Biology Paper 1 2024 Predictions

Key:

*The number next to the specification point corresponds to the number of times a
question based on that specification point was asked that year

*The practicals section is a list of practicals that were referenced in the paper that year

*The colour on the predicted specification points corresponds to how likely it is to come
up, and how focused it will be around that. Green = very likely, red = very unlikely.

2018:
Practicals:

- RP2 Investigate the effect of antiseptics or antibiotics on bacterial growth using agar plates
and measuring zones of inhibition.
- RP3 Investigate the effect of a range of concentrations of salt or sugar solutions on the mass
of plant tissue.
- RP4 Use qualitative reagents to test for a range of carbohydrates, lipids, and proteins.

Topic 1:

- 4.1.3.2 Osmosis (3)

- 4.1.3.3 Active Transport (1)
- 4.1.1.2 Animal and plant cells (1)
- 4.1.2.1 Chromosomes (1)
- 4.1.2.3 Stem cells (2)
- 4.1.1.6 Culturing microorganisms (1)

Topic 2:

- 4.2.2.3 Blood (1)

- 4.2.2.6 The effect of lifestyle on some non-communicable diseases (1)
- 4.2.2.2 The heart and blood vessels (6)
- 4.2.3.2 Plant organ system (1)
- 4.2.2.1 The human digestive system (4)

Topic 3:

- 4.3.1.1 Communicable (infectious) diseases (3)

- 4.3.1.8 Antibiotics and painkillers (1)
- 4.3.1.2 Viral diseases (1)
- 4.3.1.6 Human defence systems (1)
- 4.3.1.9 Discovery and development of drugs (1)
- 4.3.3.1 Detection and identification of plant diseases (1)
 - 4.3.2.1 Producing monoclonal antibodies (1)

Topic 4:

- 4.4.2.3 Metabolism (1)

- 4.4.2.1 Aerobic and anaerobic respiration (1)

2019:
Practicals:

- RP1 Use a light microscope to observe, draw and label a selection of plant and animal cells.
- RP6 Investigate the effect of light intensity on the rate of photosynthesis using an aquatic
organism such as pondweed.

Topic 1:

- 4.1.1.2 Animal and plant cells (2)

- 4.1.1.1 Eukaryotes and prokaryotes (1)
- 4.1.1.5 Microscopy (2)
- 4.1.3.2 Osmosis (1)
- 4.1.3.1 Diffusion (2)
- 4.1.2.3 Stem cells (2)

Topic 2:

- 4.2.3.1 Plant tissues (1)

- 4.2.3.2 Plant organ system (4)
- 4.2.2.4 Coronary heart disease: a non-communicable disease (3)
- 4.2.2.2 The heart and blood vessels (4)
- 4.2.2.3 Blood (2)
- 4.2.2.1 The human digestive system (6)
-

Topic 3:

- 4.3.1.5 Protist diseases (1)

- 4.3.1.6 Human defence systems (1)
- 4.3.1.9 Discovery and development of drugs (2)
- 4.3.2.2 Uses of monoclonal antibodies (1)

Topic 4:

- 4.4.1.1 Photosynthetic reaction (1)

- 4.4.1.2 Rate of photosynthesis (2)
- 4.4.2.1 Aerobic and anaerobic respiration (2)
- 4.4.2.2 Response to exercise (1)
2020:
Practicals:

- RP6 Investigate the effect of light intensity on the rate of photosynthesis using an aquatic
organism such as pondweed.

