Code No: BP602T PCI SET - 1
III B. Pharmacy II Semester Regular Examinations, Oct/Nov - 2020
PHARMACOLOGY - III
Time: 3 hours Max. Marks: 75
Note: 1. Question paper consists of three parts (Part-I, Part-II & Part-III)
2. Answer ALL (Multiple Choice) Questions from Part-I
3. Answer any TWO Questions from Part-II
4. Answer any SEVEN Questions from Part-III
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PART –I
1. (i) Identify the long acting Beta2-adrenoreceptor (1M)
(a) Salbutamol (b) Terbutaline (c) Salmeterol (d) Theophylline
(ii) Identify the weak opioid (1M)
(a) Morphine (b) Codeine (c) Dextromethorphan (d) Beractant
(iii) Proton pump inhibitors should be used in caution in patients with (1M)
(a) Liver disease (b) Cardiac disorder (c) Breast cancer (d) lung diseases
(iv) Uterine contractions can occur for (1M)
(a) Sucralfate (b) Omeprazole (c) Magnesium hydroxide (d) Misoprostol
(v) Inhibition of transpeptidation can be seen in (1M)
(a) Aminoglycosides (b) Chloramphenicol (c) Erythromycin (d) Gentamycin
(vi) Which of the following is not a Beta-lactum antibiotic (1M)
(a) Penicillins (b) Cephalosporins (c) Monobactams (d) Tetracyclines
(vii) Nephrotoxicity is the major adverse effect of (1M)
(a) Gentamycin (b) Erythromycin (c) Ciprofloxacin (d) Nalidixic acid
(viii) Quinolone agents inhibit (1M)
(a) Topoisomerase I (b) Topoisomerase II
(c) Topoisomerase IV (d) Topoisomerase VI
(ix) Identify the drug whose use is mainly limited to Candida infections of skin (1M)
(a) Amphotericin (b) Nystatin (c) Griseofulvin (d) Flucytosine
(x) The first drug introduced for the treatment of HIV is (1M)
(a) Nevirapine (b) Ritonavir (c) Zidovudine (d) Etraverine
(xi) The duration of intial phase of treatment for tuberculosis is about (1M)
(a) 3 months (b) 2 months (c) 4 month (d) 6 months
(xii) Which anthelminthic drug is considered safe for preganant and lactating (1M)
women
(a) Mebendazole (b) Piperazine (c) Praziquantel (d) Diethylcarbamazine
(xiii) Identify the drug which comes under Nitrogen mustards (1M)
(a) Chlorambucil (b) Carmustine (c) Busulfan (d) Cisplatin
(xiv) The drug for germline cancer is (1M)
(a) Vincristine (b) Bleomycin (c) Etoposide (d) Campothecans
(xv) Identify the drug which can be used prevent organ rejection (1M)
(a) Sulphasalazine (b) Chloroquine (c) Penicillamine (d) Sirolimus
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Code No: BP602T PCI SET - 1
(xvi) A biosimilar is (1M)
(a) A biological medical product highly similar to another already approved
(b) A vaccine product highly similar to another already approved
(c) A biological medical product highly not similar to another already
approved
(d) A medical device product
(xvii) Identify the antidote for paracetamol poisoning (1M)
(a) Atropine (b) Acetylcysteine (c) Dantrolene (d) Ethanol
(xviii) Hyperkeratosis is a clinical feature of which poisoning (1M)
(a) Aresenic (b) lead (c) Barbiturates (d) Morphine
(xix) What is the antidote of organophosphorous poisoning (1M)
(a) Neostigmine (b) Penicillamine (c) Atropine (d) Copper
(xx) Pthalidomide is an example of (1M)
(a) Mutagenicity (b) Teratogenicity (c) Carcinogenicity (d) Genotoxicity
PART -II
2. a) Discuss the role of glucocorticoids in the treatment of Asthma? (5M)
b) Discuss the mechanism of action, clinical uses and adverse effects of (5M)
sulphonamides?
3. a) Discuss the pharmacology of Isoniazid and Rifampicin? (5M)
b) Discuss the mechanism of action, pharmacokinetic aspects and unwanted effects (5M)
of Quinine?
4. a) Discuss the pharmacology of drugs used in Syphilis? (5M)
b) Explain the clinical uses of immunosuppressant’s? (5M)
PART -III
5. Discuss the mechanism of action and clinical uses of Monteleukast? (5M)
6. Discuss the Pharmacology of Anti tussives? (5M)
7. Discuss the pharmacology of any 2 drugs that protect the mucosa of stomach? (5M)
8. Write briefly about resistance to antibacterial drugs? (5M)
9. Write the mechanism of action and clinical uses of tetracyclines? (5M)
10. Write the pharmacology of synthetic antifungal agents? (5M)
11. Write about the general principles of cytotoxic anticancer drugs? (5M)
12. Discuss about teratogenicity with examples? (5M)
13. Discuss the management of morphine poisoning? (5M)
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