and not
doubling the dose if
a dose is missed.
 Address any
questions or
concerns the patient
may have about
their treatment.
 Emphasize the
significance of
reporting any
unusual or severe
side effects to the
healthcare provider.
 Encourage patients
to maintain proper
hydration and
overall well-being
during treatment.
 Provide emotional
support and
reassurance to
patients
experiencing anxiety
or discomfort due to
their condition or
treatment.
 Be prepared to
address any
potential
 emergencies or
adverse reactions
promptly.
 Stay updated on the
latest guidelines and
best practices
related to
Utrogestan
administration and
progesterone
therapy.

Document all aspects of

the patient’s treatment
(time, route, dosage,
patient’s response, any
side/adverse effects.
REFERENCE:
StackPath. (n.d.-d).
https://www.mims.com/p
hilippines/drug/info/utrog
estan?type=full

Name of Student:
CUTAMORA, Tonni Fritz H.