Topic 1:

- 4.1.3.1 Diffusion (2)

- 4.1.3.2 Osmosis (1)
- 4.1.3.3 Active Transport (1)
- 4.1.1.1 Eukaryotes and prokaryotes (2)
- 4.1.2.2 Mitosis and the cell cycle (3)

Topic 2:

- 4.2.2.1 The human digestive system (8)

- 4.2.3.1 Plant tissues (1)
- 4.2.2.2 The heart and blood vessels (1)
- 4.2.2.6 The effect of lifestyle on some non-communicable diseases (3)

Topic 3:

- 4.3.3.2 Plant defence responses (3)

- 4.3.3.1 Detection and identification of plant diseases (1)
- 4.3.1.4 Fungal diseases (1)
- 4.3.1.9 Discovery and development of drugs (2)
- 4.3.2.2 Uses of monoclonal antibodies (1)
- 4.3.1.6 Human defence systems (1)

Topic 4:

- 4.4.1.2 Rate of photosynthesis (1)

- 4.4.1.1 Photosynthetic reaction (4)
- 4.4.1.3 Uses of glucose from photosynthesis (3)
- 4.4.2.1 Aerobic and anaerobic respiration (1)

2021:
Practicals:

- RP1 Use a light microscope to observe, draw and label a selection of plant and animal cells.
 - RP2 Investigate the effect of antiseptics or antibiotics on bacterial growth using agar plates
and measuring zones of inhibition.
- RP5 Investigate the effect of pH on the rate of reaction of amylase enzyme.

Topic 1:

- 4.1.1.5 Microscopy (4)

- 4.1.1.2 Animal and plant cells (4)

- 4.1.3.2 Osmosis (1)
- 4.1.1.6 Culturing microorganisms (4)

Topic 2:

- 4.2.2.3 Blood (1)

- 4.2.2.6 The effect of lifestyle on some non-communicable diseases (2)

- 4.2.2.1 The human digestive system (5)
- 4.2.3.1 Plant tissues (1)
- 4.2.3.2 Plant organ system (5)
- 4.2.2.7 Cancer (2)
- 4.2.2.3 Blood (1)
-

Topic 3:

- 4.3.1.6 Human defence systems (3)

Topic 4:

- 4.4.2.1 Aerobic and anaerobic respiration (7)

- 4.4.1.1 Photosynthetic reaction (3)

2022:
Practicals:

- RP3 Investigate the effect of a range of concentrations of salt or sugar solutions on the mass
of plant tissue.
- RP1 Use a light microscope to observe, draw and label a selection of plant and animal cells.

Topic 1:

- 4.1.1.2 Animal and plant cells (3)

- 4.1.3.2 Osmosis (5)
- 4.1.1.1 Eukaryotes and prokaryotes (1)
- 4.1.1.6 Culturing microorganisms (1)
- 4.1.1.5 Microscopy (7)
 - 4.1.2.2 Mitosis and the cell cycle (1)
- 4.1.1.4 Cell differentiation (1)
- 4.1.3.1 Diffusion (5)

Topic 2:

- 4.2.3.2 Plant organ system (7)

- 4.2.2.1 The human digestive system (3)

Topic 3:

- 4.3.1.4 Fungal diseases (1)

- 4.3.3.2 Plant defence responses (2)
- 4.3.3.1 Detection and identification of plant diseases (1)
- 4.3.1.2 Viral diseases (1)
- 4.3.1.7 Vaccination (1)
- 4.3.2.1 Producing monoclonal antibodies (2)

Topic 4:

- 4.4.2.3 Metabolism (1)

2023:
Practicals:

- RP2 Investigate the effect of antiseptics or antibiotics on bacterial growth using agar plates
and measuring zones of inhibition.
- RP6 Investigate the effect of light intensity on the rate of photosynthesis using an aquatic
organism such as pondweed.

Topic 1:

- 4.1.2.3 Stem cells (1)

- 4.1.1.6 Culturing microorganisms (5)
- 4.1.3.2 Osmosis (1)
- 4.1.1.2 Animal and plant cells (1)
- 4.1.1.1 Eukaryotes and prokaryotes (1)
- 4.1.2.2 Mitosis and the cell cycle (1)

Topic 2:

- 4.2.1 Principles of organisation (1)

- 4.2.2.2 The heart and blood vessels (7)
- 4.2.2.4 Coronary heart disease: a non-communicable disease (2)
- 4.2.2.1 The human digestive system (1)
- 4.2.2.3 Blood (1)
- 4.2.2.5 Health issues (1)
 Topic 3:

- 4.3.1.9 Discovery and development of drugs (2)

- 4.3.3.1 Detection and identification of plant diseases (1)
- 4.3.1.1 Communicable (infectious) diseases (1)
- 4.3.1.7 Vaccination (1)
- 4.3.1.6 Human defence systems (1)
- 4.3.1.8 Antibiotics and painkillers (1)
- 4.3.2.1 Producing monoclonal antibodies (3)
- 4.3.1.5 Protist diseases (1)

Topic 4:

- 4.4.2.1 Aerobic and anaerobic respiration (4)

- 4.4.2.2 Response to exercise (1)
- 4.4.1.2 Rate of photosynthesis (3)
- 4.4.1.1 Photosynthetic reaction (1)

Specimen:
Practicals:

- RP3 Investigate the effect of a range of concentrations of salt or sugar solutions on the mass
of plant tissue.

Topic 1:

- 4.1.3.3 Active Transport (1)

- 4.1.3.1 Diffusion (2)
- 4.1.3.2 Osmosis (4)
- 4.1.2.2 Mitosis and the cell cycle (3)
- 4.1.1.6 Culturing microorganisms (2)
-

Topic 2:

- 4.2.3.2 Plant organ system (4)

- 4.2.2.1 The human digestive system (4)
- 4.2.2.3 Blood (1)
- 4.2.2.7 Cancer (1)

- 4.2.2.2 The heart and blood vessels (1)

-

Topic 3:

- 4.3.1.2 Viral diseases (2)

 - 4.3.1.6 Human defence systems (1)
- 4.3.1.9 Discovery and development of drugs (1)
- 4.3.3.1 Detection and identification of plant diseases (4)
- 4.3.1.5 Protist diseases (2)
- 4.3.1.1 Communicable (infectious) diseases (1)
- 4.3.2.2 Uses of monoclonal antibodies (2)
- 4.3.2.1 Producing monoclonal antibodies (1)

Topic 4:

- 4.4.1.1 Photosynthetic reaction (1)

- 4.4.1.3 Uses of glucose from photosynthesis (1)
- 4.4.2.1 Aerobic and anaerobic respiration (4)

Practicals Summary:
- RP1 Use a light microscope to observe, draw and label a selection of plant and animal cells.
(3)
- RP2 Investigate the effect of antiseptics or antibiotics on bacterial growth using agar plates
and measuring zones of inhibition. (3)
- RP3 Investigate the effect of a range of concentrations of salt or sugar solutions on the mass
of plant tissue. (3)
- RP4 Use qualitative reagents to test for a range of carbohydrates, lipids, and proteins. (1, but
comes up frequently throughout paper as low marks)
- RP5 Investigate the effect of pH on the rate of reaction of amylase enzyme. (1)
- RP6 Investigate the effect of light intensity on the rate of photosynthesis using an aquatic
organism such as pondweed. (3)

Content Summary:
Topic 1:

- 4.1.1.1 Eukaryotes and prokaryotes (5)

- 4.1.1.2 Animal and plant cells (11)
- 4.1.1.3 Cell specialisation (0)
- 4.1.1.4 Cell differentiation (1)
- 4.1.1.5 Microscopy (13)
- 4.1.1.6 Culturing microorganisms (13)
- 4.1.2.1 Chromosomes (1)
- 4.1.2.2 Mitosis and the cell cycle (8)
- 4.1.2.3 Stem cells (5)
- 4.1.3.1 Diffusion (11)
- 4.1.3.2 Osmosis (16)
- 4.1.3.3 Active transport (3)
 Topic 2:

- 4.2.1 Principles of organisation (1)

- 4.2.2.1 The human digestive system (31)
- 4.2.2.2 The heart and blood vessels (19)
- 4.2.2.3 Blood (7)
- 4.2.2.4 Coronary heart disease: a non-communicable disease (5)
- 4.2.2.5 Health issues (1)
- 4.2.2.6 The effect of lifestyle on some non-communicable diseases (6)
- 4.2.2.7 Cancer (3)
- 4.2.3.1 Plant tissues (3)
- 4.2.3.2 Plant organ system (21)

Topic 3:

- 4.3.1.1 Communicable (infectious) diseases (5)

- 4.3.1.2 Viral diseases (4)
- 4.3.1.3 Bacterial diseases (0)
- 4.3.1.4 Fungal diseases (2)
- 4.3.1.5 Protist diseases (4)
- 4.3.1.6 Human defence systems (8)
- 4.3.1.7 Vaccination (2)
- 4.3.1.8 Antibiotics and painkillers (2)
- 4.3.1.9 Discovery and development of drugs (8)
- 4.3.2.1 Producing monoclonal antibodies (7)
- 4.3.2.2 Uses of monoclonal antibodies (4)
- 4.3.3.1 Detection and identification of plant diseases (8)
- 4.3.3.2 Plant defence responses (5)

Topic 4:

- 4.4.1.1 Photosynthetic reaction (10)

- 4.4.1.2 Rate of photosynthesis (6)
- 4.4.1.3 Uses of glucose from photosynthesis (4)
- 4.4.2.1 Aerobic and anaerobic respiration (19)
- 4.4.2.2 Response to exercise (2)
- 4.4.2.3 Metabolism (2)

2024 Predicted Paper:

Practicals:

- RP5 Investigate the effect of pH on the rate of reaction of amylase enzyme.

- RP4 Use qualitative reagents to test for a range of carbohydrates, lipids, and proteins.

Topic 1:

- 4.1.1.1 Eukaryotes and prokaryotes

- 4.1.1.2 Animal and plant cells
 - 4.1.1.3 Cell specialisation
- 4.1.1.4 Cell differentiation
- 4.1.1.5 Microscopy
- 4.1.1.6 Culturing microorganisms
- 4.1.2.1 Chromosomes
- 4.1.2.2 Mitosis and the cell cycle
- 4.1.2.3 Stem cells
- 4.1.3.1 Diffusion
- 4.1.3.2 Osmosis
- 4.1.3.3 Active transport

Topic 2:

- 4.2.1 Principles of organisation

- 4.2.2.1 The human digestive system
- 4.2.2.2 The heart and blood vessels
- 4.2.2.3 Blood
- 4.2.2.4 Coronary heart disease: a non-communicable disease
- 4.2.2.5 Health issues
- 4.2.2.6 The effect of lifestyle on some non-communicable diseases
- 4.2.2.7 Cancer
- 4.2.3.1 Plant tissues
- 4.2.3.2 Plant organ system

Topic 3:

- 4.3.1.1 Communicable (infectious) diseases

- 4.3.1.2 Viral diseases
- 4.3.1.3 Bacterial diseases
- 4.3.1.4 Fungal diseases
- 4.3.1.5 Protist diseases
- 4.3.1.6 Human defence systems
- 4.3.1.7 Vaccination
- 4.3.1.8 Antibiotics and painkillers
- 4.3.1.9 Discovery and development of drugs
- 4.3.2.1 Producing monoclonal antibodies
- 4.3.2.2 Uses of monoclonal antibodies
- 4.3.3.1 Detection and identification of plant diseases
- 4.3.3.2 Plant defence responses

Topic 4:

- 4.4.1.1 Photosynthetic reaction

- 4.4.1.2 Rate of photosynthesis
- 4.4.1.3 Uses of glucose from photosynthesis
- 4.4.2.1 Aerobic and anaerobic respiration
- 4.4.2.2 Response to exercise
- 4.4.2.3 Metabolism